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Shimon Sakaguchi

Shimon Sakaguchi

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Immunology
Japan
2026
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Medicine
Japan
2023

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Immunology 136 180 167 10 10 482 137253
Medicine 136 1927 1797 36 35 485 137258

Shimon Sakaguchi publications per year

The chart shows the history of publications by Shimon Sakaguchi between 1981 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Shimon Sakaguchi published across 45 years, from 1981 to 2025, averaging 14.3 papers a year. Output peaked at 107 publications in 2023. 63 of the 642 publications appeared in the last two years.

No. of publications
25 50 75 100
Bar chart. Horizontal axis: year, 1981 to 2025. Vertical axis: number of publications, 0 to 107. Peak 107 publications in 2023. 1981: 1 publication 1982: 3 publications 1983: 1 publication 1984: 0 publications 1985: 3 publications 1986: 0 publications 1987: 0 publications 1988: 2 publications 1989: 1 publication 1990: 1 publication 1991: 0 publications 1992: 1 publication 1993: 0 publications 1994: 4 publications 1995: 0 publications 1996: 2 publications 1997: 1 publication 1998: 1 publication 1999: 5 publications 2000: 9 publications 2001: 4 publications 2002: 5 publications 2003: 15 publications 2004: 27 publications 2005: 28 publications 2006: 34 publications 2007: 18 publications 2008: 14 publications 2009: 22 publications 2010: 31 publications 2011: 23 publications 2012: 24 publications 2013: 18 publications 2014: 23 publications 2015: 12 publications 2016: 26 publications 2017: 23 publications 2018: 12 publications 2019: 28 publications 2020: 19 publications 2021: 19 publications 2022: 12 publications 2023: 107 publications 2024: 24 publications 2025: 39 publications
1981 2025

642 publications in total across all disciplines

View publications per year as a table
Shimon Sakaguchi: publications per year, 1981 to 2025
Year Publications
1981 1
1982 3
1983 1
1984 0
1985 3
1986 0
1987 0
1988 2
1989 1
1990 1
1991 0
1992 1
1993 0
1994 4
1995 0
1996 2
1997 1
1998 1
1999 5
2000 9
2001 4
2002 5
2003 15
2004 27
2005 28
2006 34
2007 18
2008 14
2009 22
2010 31
2011 23
2012 24
2013 18
2014 23
2015 12
2016 26
2017 23
2018 12
2019 28
2020 19
2021 19
2022 12
2023 107
2024 24
2025 39
Total 642
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Shimon Sakaguchi publications per year - data summary

  • Shimon Sakaguchi, a Immunology scholar from Osaka University, has 642 publications recorded across 45 years, from 1981 to 2025.
  • The oldest publication on record dates to 1981 and the most recent to 2025.
  • The most productive year is 2023, with 107 publications.
  • The least productive years with any output are 1981, 1983, 1989, 1990 and others, with 1 publication each.
  • 6 of the 45 years in the span carry no publications at all (1984, 1986, 1987, 1991 and others).
  • The rate of publication averages 14.3 papers per year over the whole span, or 16.5 per year counting only the 39 years with at least one publication.
  • The last 5 years on the chart (2021-2025) hold 201 publications, 31% of the career total.
  • Split into equal eras - 1981-1995: 17 publications (1.1 per year); 1996-2010: 216 publications (14.4 per year); 2011-2025: 409 publications (27.3 per year).
  • Comparing the opening and closing eras, the overall trend of publication is rising.

Shimon Sakaguchi publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Shimon Sakaguchi sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 76 bars. Horizontal axis: publications, 62–71 to 807+. Vertical axis: number of scientists, 0 to 189. Most scientists, 189, have 152–161 publications. The last bar groups every scientist with 807 publications or more. The highlighted bar, 482–491 publications, is where this scientist sits. 62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientist 807+ publications: 100 scientists
62–71 publications 807+

This scientist: 482 publications — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

View publications distribution as a table
Number of Immunology scientists by publication count, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
Publications Scientists This scientist
62–71 9
72–81 23
82–91 40
92–101 72
102–111 86
112–121 108
122–131 150
132–141 160
142–151 159
152–161 189
162–171 166
172–181 181
182–191 188
192–201 187
202–211 178
212–221 158
222–231 168
232–241 159
242–251 160
252–261 148
262–271 116
272–281 125
282–291 115
292–301 111
302–311 95
312–321 97
322–331 97
332–341 99
342–351 96
352–361 69
362–371 76
372–381 71
382–391 71
392–401 62
402–411 54
412–421 41
422–431 63
432–441 53
442–451 31
452–461 42
462–471 40
472–481 29
482–491 34 482
492–501 30
502–511 23
512–521 41
522–531 29
532–541 28
542–551 16
552–561 18
562–571 18
572–581 17
582–591 17
592–601 17
602–611 19
612–621 13
622–631 12
632–641 11
642–651 16
652–661 9
662–671 5
672–681 13
682–691 12
692–701 6
702–711 6
712–721 9
722–731 9
732–741 6
742–751 11
752–761 10
762–771 7
772–781 12
782–791 7
792–801 5
802–806 1
807+ 100
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Shimon Sakaguchi publication distribution in Immunology in 2026 - data summary

  • The chart plots the publication count of all 4,929 Immunology scientists ranked by Research.com in 2026, grouped into 76 ranges running from 62–71 to 807+ publications.
  • Shimon Sakaguchi, a Immunology scholar from Osaka University, records 482 publications - the 88th percentile of the discipline.
  • 88% of ranked Immunology scientists score the same or lower than Shimon Sakaguchi, and about 12% score higher.
  • The median of the discipline falls in the 242–251 publications range, and Shimon Sakaguchi ranks above the median.
  • The most crowded range is 152–161 publications, holding 189 scientists (4% of the field).
  • 52% of the field sits in the lowest quarter of the value range (up to 242–251 publications), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 807 publications or more, 100 scientists in all (2% of the field).

Shimon Sakaguchi D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Shimon Sakaguchi sits on this spectrum.

No. of scientists
50 100 150 200
Bar chart with 60 bars. Horizontal axis: D-Index, 40–41 to 157+. Vertical axis: number of scientists, 0 to 201. Most scientists, 201, have 58–59 D-Index. The last bar groups every scientist with 157 D-Index or more. The highlighted bar, 136–137 D-Index, is where this scientist sits. 40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40–41 D-Index 157+

This scientist: 136 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

View D-Index distribution as a table
Number of Immunology scientists by D-index, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
D-Index Scientists This scientist
40–41 28
42–43 91
44–45 157
46–47 192
48–49 175
50–51 188
52–53 177
54–55 155
56–57 194
58–59 201
60–61 197
62–63 201
64–65 173
66–67 167
68–69 172
70–71 199
72–73 184
74–75 133
76–77 163
78–79 127
80–81 121
82–83 125
84–85 121
86–87 102
88–89 96
90–91 75
92–93 72
94–95 74
96–97 66
98–99 68
100–101 49
102–103 60
104–105 54
106–107 36
108–109 23
110–111 52
112–113 41
114–115 34
116–117 25
118–119 28
120–121 11
122–123 20
124–125 27
126–127 19
128–129 20
130–131 16
132–133 17
134–135 14
136–137 15 136
138–139 9
140–141 11
142–143 9
144–145 9
146–147 7
148–149 7
150–151 7
152–153 5
154–155 8
156 6
157+ 96
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Shimon Sakaguchi D-index placement in Immunology in 2026 - data summary

  • The chart plots the discipline H-index (D-index) of all 4,929 Immunology scientists ranked by Research.com in 2026, grouped into 60 ranges running from 40–41 to 157+ D-Index.
  • Shimon Sakaguchi, a Immunology scholar from Osaka University, records 136 D-Index - the 96th percentile of the discipline.
  • 96% of ranked Immunology scientists score the same or lower than Shimon Sakaguchi, and about 4% score higher.
  • The median of the discipline falls in the 68–69 D-Index range, and Shimon Sakaguchi ranks above the median.
  • The most crowded range is 58–59 D-Index, holding 201 scientists (4% of the field).
  • 50% of the field sits in the lowest quarter of the value range (up to 68–69 D-Index), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 157 D-Index or more, 96 scientists in all (2% of the field).

Research.com Recognitions

  • 2026 - Research.com Immunology in Japan Leader Award
  • 2025 - Research.com Immunology in Japan Leader Award
  • 2023 - Research.com Immunology in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award
  • 2022 - Research.com Immunology in Japan Leader Award
  • 2020 - Paul Ehrlich and Ludwig Darmstaedter Prize
  • 2020 - Robert Koch Prize
  • 2015 - Canada Gairdner International Award
  • 2012 - Member of the National Academy of Sciences
  • 2008 - Keio Medical Science Prize, Keio University, Tokyo, Japan

Overview

Shimon Sakaguchi is affiliated with Osaka University in Japan and has an extensive research portfolio primarily in the field of Immunology and Microbiology, with 180 publications. Their work spans subfields including Immunology, Molecular Biology, Oncology, Genetics, and Infectious Diseases.

The scientist's research topics focus on immune cell function and interaction, T-cell and B-cell immunology, immunotherapy and immune responses, single-cell and spatial transcriptomics, cancer immunotherapy and biomarkers, diabetes and associated disorders, and CAR-T cell therapy research.

Major publication venues for Shimon Sakaguchi include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • The Journal of Experimental Medicine
  • Immunity
  • European Journal of Immunology

Notable recent papers by or involving this scientist include:

  • Regulatory T Cells and Human Disease, 2020, Annual Review of Immunology
  • Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells, 2021, Nature Biotechnology
  • Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy, 2023, Cancer Cell
  • Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells, 2021, Proceedings of the National Academy of Sciences
  • Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases, 2020, Cell Research

Frequent co-authors collaborating with Sakaguchi include:

  • Naganari Ohkura
  • James B. Wing
  • Norihisa Mikami
  • Yamami Nakamura
  • Ryoji Kawakami

Shimon Sakaguchi has been recognized with a number of awards, reflecting their contributions across the immunology landscape. Awards include:

  • Paul Ehrlich and Ludwig Darmstaedter Prize, 2020
  • Robert Koch Prize, 2020
  • Canada Gairdner International Award, 2015
  • Member of the National Academy of Sciences, 2012
  • Keio Medical Science Prize, Keio University, Tokyo, Japan, 2008

Best Publications

  • Control of Regulatory T Cell Development by the Transcription Factor Foxp3

    Shohei Hori;Takashi Nomura;Shimon Sakaguchi

  • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.

    Shimon Sakaguchi;Noriko Sakaguchi;Masanao Asano;Misako Itoh

  • Regulatory T Cells and Immune Tolerance

    Shimon Sakaguchi;Shimon Sakaguchi;Tomoyuki Yamaguchi;Takashi Nomura;Masahiro Ono

  • Naturally Arising CD4+ Regulatory T Cells for Immunologic Self-Tolerance and Negative Control of Immune Responses

    Shimon Sakaguchi

  • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self.

    Shimon Sakaguchi

  • CTLA-4 Control over Foxp3+ Regulatory T Cell Function

    Kajsa Wing;Yasushi Onishi;Yasushi Onishi;Paz Prieto-Martin;Tomoyuki Yamaguchi

  • Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

    Koji Atarashi;Takeshi Tanoue;Kenshiro Oshima;Wataru Suda

  • FOXP3 + regulatory T cells in the human immune system

    Shimon Sakaguchi;Makoto Miyara;Makoto Miyara;Cristina M. Costantino;Cristina M. Costantino;David A. Hafler;David A. Hafler

  • Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4

    Takeshi Takahashi;Tomoyuki Tagami;Sayuri Yamazaki;Toshimitsu Uede

  • Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

    Makoto Miyara;Yumiko Yoshioka;Akihiko Kitoh;Tomoko Shima

  • Stimulation of CD25 + CD4 + regulatory T cells through GITR breaks immunological self-tolerance

    Jun Shimizu;Sayuri Yamazaki;Takeshi Takahashi;Yasumasa Ishida

  • Regulatory T cells: key controllers of immunologic self-tolerance.

    Shimon Sakaguchi

  • Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance.

    Shimon Sakaguchi;Noriko Sakaguchi;Jun Shimizu;Sayuri Yamazaki

  • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.

    Takeshi Takahashi;Yuhshi Kuniyasu;Masaaki Toda;Noriko Sakaguchi

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

    Shimon Sakaguchi;Masahiro Ono;Ruka Setoguchi;Haruhiko Yagi

  • Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity.

    Jun Shimizu;Sayuri Yamazaki;Shimon Sakaguchi

  • Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation.

    Masanao Asano;Masaaki Toda;Noriko Sakaguchi;Shimon Sakaguchi

  • Regulatory T cells in cancer immunotherapy

    Atsushi Tanaka;Shimon Sakaguchi

  • Regulatory T cells in transplantation tolerance.

    Kathryn J. Wood;Shimon Sakaguchi

  • Regulatory T cells: Meden Agan

    Shimon Sakaguchi

Frequent Co-Authors

Hiroyoshi Nishikawa
Hiroyoshi Nishikawa Nagoya University
Takashi Nomura
Takashi Nomura Kyoto University
Kathryn J. Wood
Kathryn J. Wood University of Oxford
Shohei Hori
Shohei Hori University of Tokyo
Shinji Uemoto
Shinji Uemoto Kyoto University
Nagahiro Minato
Nagahiro Minato Kyoto University
Yoshiki Miyachi
Yoshiki Miyachi Kyoto University
Kiyoshi Takeda
Kiyoshi Takeda Osaka University
Atsushi Kumanogoh
Atsushi Kumanogoh Osaka University
Alan N. Houghton
Alan N. Houghton Memorial Sloan Kettering Cancer Center

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