D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 57 Citations 9,569 205 World Ranking 1988 National Ranking 68

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

Hiroshi Shiku mainly focuses on Immunology, Antigen, Molecular biology, Cytotoxic T cell and Pathology. His study in Antibody, Immunotherapy, Immune system, T cell and Cancer vaccine are all subfields of Immunology. The various areas that Hiroshi Shiku examines in his Antigen study include Cell culture, Cell and Chronic myelogenous leukemia.

His study in Molecular biology is interdisciplinary in nature, drawing from both Genetics, Gene expression, Gene, Cytotoxicity and CTL*. Hiroshi Shiku interconnects Fibrosarcoma and Cell biology in the investigation of issues within Cytotoxic T cell. His Pathology study combines topics from a wide range of disciplines, such as Cancer, Colorectal cancer, Cancer research and Pancreas.

His most cited work include:

  • Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system (323 citations)
  • Eradication of Established Tumors by CD8+ T Cell Adoptive Immunotherapy (293 citations)
  • De novo CD5+ diffuse large B-cell lymphoma: a clinicopathologic study of 109 patients (257 citations)

What are the main themes of his work throughout his whole career to date?

Hiroshi Shiku mainly investigates Immunology, Molecular biology, Cancer research, Antigen and Internal medicine. His Immunology study typically links adjacent topics like Cell biology. His Molecular biology study deals with Cytotoxic T cell intersecting with CD8 and T cell.

His research in Cancer research intersects with topics in Cell culture, Colorectal cancer and Tumor antigen. His studies deal with areas such as Cancer, Cancer vaccine and Antibody as well as Antigen. His Internal medicine study combines topics in areas such as Gastroenterology, Endocrinology, Oncology and Pathology.

He most often published in these fields:

  • Immunology (33.77%)
  • Molecular biology (27.61%)
  • Cancer research (22.39%)

What were the highlights of his more recent work (between 2011-2021)?

  • Immunology (33.77%)
  • Antigen (22.39%)
  • Cancer research (22.39%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, Antigen, Cancer research, T cell and Cytotoxic T cell. His Antigen research incorporates elements of Cancer, Chimeric antigen receptor and Monoclonal antibody. His biological study spans a wide range of topics, including Cell culture, CD28, Sarcoma, Cell therapy and Tumor antigen.

His work deals with themes such as Cell, Peripheral blood mononuclear cell and CD8, which intersect with T cell. His study in Cytotoxic T cell is interdisciplinary in nature, drawing from both Molecular biology and Cell biology. Hiroshi Shiku works mostly in the field of Immune system, limiting it down to concerns involving Antibody and, occasionally, Adverse effect.

Between 2011 and 2021, his most popular works were:

  • Classification of current anticancer immunotherapies (249 citations)
  • Engineering hybrid exosomes by membrane fusion with liposomes. (180 citations)
  • Adoptive Transfer of MAGE-A4 T-cell Receptor Gene-Transduced Lymphocytes in Patients with Recurrent Esophageal Cancer (91 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

His primary areas of study are Immunology, Antigen, Immune system, Cancer research and Cytotoxic T cell. His Antigen research is multidisciplinary, incorporating perspectives in Cell therapy, Chimeric antigen receptor, Monoclonal antibody and Cancer immunotherapy. His work carried out in the field of Immune system brings together such families of science as Cancer, Tumor progression, Colitis and Cell biology.

His research in Cancer research focuses on subjects like Cell culture, which are connected to Major histocompatibility complex and In vivo. His Cytotoxic T cell study integrates concerns from other disciplines, such as T cell, Stromal cell and Mesenchymal stem cell. His IL-2 receptor study combines topics in areas such as Molecular biology and Antigen-presenting cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

K Takamiya;A Yamamoto;K Furukawa;S Yamashiro.
Proceedings of the National Academy of Sciences of the United States of America (1996)

498 Citations

Eradication of Established Tumors by CD8+ T Cell Adoptive Immunotherapy

Holly L Hanson;David L Donermeyer;Hiroaki Ikeda;J.Michael White.
Immunity (2000)

451 Citations

De novo CD5+ diffuse large B-cell lymphoma: a clinicopathologic study of 109 patients

Motoko Yamaguchi;Masao Seto;Masataka Okamoto;Ryo Ichinohasama.
Blood (2002)

376 Citations

Classification of current anticancer immunotherapies

Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué.
Oncotarget (2014)

340 Citations

Cell surface antigens of human malignant melanoma. II. Serological typing with immune adherence assays and definition of two new surface antigens.

H Shiku;T Takahashi;H F Oettgen.
Journal of Experimental Medicine (1976)

296 Citations

Cell surface antigens of chemically induced sarcomas of the mouse. I. Murine leukemia virus-related antigens and alloantigens on cultured fibroblasts and sarcoma cells: description of a unique antigen on BALB/c Meth A sarcoma.

Albert B. DeLEO;Hiroshi Shiku;Toshitada Takahashi;Mary John.
Journal of Experimental Medicine (1977)

278 Citations

Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells.

H Shiku;P Kisielow;M A Bean;T Takahashi.
Journal of Experimental Medicine (1975)

271 Citations

Serological analysis of cell surface antigens of malignant human brain tumors.

Michael Pfreundschuh;Hiroshi Shiku;Toshitada Takahashi;Ryuzo Ueda.
Proceedings of the National Academy of Sciences of the United States of America (1978)

269 Citations

Isolation of GD3 synthase gene by expression cloning of GM3 alpha-2,8-sialyltransferase cDNA using anti-GD2 monoclonal antibody

M Haraguchi;S Yamashiro;A Yamamoto;K Furukawa.
Proceedings of the National Academy of Sciences of the United States of America (1994)

263 Citations

Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera

Eiichi Nakayama;Hiroshi Shiku;Elisabeth Stockert;Herbert F. Oettgen.
Proceedings of the National Academy of Sciences of the United States of America (1979)

256 Citations

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