What is he best known for?
The fields of study he is best known for:
His main research concerns Biochemistry, Microsome, Glutathione, Internal medicine and Endocrinology.
As part of one scientific family, Joseph W. DePierre deals mainly with the area of Biochemistry, narrowing it down to issues related to the Molecular biology, and often Programmed cell death and Apoptosis.
His work in Glutathione reductase and Glutathione S-transferase are all subfields of Glutathione research.
His work in Glutathione reductase addresses issues such as GPX3, which are connected to fields such as GPX1.
In general Internal medicine, his work in Spleen, Cytokine and Inflammation is often linked to Imipramine linking many areas of study.
His Endocrinology research is multidisciplinary, incorporating perspectives in Viability assay, Bcl-xL, Mitochondrion and Pharmacology.
His most cited work include:
- Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. (3060 citations)
- ENZYME TOPOLOGY OF INTRACELLULAR MEMBRANES (350 citations)
- Tricyclic antidepressants inhibit IL-6, IL-1β and TNF-α release in human blood monocytes and IL-2 and interferon-γ in T cells (270 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Biochemistry, Internal medicine, Endocrinology, Microsome and Enzyme.
His Biochemistry study frequently links to adjacent areas such as Molecular biology.
He works mostly in the field of Internal medicine, limiting it down to concerns involving Immune system and, occasionally, Antibody and Inflammation.
Joseph W. DePierre has researched Endocrinology in several fields, including Protein subunit and Gentamicin.
His Microsome study combines topics from a wide range of disciplines, such as Differential centrifugation, Cytosol, Endoplasmic reticulum, Cytochrome P450 and Methylcholanthrene.
His Glutathione reductase research integrates issues from GPX4 and GPX1.
He most often published in these fields:
- Biochemistry (54.50%)
- Internal medicine (27.49%)
- Endocrinology (27.49%)
What were the highlights of his more recent work (between 2000-2020)?
- Internal medicine (27.49%)
- Endocrinology (27.49%)
- Immune system (5.69%)
In recent papers he was focusing on the following fields of study:
Joseph W. DePierre mainly investigates Internal medicine, Endocrinology, Immune system, Spleen and Biochemistry.
His work on Adipose tissue, Peroxisome Proliferation, Atrophy and Tumor necrosis factor alpha as part of general Internal medicine study is frequently linked to Peroxisome proliferator-activated receptor alpha, therefore connecting diverse disciplines of science.
His work on Liver injury as part of general Endocrinology research is often related to Perfluorooctane, thus linking different fields of science.
His Cytosol, Microsome, Corpus luteum, Apoptosis and Peroxisome study are his primary interests in Biochemistry.
His Cytosol research also works with subjects such as
- Mitochondrion which is related to area like Fatty acid metabolism,
- Sedimentation coefficient and related Glutathione.
His Glutathione study which covers Reactive oxygen species that intersects with Molecular biology.
Between 2000 and 2020, his most popular works were:
- Microsomal glutathione S-transferase. Purification, initial characterization and demonstration that it is not identical to the cytosolic glutathione S-transferases A, B and C. (213 citations)
- Potent suppression of the adaptive immune response in mice upon dietary exposure to the potent peroxisome proliferator, perfluorooctanoic acid (130 citations)
- Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid. (121 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Gene
- Organic chemistry
Joseph W. DePierre spends much of his time researching Internal medicine, Endocrinology, Spleen, Immune system and Acquired immune system.
Joseph W. DePierre integrates Internal medicine and Perfluorooctane in his research.
His work carried out in the field of Acquired immune system brings together such families of science as Lipopolysaccharide and Innate immune system.
His research in Lipopolysaccharide intersects with topics in Tumor necrosis factor alpha, Inflammation, Interleukin 6, Cytokine and Granulocyte.
His research investigates the connection with Splenocyte and areas like Thymocyte which intersect with concerns in Fatty acid metabolism and Nafenopin.
The study incorporates disciplines such as Adipose tissue and Peroxisome Proliferation in addition to Atrophy.
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