D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 65 Citations 14,721 184 World Ranking 1918 National Ranking 938

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

His primary scientific interests are in Immunology, Cell biology, Caspase 1, Inflammation and Inflammasome. His work carried out in the field of Immunology brings together such families of science as Respiratory disease, Bronchoalveolar lavage, Lung and Risk factor. His work deals with themes such as Interleukin, Innate immune system and Biochemistry, which intersect with Cell biology.

His work on NF-κB and Proinflammatory cytokine as part of general Inflammation research is frequently linked to Zinc deficiency, bridging the gap between disciplines. His Inflammasome research is multidisciplinary, relying on both Secretion, Flagellin, Intracellular parasite and Microbiology. As part of one scientific family, Mark D. Wewers deals mainly with the area of Caspase, narrowing it down to issues related to the Molecular biology, and often Monocyte.

His most cited work include:

  • Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria (788 citations)
  • Replacement Therapy for Alpha1-Antitrypsin Deficiency Associated with Emphysema (513 citations)
  • A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release. (365 citations)

What are the main themes of his work throughout his whole career to date?

Mark D. Wewers mainly focuses on Immunology, Cell biology, Monocyte, Molecular biology and Internal medicine. The various areas that Mark D. Wewers examines in his Immunology study include Respiratory disease, Bronchoalveolar lavage and Lung. The concepts of his Cell biology study are interwoven with issues in Apoptosis and Inflammasome, Caspase 1.

His study in Monocyte is interdisciplinary in nature, drawing from both Peripheral blood mononuclear cell, Macrophage and Cytokine. Mark D. Wewers focuses mostly in the field of Molecular biology, narrowing it down to matters related to Receptor and, in some cases, Immune system. Mark D. Wewers has included themes like Gastroenterology and Endocrinology in his Internal medicine study.

He most often published in these fields:

  • Immunology (40.78%)
  • Cell biology (23.79%)
  • Monocyte (20.39%)

What were the highlights of his more recent work (between 2012-2021)?

  • Immunology (40.78%)
  • Lung (14.08%)
  • Cell biology (23.79%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, Lung, Cell biology, Inflammasome and Internal medicine. His biological study spans a wide range of topics, including Bronchoalveolar lavage and Cotinine. His Lung research includes elements of Cancer, Clinical trial, Homeostasis, Neutrophil elastase and Proinflammatory cytokine.

The Cell biology study combines topics in areas such as Receptor, Respiratory epithelium and CARD domain. Mark D. Wewers studies Caspase 1 which is a part of Inflammasome. His work in Internal medicine covers topics such as Endocrinology which are related to areas like Alpha 1-antitrypsin deficiency, Respiratory disease and Alpha.

Between 2012 and 2021, his most popular works were:

  • Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI (215 citations)
  • ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB. (183 citations)
  • Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function (126 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

His primary scientific interests are in Immunology, Inflammasome, Innate immune system, Alpha and Microbiology. His research in the fields of Inflammation overlaps with other disciplines such as Vitamin E Acetate. His work in Inflammasome addresses issues such as Cell biology, which are connected to fields such as Priming.

He combines subjects such as Tularemia, NF-κB, IκB kinase and Virulence with his study of Innate immune system. His Alpha study combines topics in areas such as Endocrinology, Tasa, Lung and Chemotherapy. His Microbiology research incorporates themes from Virology, Francisella tularensis, Francisella, Immune system and Proinflammatory cytokine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

Edward A Miao;Irina A Leaf;Piper M Treuting;Dat P Mao.
Nature Immunology (2010)

1194 Citations

Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema.

M D Wewers;M A Casolaro;S E Sellers;S C Swayze.
The New England Journal of Medicine (1987)

723 Citations

A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release.

Andreas Elssner;Michelle Duncan;Mikhail Gavrilin;Mark D. Wewers.
Journal of Immunology (2004)

526 Citations

Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI

Benjamin C Blount;Mateusz P Karwowski;Peter G Shields;Maria Morel-Espinosa.
The New England Journal of Medicine (2020)

518 Citations

Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia

Mohamed Lamkanfi;Mohamed Lamkanfi;Mohamed Lamkanfi;Anasuya Sarkar;Lieselotte Vande Walle;Lieselotte Vande Walle;Alberto C. Vitari.
Journal of Immunology (2010)

474 Citations

Increased susceptibility to pulmonary emphysema among HIV-seropositive smokers.

Philip T. Diaz;Mark A. King;Eric R. Pacht;Mark D. Wewers.
Annals of Internal Medicine (2000)

370 Citations

Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-κB through the suppression of p65 phosphorylation

Courtney Nicholas;Sanjay Batra;Melissa A. Vargo;Oliver H. Voss.
Journal of Immunology (2007)

353 Citations

Phagocytosis mediated by three distinct Fc gamma receptor classes on human leukocytes.

C. L. Anderson;Li Shen;D. M. Eicher;M. D. Wewers.
Journal of Experimental Medicine (1990)

329 Citations

ATP-stimulated Release of Interleukin (IL)-1β and IL-18 Requires Priming by Lipopolysaccharide and Is Independent of Caspase-1 Cleavage *

Veela B. Mehta;Judith Hart;Mark D. Wewers.
Journal of Biological Chemistry (2001)

328 Citations

Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome.

Mark W. Hall;Mark W. Hall;Nina L. Knatz;Carol Vetterly;Steven Tomarello.
Intensive Care Medicine (2011)

291 Citations

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