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Medicine

D-Index
78
Citations
26660
World Ranking
17911
National Ranking
942

Overview

Elke Jäger is affiliated with Goethe University Frankfurt in Germany. Their research primarily spans the field of Medicine, with particular focus on Oncology, Immunology, and Infectious Diseases. Subfields of study also include Molecular Biology and Surgery, reflecting a multidisciplinary approach to medical science.

The scientist's work covers several main research topics, including:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Cancer survivorship and care
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Immune Cell Function and Interaction

Elke Jäger has published frequently in several scientific venues. The most common publication venues include:

  • Annals of Oncology
  • Medicine & Science in Sports & Exercise
  • Leukemia
  • TumorDiagnostik & Therapie
  • Nature Immunology

Their recent notable papers are:

  • "SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition", 2020, Nature Immunology
  • "A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity", 2021, Nature
  • "A Frameshift Peptide Neoantigen-Based Vaccine for Mismatch Repair-Deficient Cancers: A Phase I/IIa Clinical Trial", 2020, Clinical Cancer Research
  • "Immune signatures predict development of autoimmune toxicity in patients with cancer treated with immune checkpoint inhibitors", 2023, Med
  • "High-risk additional chromosomal abnormalities at low blast counts herald death by CML", 2020, Leukemia

Frequent collaborators of Elke Jäger include:

  • Julia Karbach
  • Dragan Kiselicki
  • Akin Atmaca
  • Katharina Graf
  • Juliane S. Walz

Best Publications

  • Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial.

    Salah-Eddin Al-Batran;Nils Homann;Claudia Pauligk;Thorsten O Goetze

  • Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1

    M Marchand;N van Baren;N van Baren;P Weynants;P Weynants;V Brichard;V Brichard;V Brichard

  • Phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil, leucovorin plus either oxaliplatin or cisplatin: a study of the Arbeitsgemeinschaft Internistische Onkologie

    Salah-Eddin Al-Batran;Joerg Thomas Hartmann;Stephan Probst;Harald Schmalenberg

  • Simultaneous Humoral and Cellular Immune Response against Cancer–Testis Antigen NY-ESO-1: Definition of Human Histocompatibility Leukocyte Antigen (HLA)-A2–binding Peptide Epitopes

    Elke Jäger;Yao Tseng Chen;Jan W. Drijfhout;Julia Karbach

  • A Survey of the Humoral Immune Response of Cancer Patients to a Panel of Human Tumor Antigens

    Elisabeth Stockert;Elke Jäger;Yao-Tseng Chen;Matthew J. Scanlan

  • Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial.

    Salah-Eddin Al-Batran;Ralf D Hofheinz;Claudia Pauligk;Hans-Georg Kopp

  • Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: Correlation with antibody responses

    Sacha Gnjatic;Djordje Atanackovic;Elke Jäger;Mitsutoshi Matsuo

  • Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans

    Daisuke Sugiyama;Hiroyoshi Nishikawa;Yuka Maeda;Megumi Nishioka

  • SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition.

    Annika Nelde;Tatjana Bilich;Jonas S. Heitmann;Yacine Maringer

  • Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers.

    Elke Jäger;Sacha Gnjatic;Yasuhiro Nagata;Elisabeth Stockert

  • Tumor regression responses in melanoma patients treated with a peptide encoded by gene MAGE-3

    M Marchand;P Weynants;E Rankin;F Arienti

  • Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses

    E Jäger;Y Nagata;S Gnjatic;H Wada

  • NY-ESO-1: review of an immunogenic tumor antigen.

    Sacha Gnjatic;Hiroyoshi Nishikawa;Achim A Jungbluth;Ali O Güre

  • A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms.

    Michael Arand;Roland Mühlbauer;Jan Hengstler;Elke Jäger

  • Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library

    Yao-Tseng Chen;Ali O. Güre;Solam Tsang;Elisabeth Stockert

  • Immunoselection in vivo : independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma

    Elke Jäger;Mark Ringhoffer;Michael Altmannsberger;Michael Arand

  • Effect of Neoadjuvant Chemotherapy Followed by Surgical Resection on Survival in Patients With Limited Metastatic Gastric or Gastroesophageal Junction Cancer: The AIO-FLOT3 Trial

    Salah-Eddin Al-Batran;Nils Homann;Claudia Pauligk;Gerald Illerhaus

  • Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic-T-cell responses: evidence for immunoselection of antigen-loss variants in vivo.

    Elke Jäger;Mark Ringhoffer;Julia Karbach;Michael Arand

  • Prognosis of metastatic gastric and gastroesophageal junction cancer by HER2 status: a European and USA International collaborative analysis

    Y.Y. Janjigian;D. Werner;C. Pauligk;K. Steinmetz

  • Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo

    Elke Jäger;Mark Ringhoffer;Hans Peter Dienes;Michael Arand

Frequent Co-Authors

Alexander Knuth
Alexander Knuth University of Zurich
Dirk Jäger
Dirk Jäger Heidelberg University
Lloyd J. Old
Lloyd J. Old Ludwig Cancer Research
Yao-Tseng Chen
Yao-Tseng Chen Cornell University
Markus Maeurer
Markus Maeurer Champalimaud Foundation
Sacha Gnjatic
Sacha Gnjatic Icahn School of Medicine at Mount Sinai
Gerd Ritter
Gerd Ritter Memorial Sloan Kettering Cancer Center
Elisabeth Stockert
Elisabeth Stockert Memorial Sloan Kettering Cancer Center
Michael Arand
Michael Arand University of Zurich
Matthias Kloor
Matthias Kloor University Hospital Heidelberg

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