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Biology and Biochemistry

D-Index
50
Citations
37320
World Ranking
17381
National Ranking
1254

Overview

Shohei Hori is affiliated with the University of Tokyo in Japan. Their research primarily focuses on immunology, with a substantial body of work related to immune cell function, T-cell and B-cell immunology, and immunotherapy. Their contributions also extend into related fields such as oncology, obstetrics and gynecology, molecular biology, and genetics.

Their research covers a range of topics including:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • IL-33, ST2, and ILC Pathways
  • Reproductive System and Pregnancy
  • Pregnancy and preeclampsia studies
  • Cancer Immunotherapy and Biomarkers

They have authored multiple papers, with notable recent publications including:

  • FOXP3 as a master regulator of Treg cells, 2021, Nature Reviews. Immunology
  • Peripheral tolerance by Treg via constraining OX40 signal in autoreactive T cells against desmoglein 3, a target antigen in pemphigus, 2021, Proceedings of the National Academy of Sciences
  • Diet-mediated constitutive induction of novel IL-4+ ILC2 cells maintains intestinal homeostasis in mice, 2023, The Journal of Experimental Medicine
  • Cathepsin W restrains peripheral regulatory T cells for mucosal immune quiescence, 2023, Science Advances
  • Whole embryonic detection of maternal microchimeric cells highlights significant differences in their numbers among individuals, 2021, PLoS ONE

Frequent coauthors in their research include:

  • Akira Nakajima
  • Ryuichi Murakami
  • Masato Kubo
  • Kenya Honda
  • Kana Fujimoto

Publications by Shohei Hori have appeared in established venues such as:

  • Scientific Reports
  • The Journal of Immunology
  • Nature Reviews. Immunology
  • The Journal of Experimental Medicine
  • Proceedings of the National Academy of Sciences

Their main fields of study include:

  • Immunology and Microbiology
  • Medicine

Within these domains, Hori's research has contributed to expanding knowledge on regulatory T cells, immune tolerance mechanisms, and mucosal immune homeostasis among others.

Best Publications

  • Control of Regulatory T Cell Development by the Transcription Factor Foxp3

    Shohei Hori;Takashi Nomura;Shimon Sakaguchi

  • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

    Yukihiro Furusawa;Yuuki Obata;Shinji Fukuda;Takaho A. Endo

  • Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

    Koji Atarashi;Takeshi Tanoue;Tatsuichiro Shima;Akemi Imaoka

  • Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

    Shimon Sakaguchi;Masahiro Ono;Ruka Setoguchi;Haruhiko Yagi

  • Homeostatic maintenance of natural Foxp3+ CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

    Ruka Setoguchi;Shohei Hori;Takeshi Takahashi;Shimon Sakaguchi

  • Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

    Haruhiko Yagi;Takashi Nomura;Kyoko Nakamura;Sayuri Yamazaki

  • Regulatory T cells: recommendations to simplify the nomenclature

    Abul K Abbas;Christophe Benoist;Jeffrey A Bluestone;Daniel J Campbell

  • Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches

    Masayuki Tsuji;Noriko Komatsu;Shimpei Kawamoto;Keiichiro Suzuki

  • Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

    Takahisa Miyao;Stefan Floess;Ruka Setoguchi;Hervé Luche

  • Heterogeneity of natural Foxp3+ T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

    Noriko Komatsu;Maria Encarnita Mariotti-Ferrandiz;Ying Wang;Bernard Malissen

  • Foxp3 Inhibits RORγt-mediated IL-17A mRNA Transcription through Direct Interaction with RORγt

    Kenji Ichiyama;Hideyuki Yoshida;Yu Wakabayashi;Takatoshi Chinen

  • Foxp3: a critical regulator of the development and function of regulatory T cells.

    Shohei Hori;Shimon Sakaguchi

  • Control of autoimmunity by naturally arising regulatory CD4+ T cells.

    Shohei Hori;Takeshi Takahashi;Shimon Sakaguchi

  • IL-17-producing γδ T cells enhance bone regeneration

    Takehito Ono;Kazuo Okamoto;Tomoki Nakashima;Takeshi Nitta

  • CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice.

    Shohei Hori;Thiago L Carvalho;Jocelyne Demengeot

  • Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice

    Michio Tomura;Tetsuya Honda;Hideaki Tanizaki;Atsushi Otsuka

  • Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice

    Shohei Hori;Matthias Haury;António Coutinho;Jocelyne Demengeot

  • Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus

    Aras Toker;Dirk Engelbert;Garima Garg;Julia K. Polansky

  • The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells.

    Takashi Sekiya;Ikkou Kashiwagi;Naoko Inoue;Rimpei Morita

  • The Transcription Factor E4BP4 Regulates the Production of IL-10 and IL-13 in CD4+ T Cells

    Yasutaka Motomura;Hiroshi Kitamura;Atsushi Hijikata;Yuko Matsunaga

Frequent Co-Authors

Shimon Sakaguchi
Shimon Sakaguchi Osaka University
Herman Waldmann
Herman Waldmann University of Oxford
Kenya Honda
Kenya Honda Keio University
Jocelyne Demengeot
Jocelyne Demengeot Instituto Gulbenkian de Ciência
Osamu Ohara
Osamu Ohara Chiba University
Akihiko Yoshimura
Akihiko Yoshimura Keio University
Koji Hase
Koji Hase Keio University
Haruhiko Koseki
Haruhiko Koseki RIKEN Center for Integrative Medical Sciences

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