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D-Index & Metrics

Microbiology

D-Index
49
Citations
14502
World Ranking
4517
National Ranking
309

Overview

Dirk Jäger is affiliated with Heidelberg University in Germany and has an extensive publication record primarily focused on medicine and biochemistry, genetics, and molecular biology. Their research spans various subfields including oncology, molecular biology, pulmonary and respiratory medicine, cancer research, and immunology.

The scientist's recent publications demonstrate a focus on cancer and immunotherapy. Notable papers include:

  • Pan-cancer image-based detection of clinically actionable genetic alterations, 2020, Nature Cancer
  • Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction, 2020, Cell
  • Caring for patients with cancer in the COVID-19 era, 2020, Nature Medicine
  • Impact of 68Ga-FAPI PET/CT Imaging on the Therapeutic Management of Primary and Recurrent Pancreatic Ductal Adenocarcinomas, 2020, Journal of Nuclear Medicine
  • Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC), 2020, European Journal of Heart Failure

Frequent co-authors in their research include:

  • Christoph Springfeld
  • Stefan Fröhling
  • Inka Zörnig
  • Albrecht Stenzinger
  • Stefanie Zschäbitz

Frequent publication venues reflect the scientist's engagement in oncology and molecular biology focused journals, including:

  • Cancers
  • Frontiers in Immunology
  • Frontiers in Oncology
  • Annals of Oncology
  • Nature Cancer

Their work covers a range of main research topics:

  • Cancer Immunotherapy and Biomarkers
  • Pancreatic and Hepatic Oncology Research
  • CAR-T cell therapy research
  • Cancer Genomics and Diagnostics
  • Immunotherapy and Immune Responses
  • Renal cell carcinoma treatment
  • Virus-based gene therapy research

The breadth of Dirk Jäger's research encompasses applied and translational aspects of cancer biology, immunotherapeutic strategies, and diagnostic advancements. Their collaborations and publication record indicate active participation in multidisciplinary cancer research with a significant clinical perspective.

Best Publications

  • Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial

    Scott J. Antonia;José A. López-Martin;Johanna Bendell;Patrick A. Ott

  • Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer.

    Jakob Nikolas Kather;Alexander T. Pearson;Niels Halama;Dirk Jäger

  • Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy.

    Felix Klug;Hridayesh Prakash;Hridayesh Prakash;Hridayesh Prakash;Peter E. Huber;Tobias Seibel

  • Simultaneous Humoral and Cellular Immune Response against Cancer–Testis Antigen NY-ESO-1: Definition of Human Histocompatibility Leukocyte Antigen (HLA)-A2–binding Peptide Epitopes

    Elke Jäger;Yao Tseng Chen;Jan W. Drijfhout;Julia Karbach

  • Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability–High/Mismatch Repair–Deficient Metastatic Colorectal Cancer: KEYNOTE-164

    Dung T Le;Tae Won Kim;Eric Van Cutsem;Ravit Geva

  • Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers.

    Elke Jäger;Sacha Gnjatic;Yasuhiro Nagata;Elisabeth Stockert

  • Pan-cancer image-based detection of clinically actionable genetic alterations

    Jakob Nikolas Kather;Jakob Nikolas Kather;Lara R. Heij;Lara R. Heij;Heike I. Grabsch;Heike I. Grabsch;Chiara Loeffler

  • The Leukotriene C4 Transporter MRP1 Regulates CCL19 (MIP-3β, ELC)–Dependent Mobilization of Dendritic Cells to Lymph Nodes

    Davide F Robbiani;Rick A Finch;Dirk Jäger;William A Muller

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses

    E Jäger;Y Nagata;S Gnjatic;H Wada

  • Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction

    Daniel K. Wells;Marit M. van Buuren;Kristen K. Dang;Vanessa M. Hubbard-Lucey

  • Immunoselection in vivo : independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma

    Elke Jäger;Mark Ringhoffer;Michael Altmannsberger;Michael Arand

  • Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo

    Elke Jäger;Mark Ringhoffer;Hans Peter Dienes;Michael Arand

  • Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer.

    R.-D. Hofheinz;S.-E. al-Batran;F. Hartmann;G. Hartung

  • Caring for patients with cancer in the COVID-19 era.

    Joris van de Haar;Louisa R. Hoes;Charlotte E. Coles;Kenneth Seamon

  • Identification of Ny-Eso-1 Epitopes Presented by Human Histocompatibility Antigen (Hla)-Drb4*0101–0103 and Recognized by Cd4+T Lymphocytes of Patients with Ny-Eso-1–Expressing Melanoma

    Elke Jäger;Dirk Jäger;Julia Karbach;Yao-Tseng Chen;Yao-Tseng Chen

  • Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors

    Sylvie Rusakiewicz;Michaela Semeraro;Matthieu Sarabi;Mélanie Desbois

  • CTLA-4 and PD-L1 Checkpoint Blockade Enhances Oncolytic Measles Virus Therapy

    Christine E Engeland;Christine E Engeland;Christian Grossardt;Rūta Veinalde;Sascha Bossow

  • Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer.

    Ali O. Güre;Elisabeth Stockert;Matthew J. Scanlan;Roger S. Keresztes

  • Humoral immune responses of cancer patients against "Cancer-Testis" antigen NY-ESO-1: correlation with clinical events.

    Elke Jäger;Elisabeth Stockert;Zacharias Zidianakis;Yao-Tseng Chen;Yao-Tseng Chen

  • Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients.

    Elke Jäger;Julia Karbach;Sacha Gnjatic;Antje Neumann

  • Topography of cancer-associated immune cells in human solid tumors

    Jakob Nikolas Kather;Meggy Suarez-Carmona;Meggy Suarez-Carmona;Pornpimol Charoentong;Pornpimol Charoentong;Cleo-Aron Weis

  • Seromic profiling of ovarian and pancreatic cancer

    Sacha Gnjatic;Erika Ritter;Markus W. Büchler;Nathalia A. Giese

  • Prognosis of breast cancer molecular subtypes in routine clinical care: A large prospective cohort study

    André Hennigs;Fabian Riedel;Adam Gondos;Peter Sinn

  • Immune responses to tumour antigens: implications for antigen specific immunotherapy of cancer.

    Unknown

  • Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8

    Unknown

  • Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue-specific ING1 transcripts and a homologue gene

    Dirk Jäger;Elisabeth Stockert;Matthew J. Scanlan;Ali O. Güre

  • Consensus nomenclature for CD8+ T cell phenotypes in cancer

    Lionel Apetoh;Mark J. Smyth;Charles G. Drake;Jean Pierre Abastado

Frequent Co-Authors

Alexander Knuth
Alexander Knuth University of Zurich
Elke Jäger
Elke Jäger Goethe University Frankfurt
Yao-Tseng Chen
Yao-Tseng Chen Cornell University
Markus W. Büchler
Markus W. Büchler Champalimaud Foundation
Lloyd J. Old
Lloyd J. Old Ludwig Cancer Research
Hanno Glimm
Hanno Glimm TU Dresden
Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
Benedikt Brors
Benedikt Brors German Cancer Research Center
Uwe Haberkorn
Uwe Haberkorn Heidelberg University
Elisabeth Stockert
Elisabeth Stockert Memorial Sloan Kettering Cancer Center

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