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Biology and Biochemistry

D-Index
92
Citations
29489
World Ranking
2216
National Ranking
1196

Overview

Sudhir Agrawal is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans multiple disciplines, primarily focusing on Biochemistry, Genetics, and Molecular Biology with significant contributions in Medicine and Computer Science.

The main research subfields include Molecular Biology, Artificial Intelligence, Genetics, Oncology, and Immunology. Within these fields, the scientist has worked on diverse topics such as:

  • RNA Interference and Gene Delivery
  • Cancer Immunotherapy and Biomarkers
  • DNA and Nucleic Acid Chemistry
  • Advanced biosensing and bioanalysis techniques
  • Neurogenetic and Muscular Disorders Research
  • Natural Language Processing Techniques
  • Topic Modeling

Agrawal's recent publications demonstrate a varied scope of interest. Notable papers include:

  • "Tilsotolimod with Ipilimumab Drives Tumor Responses in Anti-PD-1 Refractory Melanoma," 2021, published in Cancer Discovery
  • "The Evolution of Antisense Oligonucleotide Chemistry-A Personal Journey," 2021, published in Biomedicines
  • "RNA Therapeutics Are Stepping Out of the Maze," 2020, published in Trends in Molecular Medicine
  • "Introduction and History of the Chemistry of Nucleic Acids Therapeutics," 2022, published in Methods in molecular biology
  • "Developing antisense oligonucleotides for a TECPR2 mutation-induced, ultra-rare neurological disorder using patient-derived cellular models," 2022, published in Molecular Therapy - Nucleic Acids

The scientist frequently publishes in venues such as arXiv (Cornell University), Cancer Discovery, Methods in molecular biology, Biomedicines, and Trends in Molecular Medicine.

Collaboration is an important aspect of their work, with frequent co-authors including Mingu Lee, Raghavv Goel, Cara Haymaker, Daniel H. Johnson, and Ravi Murthy.

Best Publications

  • Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling

    Sudhir Agrawal;Jinyan Tang

  • Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer

    Richard A. Cardullo;Sudhir Agrawal;Carlos Flores;Paul C. Zamecnik

  • Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

    Sudhir Agrawal;Jamal Temsamani;Jin Yang Tang

  • Antisense oligonucleotides: towards clinical trials

    Sudhir Agrawal

  • Incorporation of multiple reporter groups on synthetic oligonucleotides

    Sudhir Agrawal;Jinyan Tang

  • OLIGONUCLEOTIDOS HIBRIDOS E QUIMERICOS INVERTIDOS

    Agrawal Sudhir

  • Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus

    Sudhir Agrawal;John Goodchild;Maria P. Civeira;Arthur H. Thornton

  • Hybrid oligonucleotide phosphorothioates

    Valeri Metelev;Sudhir Agrawal

  • Method of site-specific alteration of RNA and production of encoded polypeptides

    Thoru Pederson;Sudhir Agrawal;Sandra Mayrand;Paul C. Zamecnik

  • Repair of thalassemic human β-globin mRNA in mammalian cells by antisense oligonucleotides

    Halina Sierakowska;Maria J. Sambade;Sudhir Agrawal;Ryszard Kole

  • Antisense therapeutics: is it as simple as complementary base recognition?

    Sudhir Agrawal;Ekambar R Kandimalla

  • Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates.

    Prem S. Sarin;Sudhir Agrawal;Maria P. Civeira;John Goodchild

  • Method of down-regulating gene expression

    Sudhir Agrawal;Robert B. Diasio;Ruiwen Zhang

  • Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies

    Sudhir Agrawal;Zhiwei Jiang;Qiuyan Zhao;Denise Shaw

  • Specific removal of the nonsense mutation from the mdx dystrophin mRNA using antisense oligonucleotides

    Stephen D Wilton;Frances Lloyd;Kylie Carville;Sue Fletcher

  • Effect of different chemically modified oligodeoxynucleotides on immune stimulation

    Qiuyan Zhao;Jamal Temsamani;Patricia L. Iadarola;Zhiwei Jiang

  • Pharmacokinetics of Antisense Oligonucleotides

    Sudhir Agrawal;Jamal Temsamani;Wayne Galbraith;Jinyan Tang

  • Complement activation and hemodynamic changes following intravenous administration of phosphorothioate oligonucleotides in the monkey.

    Wayne M. Galbraith;William C. Hobson;Patricia C. Giclas;Paul J. Schechter

  • Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides.

    John Goodchild;Sudhir Agrawal;Maria P. Civeira;Prem S. Sarin

  • Efficient methods for attaching non-radioactive labels to the 5' ends of synthetic oligodeoxyribonucleotides.

    Sudhir Agrawal;Chris Christodoulou;Michael J. Gait

Frequent Co-Authors

Ekambar R. Kandimalla
Ekambar R. Kandimalla Takeda (United States)
Paul C. Zamecnik
Paul C. Zamecnik Harvard University
Hui Wang
Hui Wang Chinese Academy of Sciences
Fortunato Ciardiello
Fortunato Ciardiello University of Campania "Luigi Vanvitelli"
Giampaolo Tortora
Giampaolo Tortora University of Verona
Robert B. Diasio
Robert B. Diasio Mayo Clinic
John Mendelsohn
John Mendelsohn The University of Texas at Austin
Alan Pollack
Alan Pollack University of Miami
Thoru Pederson
Thoru Pederson University of Massachusetts Chan Medical School
Stefano Pepe
Stefano Pepe University of Salerno

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