What is he best known for?
The fields of study he is best known for:
- Immune system
- Gene
- Cancer
Immunology, IL-2 receptor, FOXP3, Immune system and Cytotoxic T cell are his primary areas of study.
His is doing research in Antigen, Autoimmunity, T cell, Immunotherapy and Self Tolerance, both of which are found in Immunology.
His IL-2 receptor research incorporates themes from Interleukin 21, CD8 and Autoimmune disease.
His biological study spans a wide range of topics, including Immune homeostasis, CTLA-4, Epigenetics and Cell biology.
The concepts of his Immune system study are interwoven with issues in Monoclonal antibody, Function and In vivo.
His work in Cytotoxic T cell covers topics such as Molecular biology which are related to areas like Streptamer, CD1 and microRNA.
His most cited work include:
- Control of Regulatory T Cell Development by the Transcription Factor Foxp3 (6828 citations)
- Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. (5288 citations)
- Regulatory T Cells and Immune Tolerance (3409 citations)
What are the main themes of his work throughout his whole career to date?
Shimon Sakaguchi mainly focuses on Immunology, FOXP3, IL-2 receptor, Immune system and Cell biology.
His Immunology and T cell, Antigen, Autoimmunity, Autoimmune disease and Regulatory T cell investigations all form part of his Immunology research activities.
The various areas that Shimon Sakaguchi examines in his FOXP3 study include Cancer research, Transcription factor, Immune tolerance, CTLA-4 and Epigenetics.
Shimon Sakaguchi interconnects Natural killer T cell, Interleukin 21 and Antigen-presenting cell in the investigation of issues within IL-2 receptor.
He has included themes like Monoclonal antibody and Effector in his Immune system study.
His studies deal with areas such as Receptor, Cell and CD40 as well as Cell biology.
He most often published in these fields:
- Immunology (84.31%)
- FOXP3 (57.30%)
- IL-2 receptor (42.05%)
What were the highlights of his more recent work (between 2015-2021)?
- FOXP3 (57.30%)
- Immunology (84.31%)
- Immune system (39.65%)
In recent papers he was focusing on the following fields of study:
FOXP3, Immunology, Immune system, Cell biology and IL-2 receptor are his primary areas of study.
His FOXP3 study combines topics in areas such as Cancer research, Epigenetics, Transcription factor, Gene and Effector.
His Immunology study frequently involves adjacent topics like Cell.
His work deals with themes such as Disease and Antigen, which intersect with Immune system.
His Cell biology research incorporates themes from CD28, Germinal center, Immune tolerance and T-cell receptor.
His studies link CD40 with IL-2 receptor.
Between 2015 and 2021, his most popular works were:
- Regulatory T cells in cancer immunotherapy (499 citations)
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (345 citations)
- Two FOXP3 + CD4 + T cell subpopulations distinctly control the prognosis of colorectal cancers (332 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Cancer
Shimon Sakaguchi mostly deals with FOXP3, Immunology, Immune system, Autoimmunity and Cell biology.
His FOXP3 study combines topics from a wide range of disciplines, such as Cancer research, T cell, CTLA-4, Transcription factor and Effector.
His study in Immunology concentrates on Regulatory T cell, IL-2 receptor, Arthritis, Immune tolerance and Autoimmune disease.
In his work, Cytometry, Immunophenotyping, Immunologic Technique, Mass cytometry and Flow cytometry is strongly intertwined with Monoclonal antibody, which is a subfield of Immune system.
His Autoimmunity study integrates concerns from other disciplines, such as Inflammation and Cancer.
His work on Homeostasis as part of general Cell biology research is often related to Branched-chain amino acid, thus linking different fields of science.
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