World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
93
Citations
35138
World Ranking
10807
National Ranking
5561

Overview

Yao-Tseng Chen is affiliated with Cornell University in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research output includes 28 publications related to biochemistry, genetics, and molecular biology, alongside 21 publications in medicine. Key subfields of study encompass molecular biology, epidemiology, cancer research, oncology, and pediatrics, perinatology, and child health.

The scientist's work frequently appears in journals such as Cancer Research, Cancer Letters, bioRxiv (Cold Spring Harbor Laboratory), Cancer Science, and NAR Cancer. The most common publication venues include:

  • Cancer Research
  • Cancer Letters
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Science
  • NAR Cancer

Their main topics of investigation cover neuroendocrine tumor research advances, cancer related to hypoxia and metabolism, epigenetics and DNA methylation, heme oxygenase-1 and carbon monoxide signaling, lung cancer research, cancer-related gene regulation, and neonatal health and biochemistry. These tenets reflect cross-disciplinary approaches spanning molecular mechanisms to clinical oncology.

Yao-Tseng Chen has coauthored multiple papers with frequent collaborators including Zhengming Chen, Yi-Chieh Nancy Du, Tiantian Zhang, Dunrui Wang, and George Zhang. Collaborations with these researchers have contributed to advances across cancer biology and molecular oncology.

Important recent publications include:

  • "Low-dose carbon monoxide suppresses metastatic progression of disseminated cancer cells," 2022, Cancer Letters
  • "High levels of truncated RHAMM cooperate with dysfunctional p53 to accelerate the progression of pancreatic cancer," 2021, Cancer Letters
  • "Characterizing and classifying neuroendocrine neoplasms through microRNA sequencing and data mining," 2020, NAR Cancer
  • "Classifying Lung Neuroendocrine Neoplasms through MicroRNA Sequence Data Mining," 2020, Cancers
  • "RHAMMB-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment," 2021, Molecular Therapy - Oncolytics

The research contributions focus notably on cancer types including neuroendocrine tumors and pancreatic cancer, with investigations into molecular pathways involving hypoxia, metabolism, gene regulation, and microRNA-based classification. The roles of heme oxygenase-1 and carbon monoxide are also a notable focus, linking molecular findings to potential therapeutic mechanisms.

Best Publications

  • Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

    Eiichi Sato;Sara H. Olson;Jiyoung Ahn;Brian Bundy

  • Cancer/testis antigens, gametogenesis and cancer.

    Andrew J. G. Simpson;Otavia L. Caballero;Achim Jungbluth;Yao-Tseng Chen

  • A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening

    Yao-Tseng Chen;Matthew J. Scanlan;Ugur Sahin;Özlem Türeci

  • Cancer/testis antigens: an expanding family of targets for cancer immunotherapy.

    Matthew J. Scanlan.;Ali O. Gure.;Achim A. Jungbluth.;Lloyd J. Old.

  • Simultaneous Humoral and Cellular Immune Response against Cancer–Testis Antigen NY-ESO-1: Definition of Human Histocompatibility Leukocyte Antigen (HLA)-A2–binding Peptide Epitopes

    Elke Jäger;Yao Tseng Chen;Jan W. Drijfhout;Julia Karbach

  • A Survey of the Humoral Immune Response of Cancer Patients to a Panel of Human Tumor Antigens

    Elisabeth Stockert;Elke Jäger;Yao-Tseng Chen;Matthew J. Scanlan

  • Cancer/testis (CT) antigens: potential targets for immunotherapy.

    Otavia L. Caballero;Yao Tseng Chen

  • Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: Correlation with antibody responses

    Sacha Gnjatic;Djordje Atanackovic;Elke Jäger;Mitsutoshi Matsuo

  • Immunohistochemical analysis of NY‐ESO‐1 antigen expression in normal and malignant human tissues

    Achim A. Jungbluth;Yao-Tseng Chen;Elisabeth Stockert;Klaus J. Busam

  • Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers.

    Elke Jäger;Sacha Gnjatic;Yasuhiro Nagata;Elisabeth Stockert

  • New paths in human cancer serology.

    Lloyd J. Old;Yao-Tseng Chen

  • Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses

    E Jäger;Y Nagata;S Gnjatic;H Wada

  • NY-ESO-1: review of an immunogenic tumor antigen.

    Sacha Gnjatic;Hiroyoshi Nishikawa;Achim A Jungbluth;Ali O Güre

  • Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4(+) and CD8(+) T cell responses in humans.

    Ian D. Davis;Weisan Chen;Heather Jackson;Phillip Parente;Phillip Parente

  • Characterization of human colon cancer antigens recognized by autologous antibodies

    Matthew J. Scanlan;Yao-Tseng Chen;Yao-Tseng Chen;Barbara Williamson;Ali O. Gure

  • CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens

    Luiz Gonzaga Almeida;Noboru J. Sakabe;Alice R. deOliveira;Maria Cristina C. Silva

  • Genome-wide analysis of cancer/testis gene expression

    Oliver Hofmann;Oliver Hofmann;Otavia L. Caballero;Brian J. Stevenson;Brian J. Stevenson;Yao Tseng Chen

  • Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library

    Yao-Tseng Chen;Ali O. Güre;Solam Tsang;Elisabeth Stockert

  • Identification of Ny-Eso-1 Epitopes Presented by Human Histocompatibility Antigen (Hla)-Drb4*0101–0103 and Recognized by Cd4+T Lymphocytes of Patients with Ny-Eso-1–Expressing Melanoma

    Elke Jäger;Dirk Jäger;Julia Karbach;Yao-Tseng Chen;Yao-Tseng Chen

  • SSX: A multigene family with several members transcribed in normal testis and human cancer

    Ali O. Gure;Özlem Türeci;Ugur Sahin;Solam Tsang

Frequent Co-Authors

Lloyd J. Old
Lloyd J. Old Ludwig Cancer Research
Elisabeth Stockert
Elisabeth Stockert Memorial Sloan Kettering Cancer Center
Achim A. Jungbluth
Achim A. Jungbluth Memorial Sloan Kettering Cancer Center
Alexander Knuth
Alexander Knuth University of Zurich
Sacha Gnjatic
Sacha Gnjatic Icahn School of Medicine at Mount Sinai
Gerd Ritter
Gerd Ritter Memorial Sloan Kettering Cancer Center
Dirk Jäger
Dirk Jäger Heidelberg University
Elke Jäger
Elke Jäger Goethe University Frankfurt
Nasser K. Altorki
Nasser K. Altorki Cornell University
Andrew J.G. Simpson
Andrew J.G. Simpson Ludwig Cancer Research

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