World's Best Scientists 2026 revealed!

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Microbiology

D-Index
83
Citations
23688
World Ranking
998
National Ranking
456

Research.com Recognitions

  • 1999 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1991 - Oswald Avery Award, Infectious Diseases Society of America

Overview

Marcus A. Horwitz is affiliated with the University of California, Los Angeles in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, focusing particularly on infectious diseases and molecular biology subfields.

The scientific work of Marcus A. Horwitz covers key topics including:

  • Bacillus and Francisella bacterial research
  • Tuberculosis research and epidemiology
  • SARS-CoV-2 and COVID-19 research
  • Viral infections and outbreaks research
  • Mycobacterium research and diagnosis
  • Immune responses and vaccinations
  • Yersinia bacterium, plague, and ectoparasites research

Among their recent papers are:

  • "Replicating bacterium-vectored vaccine expressing SARS-CoV-2 Membrane and Nucleocapsid proteins protects against severe COVID-19-like disease in hamsters," 2021, published in npj Vaccines
  • "Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection," 2021, published in Immunity
  • "Oral Administration of Universal Bacterium-Vectored Nucleocapsid-Expressing COVID-19 Vaccine is Efficacious in Hamsters," 2023, published in Microbiology Spectrum
  • "Listeria-vectored multi-antigenic tuberculosis vaccine protects C57BL/6 and BALB/c mice and guinea pigs against Mycobacterium tuberculosis challenge," 2022, published in Communications Biology
  • "Efficacy and safety of an innovative short-course regimen containing clofazimine for treatment of drug-susceptible tuberculosis: a clinical trial," 2023, published in Emerging Microbes & Infections

Frequent coauthors collaborating with Marcus A. Horwitz include:

  • Saša Masleša-Galić
  • Qingmei Jia
  • Bai-Yu Lee
  • Daniel L. Clemens
  • Richard A. Bowen

Common publication venues for their work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • Human Vaccines & Immunotherapeutics
  • npj Vaccines
  • Immunity

Their primary fields of study include medicine with 24 publications and biochemistry, genetics, and molecular biology with 14 publications. In terms of subfields, their focus is on infectious diseases (16 publications), molecular biology (10 publications), epidemiology (6 publications), immunology (5 publications), and genetics (3 publications).

Marcus A. Horwitz has been recognized with professional awards such as the Fellow of the American Association for the Advancement of Science (AAAS) in 1999 and the Oswald Avery Award from the Infectious Diseases Society of America in 1991.

Best Publications

  • Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited.

    D L Clemens;M A Horwitz

  • The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes.

    M A Horwitz

  • Legionnaires' Disease Bacterium (Legionella pneumophila) Multiplies Intracellularly in Human Monocytes

    Marcus A. Horwitz;Samuel C. Silverstein

  • Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes.

    Marcus A. Horwitz

  • Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3.

    L S Schlesinger;C G Bellinger-Kawahara;N R Payne;M A Horwitz

  • Recombinant bacillus Calmette–Guérin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model

    Marcus A. Horwitz;Günter Harth;Barbara Jane Dillon;Saša Masleša-Galić

  • Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis.

    Marcus A. Horwitz;Byong-Wha Esther Lee;Barbara Jane Dillon;Gunter Harth

  • Legionella pneumophila inhibits acidification of its phagosome in human monocytes.

    M A Horwitz;F R Maxfield

  • Virulent and Avirulent Strains of Francisella tularensis Prevent Acidification and Maturation of Their Phagosomes and Escape into the Cytoplasm in Human Macrophages

    Daniel L. Clemens;Bai-Yu Lee;Marcus A. Horwitz

  • Phagocytosis of the legionnaires' disease bacterium (legionella pneumophila) occurs by a novel mechanism: Engulfment within a Pseudopod coil

    Marcus A. Horwitz

  • The Mycobacterium tuberculosis phagosome interacts with early endosomes and is accessible to exogenously administered transferrin.

    Daniel L. Clemens;Marcus A. Horwitz

  • Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages.

    Andrea Marra;Steven J. Blander;Marcus A. Horwitz;Howard A. Shuman

  • Phagocytosis of Legionella pneumophila is mediated by human monocyte complement receptors.

    N R Payne;M A Horwitz

  • Immunization with extracellular proteins of Mycobacterium tuberculosis induces cell-mediated immune responses and substantial protective immunity in a guinea pig model of pulmonary tuberculosis.

    P G Pal;M A Horwitz

  • Influence of the Escherichia coli capsule on complement fixation and on phagocytosis and killing by human phagocytes.

    Marcus A. Horwitz;Samuel C. Silverstein

  • Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone.

    T W Nash;D M Libby;M A Horwitz

  • Francisella tularensis enters macrophages via a novel process involving pseudopod loops.

    Daniel L. Clemens;Bai-Yu Lee;Marcus A. Horwitz

  • A New Vaccine against Tuberculosis Affords Greater Survival after Challenge than the Current Vaccine in the Guinea Pig Model of Pulmonary Tuberculosis

    Marcus A Horwitz;Guenter Harth

  • Exochelins of Mycobacterium tuberculosis remove iron from human iron-binding proteins and donate iron to mycobactins in the M. tuberculosis cell wall.

    J Gobin;M A Horwitz

  • Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas

    Jackson G. Egen;Antonio Gigliotti Rothfuchs;Carl G. Feng;Marcus A. Horwitz

  • The cutaneous infiltrates of leprosy: cellular characteristics and the predominant T-cell phenotypes.

    Van Voorhis Wc;Kaplan G;Sarno En;Horwitz Ma

Frequent Co-Authors

Jeffrey I. Zink
Jeffrey I. Zink University of California, Los Angeles
Bradford W. Gibson
Bradford W. Gibson Buck Institute for Research on Aging
Samuel C. Silverstein
Samuel C. Silverstein Columbia University
Richard A. Bowen
Richard A. Bowen Colorado State University
David G. Brooks
David G. Brooks University of Toronto
Howard A. Shuman
Howard A. Shuman University of Chicago
Zanvil A. Cohn
Zanvil A. Cohn Rockefeller University
Chih-Ming Ho
Chih-Ming Ho University of California, Los Angeles
Andre E. Nel
Andre E. Nel University of California, Los Angeles
Paul C. Zamecnik
Paul C. Zamecnik Harvard University

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