His main research concerns Biochemistry, Microsome, Glutathione, Internal medicine and Endocrinology. As part of one scientific family, Joseph W. DePierre deals mainly with the area of Biochemistry, narrowing it down to issues related to the Molecular biology, and often Programmed cell death and Apoptosis. His work in Glutathione reductase and Glutathione S-transferase are all subfields of Glutathione research.
His work in Glutathione reductase addresses issues such as GPX3, which are connected to fields such as GPX1. In general Internal medicine, his work in Spleen, Cytokine and Inflammation is often linked to Imipramine linking many areas of study. His Endocrinology research is multidisciplinary, incorporating perspectives in Viability assay, Bcl-xL, Mitochondrion and Pharmacology.
His primary areas of investigation include Biochemistry, Internal medicine, Endocrinology, Microsome and Enzyme. His Biochemistry study frequently links to adjacent areas such as Molecular biology. He works mostly in the field of Internal medicine, limiting it down to concerns involving Immune system and, occasionally, Antibody and Inflammation.
Joseph W. DePierre has researched Endocrinology in several fields, including Protein subunit and Gentamicin. His Microsome study combines topics from a wide range of disciplines, such as Differential centrifugation, Cytosol, Endoplasmic reticulum, Cytochrome P450 and Methylcholanthrene. His Glutathione reductase research integrates issues from GPX4 and GPX1.
Joseph W. DePierre mainly investigates Internal medicine, Endocrinology, Immune system, Spleen and Biochemistry. His work on Adipose tissue, Peroxisome Proliferation, Atrophy and Tumor necrosis factor alpha as part of general Internal medicine study is frequently linked to Peroxisome proliferator-activated receptor alpha, therefore connecting diverse disciplines of science. His work on Liver injury as part of general Endocrinology research is often related to Perfluorooctane, thus linking different fields of science.
His Cytosol, Microsome, Corpus luteum, Apoptosis and Peroxisome study are his primary interests in Biochemistry. His Cytosol research also works with subjects such as
Joseph W. DePierre spends much of his time researching Internal medicine, Endocrinology, Spleen, Immune system and Acquired immune system. Joseph W. DePierre integrates Internal medicine and Perfluorooctane in his research. His work carried out in the field of Acquired immune system brings together such families of science as Lipopolysaccharide and Innate immune system.
His research in Lipopolysaccharide intersects with topics in Tumor necrosis factor alpha, Inflammation, Interleukin 6, Cytokine and Granulocyte. His research investigates the connection with Splenocyte and areas like Thymocyte which intersect with concerns in Fatty acid metabolism and Nafenopin. The study incorporates disciplines such as Adipose tissue and Peroxisome Proliferation in addition to Atrophy.
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Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver.
Maria S. Moron;Joseph W. Depierre;Bengt Mannervik.
Biochimica et Biophysica Acta (1979)
ENZYME TOPOLOGY OF INTRACELLULAR MEMBRANES
Joseph W. DePierre;Lars Ernster.
Annual Review of Biochemistry (1977)
Tricyclic antidepressants inhibit IL-6, IL-1β and TNF-α release in human blood monocytes and IL-2 and interferon-γ in T cells
Zhenlei Xia;Joseph W. Depierre;Lennart Nässberger.
Microsomal glutathione transferase. Purification in unactivated form and further characterization of the activation process, substrate specificity and amino acid composition.
Ralf Morgenstern;Joseph W. DePIERRE.
FEBS Journal (1983)
A reliable, sensitive, and convenient radioactive assay for benzpyrene monooxygenase.
J.W. DePierre;M.S. Moron;K.A.M. Johannesen;L. Ernster.
Analytical Biochemistry (1975)
Microsomal glutathione S-transferase. Purification, initial characterization and demonstration that it is not identical to the cytosolic glutathione S-transferases A, B and C.
Ralf Morgenstern;Claes Guthenberg;Joseph W. Depierre.
FEBS Journal (2005)
Measurement of cytochrome P-450 in the presence of large amounts of contaminating hemoglobin and methemoglobin.
Karin A.M. Johannesen;Joseph W. DePierre.
Analytical Biochemistry (1978)
Microsomal epoxide hydrolase. Properties, regulation and function
Janeric Seidegård;Joseph W. DePierre.
Biochimica et Biophysica Acta (1983)
Activation of microsomal glutathione S-transferase activity by sulfhydryl reagents
Ralf Morgenstern;Joseph W. Depierre;Lars Ernster.
Biochemical and Biophysical Research Communications (1979)
The metabolism of polycyclic hydrocarbons and its relationship to cancer
Joseph W. DePierre;Lars Ernster.
Biochimica et Biophysica Acta (1978)
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