D-Index & Metrics Best Publications
Microbiology
Germany
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 68 Citations 16,496 170 World Ranking 1340 National Ranking 90

Research.com Recognitions

Awards & Achievements

2023 - Research.com Microbiology in Germany Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • DNA

His scientific interests lie mostly in Immune system, Immunology, Cytotoxic T cell, Molecular biology and Cell biology. The Immune system study combines topics in areas such as In vitro, Sepsis, Antigen, Vaccination and In vivo. His study on CTL*, Superantigen and Allergy is often connected to Leishmania major as part of broader study in Immunology.

His Cytotoxic T cell research is multidisciplinary, relying on both T cell and Adjuvant. His Molecular biology research includes elements of Oligonucleotide, Major histocompatibility complex and CD40. His Cell biology study combines topics from a wide range of disciplines, such as Membrane potential, Innate immune system and Cytokine.

His most cited work include:

  • Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells (783 citations)
  • CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. (625 citations)
  • T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: critical role of tumor necrosis factor. (537 citations)

What are the main themes of his work throughout his whole career to date?

Klaus Heeg spends much of his time researching Immunology, Immune system, Cell biology, Molecular biology and T cell. Klaus Heeg has included themes like Cytokine, Antigen and Microbiology in his Immune system study. His Cell biology research includes themes of Receptor and Toll-like receptor.

His research in Molecular biology focuses on subjects like In vitro, which are connected to Apoptosis. His T cell research focuses on Cytotoxic T cell and how it connects with CD8. His work on Pattern recognition receptor as part of general Innate immune system study is frequently linked to CpG site, bridging the gap between disciplines.

He most often published in these fields:

  • Immunology (32.62%)
  • Immune system (27.27%)
  • Cell biology (24.60%)

What were the highlights of his more recent work (between 2011-2021)?

  • Immune system (27.27%)
  • Outbreak (6.42%)
  • Internal medicine (7.49%)

In recent papers he was focusing on the following fields of study:

Klaus Heeg mainly investigates Immune system, Outbreak, Internal medicine, Cell biology and Microbiology. His Immune system study is concerned with the larger field of Immunology. Klaus Heeg interconnects Enterococcus faecium, Epidemiology, Infection control, Transmission and Viral shedding in the investigation of issues within Outbreak.

His Cell biology study combines topics in areas such as Secretion, Receptor, Toll-like receptor and Cytokine. His research investigates the link between Toll-like receptor and topics such as Molecular biology that cross with problems in Interleukin 10. Klaus Heeg combines subjects such as Klebsiella pneumoniae, Protein A and Staphylococcus aureus with his study of Microbiology.

Between 2011 and 2021, his most popular works were:

  • Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen (51 citations)
  • Risk factors and containment of respiratory syncytial virus outbreak in a hematology and transplant unit (50 citations)
  • Pathogen-Triggered Activation of Plasmacytoid Dendritic Cells Induces IL-10–Producing B Cells in Response to Staphylococcus aureus (43 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • DNA

Klaus Heeg focuses on Cell biology, Immune system, Microbiology, Secretion and Staphylococcus aureus. His Cell biology study integrates concerns from other disciplines, such as Inflammasome and Cytokine. His Cytokine research incorporates themes from Transcription factor and Autocrine signalling.

His study in Immune system is interdisciplinary in nature, drawing from both Inflammation, Receptor, Epitope, Antibody and Klebsiella pneumoniae. His study in the field of Antibiotic resistance is also linked to topics like Isotype. His Secretion research is multidisciplinary, incorporating perspectives in Molecular biology and Syk.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells

Tim Sparwasser;Eva Sophie Koch;Ramunas M. Vabulas;Klaus Heeg.
European Journal of Immunology (1998)

1017 Citations

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation.

Hans Häcker;Harald Mischak;Thomas Miethke;Susanne Liptay.
The EMBO Journal (1998)

868 Citations

CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis.

Stefan Zimmermann;Oliver Egeter;Susanne Hausmann;Grayson B. Lipford.
Journal of Immunology (1998)

727 Citations

T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: critical role of tumor necrosis factor.

Thomas Miethke;Claudia Wahl;Klaus Heeg;Bernd Echtenacher.
Journal of Experimental Medicine (1992)

716 Citations

Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock.

Tim Sparwasser;Thomas Miethke;Grayson Lipford;Andreas Erdmann.
European Journal of Immunology (1997)

545 Citations

CpG‐containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: A new class of vaccine adjuvants

Grayson B. Lipford;Marc Bauer;Christian Blank;Rudi Reiter.
European Journal of Immunology (1997)

519 Citations

Bacterial DNA causes septic shock

Tim Sparwasser;Thomas Miethke;Grayson Lipford;Katrin Borschert.
Nature (1997)

509 Citations

Distinct mechanisms of immunosuppression as a consequence of major surgery.

T Hensler;H Hecker;K Heeg;C D Heidecke.
Infection and Immunity (1997)

433 Citations

IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice.

Tilo Biedermann;Stephan Zimmermann;Stephan Zimmermann;Hayo Himmelrich;Alain Gumy.
Nature Immunology (2001)

389 Citations

Immunostimulatory DNA: Sequence‐dependent production of potentially harmful or useful cytokines

Grayson B. Lipford;Tim Sparwasser;Marc Bauer;Stefan Zimmermann.
European Journal of Immunology (1997)

352 Citations

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