2023 - Research.com Immunology in Germany Leader Award
The scientist’s investigation covers issues in Immunology, FOXP3, Immune system, Cell biology and Cytotoxic T cell. His study brings together the fields of Cancer research and Immunology. His research integrates issues of Regulatory T cell, IL-2 receptor, Immune tolerance, Receptor and Adoptive cell transfer in his study of FOXP3.
His work investigates the relationship between Immune system and topics such as Antibody that intersect with problems in Cell culture and Melanoma. His Cell biology study integrates concerns from other disciplines, such as Biochemistry, Cellular differentiation, CpG site and Transcription factor. His biological study spans a wide range of topics, including Molecular biology, CpG Oligodeoxynucleotide, CD8 and T helper cell.
His primary scientific interests are in Immunology, FOXP3, Immune system, Cell biology and T cell. His work focuses on many connections between Immunology and other disciplines, such as Cytotoxic T cell, that overlap with his field of interest in Virology. His FOXP3 study deals with Regulatory T cell intersecting with Immunotherapy.
His Immune system study frequently draws parallels with other fields, such as Cytokine. While the research belongs to areas of Cell biology, he spends his time largely on the problem of In vitro, intersecting his research to questions surrounding In vivo. Tim Sparwasser interconnects Natural killer T cell, Molecular biology, Interleukin 21 and Cellular differentiation in the investigation of issues within IL-2 receptor.
His main research concerns Cell biology, Immunology, Immune system, Inflammation and Effector. His Cell biology research incorporates elements of Dendritic cell, In vitro, Cytokine and FOXP3. Tim Sparwasser studies Colitis which is a part of Immunology.
His Immune system research integrates issues from Immunopathology and TSPAN2. His work carried out in the field of Inflammation brings together such families of science as Acquired immune system, Spleen, Monocyte, Regulatory T cell and Cell fate determination. His Effector study incorporates themes from Lipogenesis and Cancer research.
His scientific interests lie mostly in Cell biology, Immune system, FOXP3, Cytokine and Inflammation. His study in the field of Intracellular parasite is also linked to topics like Leishmania donovani. His work deals with themes such as Colitis and Weaning, which intersect with Immune system.
His study in FOXP3 is interdisciplinary in nature, drawing from both Dendritic cell and Polyamine. His Cytokine study combines topics in areas such as Experimental autoimmune encephalomyelitis, T cell, Autoimmune disease and Mitochondrion. Antigen is a subfield of Immunology that Tim Sparwasser tackles.
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Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease.
Katharina Lahl;Christoph Loddenkemper;Cathy Drouin;Jennifer Freyer.
Journal of Experimental Medicine (2007)
Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
Tim Sparwasser;Eva Sophie Koch;Ramunas M. Vabulas;Klaus Heeg.
European Journal of Immunology (1998)
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
Olaf Gross;Andreas Gewies;Katrin Finger;Martin Schäfer.
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation.
Hans Häcker;Harald Mischak;Thomas Miethke;Susanne Liptay.
The EMBO Journal (1998)
Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria
Usriansyah Hadis;Benjamin Wahl;Olga Schulz;Matthias Hardtke-Wolenski.
T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
Naganari Ohkura;Naganari Ohkura;Masahide Hamaguchi;Masahide Hamaguchi;Hiromasa Morikawa;Hiromasa Morikawa;Kyoko Sugimura.
De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
Luciana Berod;Christin Friedrich;Amrita Nandan;Jenny Freitag.
Nature Medicine (2014)
Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock.
Tim Sparwasser;Thomas Miethke;Grayson Lipford;Andreas Erdmann.
European Journal of Immunology (1997)
Bacterial DNA causes septic shock
Tim Sparwasser;Thomas Miethke;Grayson Lipford;Katrin Borschert.
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation
Christoph Wilhelm;Keiji Hirota;Benjamin Stieglitz;Jacques Van Snick.
Nature Immunology (2011)
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