His primary scientific interests are in Microbiology, Mycobacterium tuberculosis, Phagocytosis, Mannose receptor and Receptor. His Microbiology research is multidisciplinary, relying on both Complement system, Complement receptor, Macrophage and Lipoarabinomannan. He has researched Mycobacterium tuberculosis in several fields, including Immune system, Immunology, Mycobacterium and Alveolar macrophage.
His work carried out in the field of Phagocytosis brings together such families of science as Zymosan, Protein A and Virulence. His studies in Receptor integrate themes in fields like Molecular biology and Antibody opsonization. His Molecular biology study which covers Cell biology that intersects with Surfactant protein A and Innate immune system.
His primary areas of investigation include Microbiology, Mycobacterium tuberculosis, Immunology, Immune system and Tuberculosis. His work deals with themes such as Francisella tularensis, Macrophage and Lipoarabinomannan, which intersect with Microbiology. His Mycobacterium tuberculosis study integrates concerns from other disciplines, such as Pathogen, Mycobacterium, Virology, Intracellular and Alveolar macrophage.
Larry S. Schlesinger interconnects Granuloma and Disease in the investigation of issues within Immune system. His Tuberculosis study integrates concerns from other disciplines, such as Diabetes mellitus, Type 2 diabetes and Immunity. His Phagocytosis research incorporates elements of Receptor, Mannose receptor and Complement system, Complement receptor.
Larry S. Schlesinger spends much of his time researching Mycobacterium tuberculosis, Immunology, Immune system, Tuberculosis and Microbiology. His studies in Mycobacterium tuberculosis integrate themes in fields like Autophagy, Phagosome, Phagocytosis, Surfactant protein A and Virulence. His research in Immunology intersects with topics in Latent tuberculosis, Lung and Macaque.
His Immune system study also includes
Larry S. Schlesinger mainly investigates Immunology, Mycobacterium tuberculosis, Immune system, Tuberculosis and Microbiology. Larry S. Schlesinger is studying Innate immune system, which is a component of Immunology. His Mycobacterium tuberculosis research integrates issues from Surfactant protein A, Pulmonary Surfactant-Associated Protein A, Pulmonary surfactant, Lipid metabolism and Macrophage.
The various areas that Larry S. Schlesinger examines in his Immune system study include Latent tuberculosis, Cytokine, Disease, Lung and Granuloma. The study incorporates disciplines such as Epidemiology, Family medicine, Alternative medicine and Public health, Population health in addition to Tuberculosis. His Pathogen study in the realm of Microbiology interacts with subjects such as Scavenger receptor.
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Macrophage phagocytosis of virulent but not attenuated strains of Mycobacterium tuberculosis is mediated by mannose receptors in addition to complement receptors.
L S Schlesinger.
Journal of Immunology (1993)
Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3.
L S Schlesinger;C G Bellinger-Kawahara;N R Payne;M A Horwitz.
Journal of Immunology (1990)
The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis
Peter B. Kang;Abul K. Azad;Jordi B. Torrelles;Thomas M. Kaufman.
Journal of Experimental Medicine (2005)
Binding of the terminal mannosyl units of lipoarabinomannan from a virulent strain of Mycobacterium tuberculosis to human macrophages.
L S Schlesinger;S R Hull;T M Kaufman.
Journal of Immunology (1994)
Pulmonary surfactant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis by a direct interaction with human macrophages.
C D Gaynor;F X McCormack;D R Voelker;S E McGowan.
Journal of Immunology (1995)
Innate Immune Gene Polymorphisms in Tuberculosis
Abul K. Azad;Wolfgang Sadee;Larry S. Schlesinger.
Infection and Immunity (2012)
Surfactant Protein D Binds to Mycobacterium tuberculosis Bacilli and Lipoarabinomannan via Carbohydrate-Lectin Interactions Resulting in Reduced Phagocytosis of the Bacteria by Macrophages1
J. Scott Ferguson;Dennis R. Voelker;Francis X. McCormack;Larry S. Schlesinger.
Journal of Immunology (1999)
Virulent Strains of Helicobacter pylori Demonstrate Delayed Phagocytosis and Stimulate Homotypic Phagosome Fusion in Macrophages
Lee-Ann H. Allen;Larry S. Schlesinger;Byoung Kang.
Journal of Experimental Medicine (2000)
Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b
Murugesan V. S. Rajaram;Bin Ni;Jessica D. Morris;Michelle N. Brooks.
Proceedings of the National Academy of Sciences of the United States of America (2011)
Modeling the Mycobacterium tuberculosis Granuloma - the Critical Battlefield in Host Immunity and Disease.
Evelyn Guirado;Larry S. Schlesinger.
Frontiers in Immunology (2013)
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