World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
31099
World Ranking
1838
National Ranking
124

Research.com Recognitions

  • 1999 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Physiology and Pharmacology/Toxicology
  • 1992 - Member of Academia Europaea
  • 1982 - Robert Koch Prize

Overview

Franz Oesch is affiliated with Johannes Gutenberg University of Mainz in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a concentration on pharmacology, cancer research, and molecular biology. Additional areas of study include health, toxicology and mutagenesis, and organic chemistry.

The scientist's work addresses multiple topics, notably carcinogens and genotoxicity assessment, pharmacological effects of natural compounds, pesticide exposure and toxicity, cytokine signaling pathways and interactions, NF-κB signaling pathways, pharmacological effects of medicinal plants, and bone metabolism and diseases.

Oesch has contributed to various publication venues, frequently appearing in:

  • Archives of Toxicology
  • Medicinal Research Reviews
  • Seminars in Cancer Biology
  • Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
  • Phytomedicine

Recent papers authored or co-authored by Oesch include:

  • "Toxicity as prime selection criterion among SARS-active herbal medications," published in 2021 in Phytomedicine
  • "N-vinyl compounds: studies on metabolism, genotoxicity, carcinogenicity," published in 2021 in Archives of Toxicology
  • "Genotoxicity testing of nanomaterials," published in 2022 in Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology (co-authored with Robert Landsiedel)
  • "The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseases," 2021, Medicinal Research Reviews (co-authored with Thomas Efferth)
  • "Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities," 2020, Seminars in Cancer Biology (co-authored with Thomas Efferth)

Frequent co-authors of Oesch include Robert Landsiedel, Eric Fabian, Thomas Efferth, Naveed Honarvar, and Franz Berger.

Oesch has been recognized with several awards, including membership in the German National Academy of Sciences Leopoldina in 1999 for work in physiology and pharmacology/toxicology, membership in Academia Europaea since 1992, and the Robert Koch Prize awarded in 1982.

Best Publications

  • Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.

    Franz Oesch

  • A radiometric assay for hepatic epoxide hydrase activity with [7-3H] styrene oxide☆

    F. Oesch;D.M. Jerina;J. Daly

  • A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms.

    Michael Arand;Roland Mühlbauer;Jan Hengstler;Elke Jäger

  • Genotoxicity investigations on nanomaterials: Methods, preparation and characterization of test material, potential artifacts and limitations—Many questions, some answers

    Robert Landsiedel;Maike Diana Kapp;Markus Schulz;Karin Wiench

  • Immunoselection in vivo : independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma

    Elke Jäger;Mark Ringhoffer;Michael Altmannsberger;Michael Arand

  • Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic-T-cell responses: evidence for immunoselection of antigen-loss variants in vivo.

    Elke Jäger;Mark Ringhoffer;Julia Karbach;Michael Arand

  • Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron.

    Thomas Efferth;Achille Benakis;Marta R. Romero;Maja Tomicic

  • Adverse outcome pathways: opportunities, limitations and open questions.

    Marcel Leist;Ahmed Ghallab;Ahmed Ghallab;Rabea Graepel;Rosemarie Marchan

  • Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo

    Elke Jäger;Mark Ringhoffer;Hans Peter Dienes;Michael Arand

  • Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction.

    Jan G. Hengstler;D. Utesch;P. Steinberg;K. L. Platt

  • Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected

    Jan G. Hengstler;Ulrich Bolm-Audorff;Andreas Faldum;Kai Janssen

  • New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures.

    Rolf Gebhardt;Jan G Hengstler;Dieter Müller;Reinhild Glöckner

  • Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.

    J. G. Hengstler;M. Arand;M. E. Herrero;F. Oesch

  • Of mice and models: improved animal models for biomedical research.

    Ernesto Bockamp;Marko Maringer;Christian Spangenberg;Stephan Fees

  • Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases.

    J Zou;B M Hallberg;T Bergfors;F Oesch

  • Drug-metabolizing enzymes in the skin of man, rat, and pig.

    Franz Oesch;Eric Fabian;Barbara Oesch-Bartlomowicz;Christoph Werner

  • Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins Implication for the potential catalytic mechanism of enzymatic epoxide hydrolysis

    Michael Arand;David F. Grant;Jeffrey K. Beetham;Thomas Friedberg

  • Conversion of naphthalene to trans-naphthalene dihydrodiol: Evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomes

    F. Oesch;J. Daly

  • Aryl hydrocarbon receptor activation by cAMP vs. dioxin : Divergent signaling pathways

    Barbara Oesch-Bartlomowicz;Andrea Huelster;Oliver Wiss;Patricia Antoniou-Lipfert

  • Purification and specificity of a human microsomal epoxide hydratase.

    Franz Oesch

Frequent Co-Authors

Hansruedi Glatt
Hansruedi Glatt Federal Institute for Risk Assessment
Michael Arand
Michael Arand University of Zurich
Jan G. Hengstler
Jan G. Hengstler TU Dortmund University
Albrecht Seidel
Albrecht Seidel Johannes Gutenberg University of Mainz
Robert Landsiedel
Robert Landsiedel BASF (United States)
Larry W. Robertson
Larry W. Robertson University of Iowa
David H. Phillips
David H. Phillips King's College London
John W. Daly
John W. Daly National Institutes of Health
Sherry L. Mowbray
Sherry L. Mowbray Uppsala University
Maria de Lourdes Bastos
Maria de Lourdes Bastos University of Porto

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in Biology and Biochemistry, there are several flexible online degree options that open doors to dynamic careers in health, science, and wellness. An online bachelor's degree in exercise science is ideal for those passionate about human physiology, sports performance, and rehabilitation. This pathway prepares graduates for roles in fitness training, health promotion, and clinical exercise environments.

Another related field is kinesiology, where pursuing an online kinesiology degree provides a solid foundation for careers in physical therapy, coaching, and wellness consulting. These programs are designed for students who wish to blend biological sciences with the study of movement and physical health.

For advanced degree holders seeking to transition quickly into nursing specialties, consider the shortest post master's pmhnp online programs. These certificates focus on psychiatric mental health and can fast-track your pathway to become a mental health nurse practitioner. Similarly, the fastest post master's fnp certificate allows nurses to rapidly qualify as family nurse practitioners. These accelerated options cater to professionals aiming to expand their expertise and career opportunities in the healthcare sector.

Best Scientists Citing Franz Oesch

Trending Scientists

Recently Published Articles