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Best Scientists
2025

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Best Scientists

D-Index
178
Citations
145357
World Ranking
644
National Ranking
403

Immunology

D-Index
180
Citations
147157
World Ranking
36
National Ranking
25

Medicine

D-Index
180
Citations
148070
World Ranking
367
National Ranking
230

Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • 1990 - Robert Koch Prize
  • 1978 - Member of the National Academy of Sciences
  • 1974 - Member of the National Academy of Medicine (NAM)

Overview

Lloyd J. Old was affiliated with Ludwig Cancer Research in the United States. Their research spanned several fields including Biochemistry, Genetics and Molecular Biology, as well as Computer Science. The work covered key subfields such as Molecular Biology, Immunology, Oncology, Computational Theory and Mathematics, and Artificial Intelligence.

The scientist contributed to areas that addressed Immunotherapy and Immune Responses, CAR-T cell therapy research, vaccines and immunoinformatics approaches, Rough Sets and Fuzzy Logic, Biomedical Text Mining and Ontologies, and Semantic Web and Ontologies.

Among the recent publications attributed to Lloyd J. Old were:

  • Results of a randomized, double-blind phase II clinical trial of NY-ESO-1 vaccine with ISCOMATRIX adjuvant versus ISCOMATRIX alone in participants with high-risk resected melanoma, 2020, Journal for ImmunoTherapy of Cancer
  • Modelling Lexical Databases with Formal Concept Analysis, 2020, Research Output (Edinburgh Napier University)

Frequent co-authors included Jonathan Cebon, Martin Gore, John F. Thompson, Ian D. Davis, and Grant A. McArthur.

The main publication venues for their work were the Journal for ImmunoTherapy of Cancer and Research Output (Edinburgh Napier University).

Lloyd J. Old was a recipient of several awards during their career. They were named a Member of the National Academy of Medicine in 1974 and a Member of the National Academy of Sciences in 1978. In 1990, they were awarded the Robert Koch Prize.

Best Publications

  • An endotoxin-induced serum factor that causes necrosis of tumors

    E A Carswell;L J Old;R L Kassel;S Green

  • Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion

    Robert D. Schreiber;Lloyd J. Old;Mark J. Smyth;Mark J. Smyth

  • Cancer immunoediting: from immunosurveillance to tumor escape.

    Gavin P. Dunn;Allen T. Bruce;Hiroaki Ikeda;Lloyd J. Old

  • IFNγ, and lymphocytes prevent primary tumour development and shape tumour immunogenicity

    Vijay Shankaran;Hiroaki Ikeda;Allen T. Bruce;J. Michael White

  • The three Es of cancer immunoediting.

    Gavin P. Dunn;Lloyd J. Old;Robert D. Schreiber

  • The immunobiology of cancer immunosurveillance and immunoediting

    Gavin P. Dunn;Lloyd J. Old;Robert D. Schreiber

  • Tumor necrosis factor (TNF)

    Lloyd J. Old

  • Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

    Eiichi Sato;Sara H. Olson;Jiyoung Ahn;Brian Bundy

  • Antibody therapy of cancer

    Andrew M. Scott;Jedd D. Wolchok;Lloyd J. Old;Lloyd J. Old

  • Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice

    Daniel H. Kaplan;Vijay Shankaran;Anand S. Dighe;Elisabeth Stockert

  • Cancer/testis antigens, gametogenesis and cancer.

    Andrew J. G. Simpson;Otavia L. Caballero;Achim Jungbluth;Yao-Tseng Chen

  • A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening

    Yao-Tseng Chen;Matthew J. Scanlan;Ugur Sahin;Özlem Türeci

  • Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

    Hirokazu Matsushita;Hirokazu Matsushita;Matthew D. Vesely;Daniel C. Koboldt;Charles G. Rickert

  • The roles of IFNγ in protection against tumor development and cancer immunoediting

    Hiroaki Ikeda;Lloyd J Old;Robert D Schreiber

  • Cancer/testis antigens: an expanding family of targets for cancer immunotherapy.

    Matthew J. Scanlan.;Ali O. Gure.;Achim A. Jungbluth.;Lloyd J. Old.

  • The cancer/testis genes: review, standardization, and commentary.

    Matthew J Scanlan;Andrew J G Simpson;Lloyd J Old

  • Tumor-infiltrating NY-ESO-1–specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer

    Junko Matsuzaki;Sacha Gnjatic;Paulette Mhawech-Fauceglia;Amy Beck

  • Characterization of tumor necrosis factor-deficient mice

    Michael W. Marino;Ashley Dunn;Dianne Grail;Melissa Inglese

  • Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers.

    Pilar Garin-Chesa;Lloyd J. Old;Wolfgang J. Rettig

  • A new class of murine leukemia virus associated with development of spontaneous lymphomas

    Janet W. Hartley;Nancy K. Wolford;Lloyd J. Old;Wallace P. Rowe

  • Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse.

    Albert B. Deleo;Gilbert Jay;Ettore Appella;Garrett C. Dubois

Frequent Co-Authors

Yao-Tseng Chen
Yao-Tseng Chen Cornell University
Elisabeth Stockert
Elisabeth Stockert Memorial Sloan Kettering Cancer Center
Achim A. Jungbluth
Achim A. Jungbluth Memorial Sloan Kettering Cancer Center
Gerd Ritter
Gerd Ritter Memorial Sloan Kettering Cancer Center
Herbert F. Oettgen
Herbert F. Oettgen Memorial Sloan Kettering Cancer Center
Sacha Gnjatic
Sacha Gnjatic Icahn School of Medicine at Mount Sinai
Edward A. Boyse
Edward A. Boyse University of Arizona
Andrew M. Scott
Andrew M. Scott La Trobe University
Alexander Knuth
Alexander Knuth University of Zurich
Hiroshi Shiku
Hiroshi Shiku Mie University

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Related Online Degrees & Career Pathways

For those studying Immunology in the USA, exploring related healthcare degrees can open diverse career opportunities. Nursing pathways, for example, often complement immunology knowledge, especially in clinical and research settings.

If you’re considering advancing into nursing, some students look for the easiest ABSN program to get into, which can accelerate the transition from a non-nursing background. Similarly, those seeking foundational nursing credentials may find value in LPN schools easy to get into, allowing for a quicker start in patient care roles that involve immunology-related tasks.

For advanced practice, many immunology graduates pursue nurse practitioner degrees. Finding the what is the easiest NP program can help reduce time and cost barriers while maintaining quality education.

Mental health is also closely linked to immunology through biopsychosocial approaches. Those interested might explore best PMHNP programs online, which offer strong clinical placement rates and flexibility for working professionals.

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