World's Best Scientists 2026 revealed!

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Immunology

D-Index
99
Citations
46072
World Ranking
738
National Ranking
419

Medicine

D-Index
99
Citations
46072
World Ranking
8465
National Ranking
4373

Overview

Sacha Gnjatic is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research spans multiple fields including Medicine and Biochemistry, Genetics and Molecular Biology. Their work notably intersects oncology, immunology, molecular biology, infectious diseases, and hematology.

The scientist's research topics cover a broad range of subjects related to immune responses and cancer treatment, including:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Multiple Myeloma Research and Treatments
  • COVID-19 Clinical Research Studies
  • Cancer Genomics and Diagnostics
  • SARS-CoV-2 and COVID-19 Research
  • CAR-T cell therapy research

Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Clinical Lymphoma Myeloma & Leukemia
  • Gastroenterology
  • Journal for ImmunoTherapy of Cancer

Some of the recent significant papers authored or coauthored by Sacha Gnjatic are:

  • "An inflammatory cytokine signature predicts COVID-19 severity and survival," 2020, Nature Medicine
  • "PD-L1 as a biomarker of response to immune-checkpoint inhibitors," 2021, Nature Reviews Clinical Oncology
  • "Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)," 2020, Cell
  • "Intratumoral dendritic cell-CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma," 2023, Nature Medicine
  • "The Society for Immunotherapy of Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation," 2020, Journal for ImmunoTherapy of Cancer

Collaborations feature notable frequent coauthors, including:

  • Seunghee Kim-Schulze
  • Edgar Gonzalez-Kozlova
  • Miriam Mérad
  • Diane M. Del Valle
  • Thomas U. Marron

Best Publications

  • Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

    Eiichi Sato;Sara H. Olson;Jiyoung Ahn;Brian Bundy

  • An inflammatory cytokine signature predicts COVID-19 severity and survival.

    Diane Marie Del Valle;Seunghee Kim-Schulze;Hsin-Hui Huang;Noam D. Beckmann

  • Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

    Michael A. Postow;Margaret K. Callahan;Margaret K. Callahan;Christopher A. Barker;Christopher A. Barker;Yoshiya Yamada;Yoshiya Yamada

  • PD-L1 as a biomarker of response to immune-checkpoint inhibitors

    Deborah Blythe Doroshow;Sheena Bhalla;Mary Beth Beasley;Lynette M. Sholl

  • Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.

    Vinod P. Balachandran;Marta Łuksza;Julia N. Zhao;Vladimir Makarov

  • Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

    Hélène Salmon;Juliana Idoyaga;Adeeb Rahman;Marylène Leboeuf

  • Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses.

    Yonit Lavin;Soma Kobayashi;Andrew Leader;El-ad David Amir

  • Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1.

    Naomi N. Hunder;Herschel Wallen;Jianhong Cao;Deborah W. Hendricks

  • Tumor-infiltrating NY-ESO-1–specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer

    Junko Matsuzaki;Sacha Gnjatic;Paulette Mhawech-Fauceglia;Amy Beck

  • Cancer classification using the Immunoscore: a worldwide task force

    Jérôme Galon;Franck Pagès;Francesco M Marincola;Francesco M Marincola;Helen K Angell;Helen K Angell

  • Radiotherapy induces responses of lung cancer to CTLA-4 blockade

    Silvia C. Formenti;Nils Petter Rudqvist;Encouse Golden;Encouse Golden;Benjamin Cooper

  • Single-cell immune landscape of human atherosclerotic plaques

    Dawn M Fernandez;Adeeb H Rahman;Nicolas F Fernandez;Aleksey Chudnovskiy

  • Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.

    Jerome C. Martin;Christie Chang;Gilles Boschetti;Ryan Ungaro

  • Presence of B Cells in Tertiary Lymphoid Structures Is Associated with a Protective Immunity in Patients with Lung Cancer

    Claire Germain;Sacha Gnjatic;Fella Tamzalit;Samantha Knockaert

  • Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: Correlation with antibody responses

    Sacha Gnjatic;Djordje Atanackovic;Elke Jäger;Mitsutoshi Matsuo

  • CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma

    Padmanee Sharma;Yu Shen;Sijin Wen;Sachiko Yamada

  • Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers.

    Elke Jäger;Sacha Gnjatic;Yasuhiro Nagata;Elisabeth Stockert

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C)

    Conor N. Gruber;Roosheel S. Patel;Rebecca Trachtman;Lauren Lepow

  • Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses

    E Jäger;Y Nagata;S Gnjatic;H Wada

  • Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4(+) and CD8(+) T cell responses in humans.

    Ian D. Davis;Weisan Chen;Heather Jackson;Phillip Parente;Phillip Parente

Frequent Co-Authors

Lloyd J. Old
Lloyd J. Old Ludwig Cancer Research
Achim A. Jungbluth
Achim A. Jungbluth Memorial Sloan Kettering Cancer Center
Gerd Ritter
Gerd Ritter Memorial Sloan Kettering Cancer Center
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai
Yao-Tseng Chen
Yao-Tseng Chen Cornell University
Nina Bhardwaj
Nina Bhardwaj Icahn School of Medicine at Mount Sinai
Kunle Odunsi
Kunle Odunsi Roswell Park Cancer Institute
Elke Jäger
Elke Jäger Goethe University Frankfurt
Jedd D. Wolchok
Jedd D. Wolchok Cornell University

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