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Biology and Biochemistry

D-Index
64
Citations
18148
World Ranking
9518
National Ranking
4202

Research.com Recognitions

  • 1991 - US President's National Medal of Science "For his pioneering research of protein biosynthesis, opening the door to biochemical attack, and paving the way for dissection of the genetic code; and for introducing the concept and method of antisense DNA as an approach to viral gene inhibition and chemotherapy.", Presented by President Bush at a White House Rose Garden Ceremony on September 16, 1991.
  • 1974 - Member of the National Academy of Medicine (NAM)
  • 1968 - Member of the National Academy of Sciences
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Paul C. Zamecnik was affiliated with Harvard University in the United States. Their work contributed to the field of molecular biology and genetics, particularly in the foundational understanding of protein biosynthesis.

While specific details about papers, coauthors, or publication venues are not available, the scientist was recognized by several prestigious institutions throughout their career.

  • US President's National Medal of Science, 1991, awarded for pioneering research on protein biosynthesis, contributions to biochemical attacks, dissection of the genetic code, and the introduction of antisense DNA methods in viral gene inhibition and chemotherapy.
  • Member of the National Academy of Medicine (NAM), 1974.
  • Member of the National Academy of Sciences, 1968.
  • Member of the Association of American Physicians.

These honors reflect recognition from the scientific community for contributions to molecular biology and medical research, particularly regarding genetic code analysis and biochemical methods.

Details about their fields of study, subfields, main topics of work, frequent collaborators, recent papers, publication venues, and book publications are not documented in the available data.

Paul C. Zamecnik is deceased. Their academic and scientific legacy remains tied to early advancements in understanding protein biosynthesis and genetic mechanisms at Harvard University and in the broader research community.

Best Publications

  • Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide

    Mary L. Stephenson;Paul C. Zamecnik

  • Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer

    Richard A. Cardullo;Sudhir Agrawal;Carlos Flores;Paul C. Zamecnik

  • Enzymatic carboxyl activation of amino acids.

    Mahlon B. Hoagland;Elizabeth B. Keller;Paul C. Zamecnik

  • Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA

    Paul C. Zamecnik;John Goodchild;Yoshi Taguchi;Prem S. Sarin

  • The effect of guanosine diphosphate and triphosphate on the incorporation of labeled amino acids into proteins.

    Elizabeth B. Keller;Paul C. Zamecnik

  • Studies on cytoplasmic ribonucleoprotein particles from the liver of the rat.

    John W. Littlefield;Elizabeth B. Keller;Jerome Gross;Paul C. Zamecnik

  • Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus

    Sudhir Agrawal;John Goodchild;Maria P. Civeira;Arthur H. Thornton

  • Method of site-specific alteration of RNA and production of encoded polypeptides

    Thoru Pederson;Sudhir Agrawal;Sandra Mayrand;Paul C. Zamecnik

  • Relation between phosphate energy donors and incorporation of labeled amino acids into proteins.

    Paul C. Zamecnik;Elizabeth B. Keller

  • The effect of puromycin on rabbit reticulocyte ribosomes.

    David W. Allen;Paul C. Zamecnik

  • Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates.

    Prem S. Sarin;Sudhir Agrawal;Maria P. Civeira;John Goodchild

  • The preparation and some properties of a low molecular weight ribonucleic acid from baker's yeast.

    R. Monier;M.L. Stephenson;P.C. Zamecnik

  • Inhibition of htlv-iii by exogenous oligonucleotides

    John Goodchild;Paul C. Zamecnik

  • Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator"

    Eliezer Rapaport;Paul C. Zamecnik

  • Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides.

    John Goodchild;Sudhir Agrawal;Maria P. Civeira;Prem S. Sarin

  • Inhibition of human immunodeficiency virus in early infected and chronically infected cells by antisense oligodeoxynucleotides and their phosphorothioate analogues

    Sudhir Agrawal;Tohru Ikeuchi;Daisy Sun;Prem S. Sarin

  • Nucleoside Triphosphates as Precursors of Ribonucleic Acid End Groups in a Mammalian System

    Liselotte I. Hecht;Paul C. Zamecnik;Mary L. Stephenson;Jesse F. Scott

  • Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides.

    Sudhir Agrawal;Sandra H. Mayrand;Paul C. Zamecnik;Thoru Pederson

  • Diadenosine 5', 5'″-P1, P4-tetraphosphate (Ap4A): its role in cellular metabolism

    Paul Zamecnik

  • ON THE STABILITY OF AMINOACYL-S-RNA TO NUCLEOPHILIC CATALYSIS.

    P.S. Sarin;P.C. Zamecnik

Frequent Co-Authors

Sudhir Agrawal
Sudhir Agrawal University of Massachusetts Chan Medical School
Thoru Pederson
Thoru Pederson University of Massachusetts Chan Medical School
Peter Palese
Peter Palese Icahn School of Medicine at Mount Sinai
Marcus A. Horwitz
Marcus A. Horwitz University of California, Los Angeles
Horacio F. Cantiello
Horacio F. Cantiello Harvard University
Alexei A. Bogdanov
Alexei A. Bogdanov University of Massachusetts Chan Medical School
Fritz Lipmann
Fritz Lipmann Harvard University
Robert C. Gallo
Robert C. Gallo University of South Florida
Bert L. Vallee
Bert L. Vallee Harvard University
Stephen J. O'Brien
Stephen J. O'Brien Nova Southeastern University

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