Donald R. Buhler

Overview

Best Publications

• Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines.

  C.L. Miranda;J.F. Stevens;A. Helmrich;M.C. Henderson

  593
  Citations

• Antioxidant and Prooxidant Actions of Prenylated and Nonprenylated Chalcones and Flavanones in Vitro

  Cristobal L. Miranda;Jan F. Stevens;Vadim Ivanov;Mark Mccall

  550
  Citations

• Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression

  Siew Hong Lam;Yi Lian Wu;Vinsensius B Vega;Lance D Miller

  343
  Citations

• Status and opportunities for genomics research with rainbow trout.

  Gary H. Thorgaard;George S. Bailey;David Williams;Donald R. Buhler

  325
  Citations

• In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus

  M.C. Henderson;C.L. Miranda;J.F. Stevens;M.L. Deinzer

  324
  Citations

• Prenylated chalcones and flavanones as inducers of quinone reductase in mouse Hepa 1c1c7 cells

  C.L Miranda;G.L.M Aponso;J.F Stevens;M.L Deinzer

  246
  Citations

• Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-κB and Akt as targets

  Adriana Albini;Raffaella Dell'Eva;Roberta Vené;Nicoletta Ferrari

  241
  Citations

• Rainbow trout cytochrome P450s: purification, molecular aspects, metabolic activity, induction and role in environmental monitoring

  Donald R Buhler;Jun-Lan Wang-Buhler

  233
  Citations

• Constitutive and xenobiotics-induced expression of a novel CYP3A gene from zebrafish larva

  Hua-Pin Tseng;Tzong-Hsiung Hseu;Donald R Buhler;Wen-Der Wang

  224
  Citations

• The role of biotransformation in the toxicity of chemicals

  Donald R. Buhler;David E. Williams

  218
  Citations

• Benzo[a]pyrene-hydroxylase catalyzed by purified isozymes of cytochrome P-450 from β-naphthoflavone-fed rainbow trout

  David E. Williams;Donald R. Buhler

  174
  Citations

• Influence of the Ah locus on the humoral immunotoxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: evidence for Ah-receptor-dependent and Ah-receptor-independent mechanisms of immunosuppression.

  N.I. Kerkvliet;L.B. Steppan;J.A. Brauner;J.A. Deyo

  164
  Citations

• Evaluation of chemicals as inhibitors of trout cytochrome P450s.

  C.L. Miranda;M.C. Henderson;D.R. Buhler

  163
  Citations

• Role of the Ah locus in suppression of cytotoxic T lymphocyte activity by halogenated aromatic hydrocarbons (PCBs and TCDD): structure-activity relationships and effects in C57Bl/6 mice congenic at the Ah locus.

  N I Kerkvliet;L Baecher-Steppan;B B Smith;J A Youngberg

  160
  Citations

• Chemistry and biology of hop flavonoids.

  Jan F. Stevens;Cristobal L. Miranda;Donald R. Buhler;Max L. Deinzer

  158
  Citations

• Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout

  C.L. Miranda;J.-L. Wang;M.C. Henderson;D.R. Buhler

  154
  Citations

• Prenylflavonoids from Hops Inhibit the Metabolic Activation of the Carcinogenic Heterocyclic Amine 2-Amino-3-methylimidazo[4,5-f]quinoline, Mediated by cDNA-Expressed Human CYP1A2

  Cristobal L. Miranda;Yea-Huey Yang;Marilyn C. Henderson;Jan F. Stevens

  153
  Citations

• Immunochemical cross-reactivity ofβ-naphthoflavone-inducible cytochrome P450 (P450IA) in liver microsomes from different fish species and rat.

  Anders Goksøyr;Tommy Andersson;Donald R. Buhler;John J. Stegeman

  149
  Citations

• Influence of prenylated and non-prenylated flavonoids on liver microsomal lipid peroxidation and oxidative injury in rat hepatocytes

  R.J. Rodriguez;C.L. Miranda;J.F. Stevens;M.L. Deinzer

  145
  Citations

• Bioactivation and detoxication of the pyrrolizidine alkaloid senecionine by cytochrome P-450 enzymes in rat liver.

  D E Williams;R L Reed;B Kedzierski;G A Dannan

  143
  Citations