World's Best Scientists 2026 revealed!
Hiroshi Shiku

Hiroshi Shiku

D-Index & Metrics

Immunology

D-Index
85
Citations
24420
World Ranking
1325
National Ranking
52

Medicine

D-Index
86
Citations
25200
World Ranking
14211
National Ranking
434

Hiroshi Shiku publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Hiroshi Shiku sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 586 publications — 93rd percentile

93% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Hiroshi Shiku D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroshi Shiku sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 85 D-Index — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Hiroshi Shiku was affiliated with Mie University in Japan. The research focus spanned several closely related fields, including immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology.

The primary subfields of study related to their work included immunology, oncology, molecular biology, biomedical engineering, and genetics.

Key topics covered in their research included:

  • CAR-T cell therapy research
  • Immunotherapy and immune responses
  • Immune cell function and interaction
  • Viral infectious diseases and gene expression in insects
  • RNA interference and gene delivery
  • T-cell and B-cell immunology
  • Virus-based gene therapy research

Frequent collaborators in their research were:

  • С. В. Сенников
  • Yoshihiro Miyahara
  • Julia Shevchenko
  • Yasushi Akahori
  • Shinichi Kageyama

Academic publications were common in several venues, notably:

  • Immunologiya
  • Hematology Transfusion and Cell Therapy
  • Cancer Immunology Immunotherapy
  • Molecular Therapy
  • Regular and Young Investigator Award Abstracts

Some of the recent papers authored or coauthored by Hiroshi Shiku included:

  • Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion-exchange method, 2022, Journal of Extracellular Vesicles
  • MAGE-A4, NY-ESO-1 and SAGE mRNA expression rates and co-expression relationships in solid tumours, 2020, BMC Cancer
  • NY-ESO-1-specific redirected T cells with endogenous TCR knockdown mediate tumor response and cytokine release syndrome, 2022, Journal for ImmunoTherapy of Cancer
  • Assessment of Surface Glycan Diversity on Extracellular Vesicles by Lectin Microarray and Glycoengineering Strategies for Drug Delivery Applications, 2021, Small Methods
  • A phase 1 trial of NY-ESO-1-specific TCR-engineered T-cell therapy combined with a lymph node-targeting nanoparticulate peptide vaccine for the treatment of advanced soft tissue sarcoma, 2023, International Journal of Cancer

Best Publications

  • Engineering hybrid exosomes by membrane fusion with liposomes.

    Yuko T. Sato;Kaori Umezaki;Shinichi Sawada;Sada Atsu Mukai

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

    K Takamiya;A Yamamoto;K Furukawa;S Yamashiro

  • De novo CD5+ diffuse large B-cell lymphoma: a clinicopathologic study of 109 patients

    Motoko Yamaguchi;Masao Seto;Masataka Okamoto;Ryo Ichinohasama

  • Isolation of GD3 synthase gene by expression cloning of GM3 alpha-2,8-sialyltransferase cDNA using anti-GD2 monoclonal antibody

    M Haraguchi;S Yamashiro;A Yamamoto;K Furukawa

  • Cell surface antigens of chemically induced sarcomas of the mouse. I. Murine leukemia virus-related antigens and alloantigens on cultured fibroblasts and sarcoma cells: description of a unique antigen on BALB/c Meth A sarcoma.

    Albert B. DeLEO;Hiroshi Shiku;Toshitada Takahashi;Mary John

  • Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells.

    H Shiku;P Kisielow;M A Bean;T Takahashi

  • Expression of tissue factor and vascular endothelial growth factor is associated with angiogenesis in colorectal cancer.

    Takahiro Nakasaki;Hideo Wada;Chika Shigemori;Chikao Miki

  • Serological analysis of cell surface antigens of malignant human brain tumors.

    Michael Pfreundschuh;Hiroshi Shiku;Toshitada Takahashi;Ryuzo Ueda

  • Ly antigens as markers for functionally distinct subpopulations of thymus-derived lymphocytes of the mouse.

    P Kisielow;J A Hirst;H Shiku;P C Beverley

  • Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera

    Eiichi Nakayama;Hiroshi Shiku;Elisabeth Stockert;Herbert F. Oettgen

  • RHAMM-R3 peptide vaccination in patients with acute myeloid leukemia, myelodysplastic syndrome, and multiple myeloma elicits immunologic and clinical responses.

    Michael Schmitt;Anita Schmitt;Markus T. Rojewski;Jinfei Chen

  • Improved expression and reactivity of transduced tumor-specific TCRs in human lymphocytes by specific silencing of endogenous TCR.

    Sachiko Okamoto;Junichi Mineno;Hiroaki Ikeda;Hiroshi Fujiwara

  • Notch signalling in hematopoiesis.

    Ohishi K;Katayama N;Shiku H;Varnum-Finney B

  • Outcome of disseminated intravascular coagulation in relation to the score when treatment was begun

    Wada H;Wakita Y;Nakase T;Shimura M

  • CD4+ CD25+ T cells responding to serologically defined autoantigens suppress antitumor immune responses.

    Hiroyoshi Nishikawa;Takuma Kato;Koji Tanida;Atsunori Hiasa

  • In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines.

    Hiroyoshi Nishikawa;Eiichi Sato;Gabriel Briones;Li-Mei Chen

  • Reduced Cd4 + Cd25 + T cells in patients with idiopathic thrombocytopenic purpura

    Miho Sakakura;Hideo Wada;Isao Tawara;Tsutomu Nobori

  • Peptides derived from a wild-type murine proto-oncogene c-erbB-2/HER2/neu can induce CTL and tumor suppression in syngeneic hosts.

    Y Nagata;R Furugen;A Hiasa;H Ikeda

  • Activated CD8 + T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells

    Naohiro Seo;Yoshitaka Shirakura;Yoshiro Tahara;Fumiyasu Momose

  • Cell surface antigens of human malignant melanoma. III. Recognition of autoantibodies with unusual characteristics.

    H Shiku;T Takahashi;L A Resnick;H F Oettgen

Frequent Co-Authors

Hiroyoshi Nishikawa
Hiroyoshi Nishikawa Nagoya University
Lloyd J. Old
Lloyd J. Old Ludwig Cancer Research
Masaki Yasukawa
Masaki Yasukawa Ehime University
Koichi Furukawa
Koichi Furukawa Chubu University
Kazunari Akiyoshi
Kazunari Akiyoshi Kyoto University
Takeshi Urano
Takeshi Urano Shimane University
Herbert F. Oettgen
Herbert F. Oettgen Memorial Sloan Kettering Cancer Center
Sacha Gnjatic
Sacha Gnjatic Icahn School of Medicine at Mount Sinai
Gerd Ritter
Gerd Ritter Memorial Sloan Kettering Cancer Center
Kogo Takamiya
Kogo Takamiya University of Miyazaki

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