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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
12547
World Ranking
13772
National Ranking
248

Overview

Michael Arand is affiliated with the University of Zurich in Switzerland and has contributed extensively to the field of medicine, with a focus on several key subfields including biomedical engineering, molecular biology, pharmacology, cancer research, and oncology.

Their research touches on a variety of topics such as:

  • Drug Transport and Resistance Mechanisms
  • Drug-Induced Hepatotoxicity and Protection
  • Carcinogens and Genotoxicity Assessment
  • Photoacoustic and Ultrasonic Imaging
  • Pharmacological Effects and Toxicity Studies
  • Virus-based gene therapy research
  • Eicosanoids and Hypertension Pharmacology

Michael Arand has published in several venues, with frequent contributions to PUBLISSO and Archives of Toxicology, alongside publications in Nature Communications, Science Advances, and Toxicology in Vitro.

Notable recent papers include:

  • Mode of action-based risk assessment of genotoxic carcinogens, 2020, Archives of Toxicology
  • Deep optoacoustic localization microangiography of ischemic stroke in mice, 2023, Nature Communications
  • High-resolution fluorescence-guided transcranial ultrasound mapping in the live mouse brain, 2021, Science Advances
  • Novel insights into bile acid detoxification via CYP, UGT and SULT enzymes, 2022, Toxicology in Vitro
  • Correction to: Mode of action-based risk assessment of genotoxic carcinogens, 2020, Archives of Toxicology

Throughout their career, Michael Arand has collaborated frequently with several researchers, including:

  • A. Hartwig
  • Ivonne M.C.M. Rietjens
  • Gerhard Eisenbrand
  • Bruno Weber
  • Anne Marowsky

Best Publications

  • Simultaneous Humoral and Cellular Immune Response against Cancer–Testis Antigen NY-ESO-1: Definition of Human Histocompatibility Leukocyte Antigen (HLA)-A2–binding Peptide Epitopes

    Elke Jäger;Yao Tseng Chen;Jan W. Drijfhout;Julia Karbach

  • A Survey of the Humoral Immune Response of Cancer Patients to a Panel of Human Tumor Antigens

    Elisabeth Stockert;Elke Jäger;Yao-Tseng Chen;Matthew J. Scanlan

  • Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers.

    Elke Jäger;Sacha Gnjatic;Yasuhiro Nagata;Elisabeth Stockert

  • Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses

    E Jäger;Y Nagata;S Gnjatic;H Wada

  • A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms.

    Michael Arand;Roland Mühlbauer;Jan Hengstler;Elke Jäger

  • Immunoselection in vivo : independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma

    Elke Jäger;Mark Ringhoffer;Michael Altmannsberger;Michael Arand

  • Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic-T-cell responses: evidence for immunoselection of antigen-loss variants in vivo.

    Elke Jäger;Mark Ringhoffer;Julia Karbach;Michael Arand

  • Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo

    Elke Jäger;Mark Ringhoffer;Hans Peter Dienes;Michael Arand

  • Identification of Ny-Eso-1 Epitopes Presented by Human Histocompatibility Antigen (Hla)-Drb4*0101–0103 and Recognized by Cd4+T Lymphocytes of Patients with Ny-Eso-1–Expressing Melanoma

    Elke Jäger;Dirk Jäger;Julia Karbach;Yao-Tseng Chen;Yao-Tseng Chen

  • Generation of cytotoxic T‐cell responses with synthetic melanoma‐associated peptides in vivo: Implications for tumor vaccines with melanoma‐associated antigens

    Elke Jäeger;Helga Bernhard;Pedro Romero;Mark Ringhoffer

  • Humoral immune responses of cancer patients against "Cancer-Testis" antigen NY-ESO-1: correlation with clinical events.

    Elke Jäger;Elisabeth Stockert;Zacharias Zidianakis;Yao-Tseng Chen;Yao-Tseng Chen

  • Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.

    J. G. Hengstler;M. Arand;M. E. Herrero;F. Oesch

  • Mammalian epoxide hydrolases in xenobiotic metabolism and signalling

    Martina Decker;Michael Arand;Annette Cronin

  • Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases.

    J Zou;B M Hallberg;T Bergfors;F Oesch

  • Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins Implication for the potential catalytic mechanism of enzymatic epoxide hydrolysis

    Michael Arand;David F. Grant;Jeffrey K. Beetham;Thomas Friedberg

  • Aryl hydrocarbon receptor activation by cAMP vs. dioxin : Divergent signaling pathways

    Barbara Oesch-Bartlomowicz;Andrea Huelster;Oliver Wiss;Patricia Antoniou-Lipfert

  • Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution.

    Manfred T. Reetz;Claudia Torre;Andreas Eipper;Renate Lohmer

  • The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase

    Annette Cronin;Sherry Mowbray;Heike Dürk;Shirli Homburg

  • Gene evolution of epoxide hydrolases and recommended nomenclature.

    Jeffrey K. Beetham;David Grant;Michael Arand;Joan Garbarino

  • Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site

    Michael Arand;B.Martin Hallberg;Jinyu Zou;Terese Bergfors

Frequent Co-Authors

Franz Oesch
Franz Oesch Johannes Gutenberg University of Mainz
Jan G. Hengstler
Jan G. Hengstler TU Dortmund University
Alexander Knuth
Alexander Knuth University of Zurich
Elke Jäger
Elke Jäger Goethe University Frankfurt
Yao-Tseng Chen
Yao-Tseng Chen Cornell University
Dirk Jäger
Dirk Jäger Heidelberg University
Sherry L. Mowbray
Sherry L. Mowbray Uppsala University
Roland Furstoss
Roland Furstoss Centre national de la recherche scientifique, CNRS
Lloyd J. Old
Lloyd J. Old Ludwig Cancer Research
Bruce D. Hammock
Bruce D. Hammock University of California, Davis

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