His primary scientific interests are in Immunology, Cell biology, Caspase 1, Inflammation and Inflammasome. His work carried out in the field of Immunology brings together such families of science as Respiratory disease, Bronchoalveolar lavage, Lung and Risk factor. His work deals with themes such as Interleukin, Innate immune system and Biochemistry, which intersect with Cell biology.
His work on NF-κB and Proinflammatory cytokine as part of general Inflammation research is frequently linked to Zinc deficiency, bridging the gap between disciplines. His Inflammasome research is multidisciplinary, relying on both Secretion, Flagellin, Intracellular parasite and Microbiology. As part of one scientific family, Mark D. Wewers deals mainly with the area of Caspase, narrowing it down to issues related to the Molecular biology, and often Monocyte.
Mark D. Wewers mainly focuses on Immunology, Cell biology, Monocyte, Molecular biology and Internal medicine. The various areas that Mark D. Wewers examines in his Immunology study include Respiratory disease, Bronchoalveolar lavage and Lung. The concepts of his Cell biology study are interwoven with issues in Apoptosis and Inflammasome, Caspase 1.
His study in Monocyte is interdisciplinary in nature, drawing from both Peripheral blood mononuclear cell, Macrophage and Cytokine. Mark D. Wewers focuses mostly in the field of Molecular biology, narrowing it down to matters related to Receptor and, in some cases, Immune system. Mark D. Wewers has included themes like Gastroenterology and Endocrinology in his Internal medicine study.
His primary areas of investigation include Immunology, Lung, Cell biology, Inflammasome and Internal medicine. His biological study spans a wide range of topics, including Bronchoalveolar lavage and Cotinine. His Lung research includes elements of Cancer, Clinical trial, Homeostasis, Neutrophil elastase and Proinflammatory cytokine.
The Cell biology study combines topics in areas such as Receptor, Respiratory epithelium and CARD domain. Mark D. Wewers studies Caspase 1 which is a part of Inflammasome. His work in Internal medicine covers topics such as Endocrinology which are related to areas like Alpha 1-antitrypsin deficiency, Respiratory disease and Alpha.
His primary scientific interests are in Immunology, Inflammasome, Innate immune system, Alpha and Microbiology. His research in the fields of Inflammation overlaps with other disciplines such as Vitamin E Acetate. His work in Inflammasome addresses issues such as Cell biology, which are connected to fields such as Priming.
He combines subjects such as Tularemia, NF-κB, IκB kinase and Virulence with his study of Innate immune system. His Alpha study combines topics in areas such as Endocrinology, Tasa, Lung and Chemotherapy. His Microbiology research incorporates themes from Virology, Francisella tularensis, Francisella, Immune system and Proinflammatory cytokine.
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Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
Edward A Miao;Irina A Leaf;Piper M Treuting;Dat P Mao.
Nature Immunology (2010)
Replacement therapy for alpha 1-antitrypsin deficiency associated with emphysema.
M D Wewers;M A Casolaro;S E Sellers;S C Swayze.
The New England Journal of Medicine (1987)
A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release.
Andreas Elssner;Michelle Duncan;Mikhail Gavrilin;Mark D. Wewers.
Journal of Immunology (2004)
Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI
Benjamin C Blount;Mateusz P Karwowski;Peter G Shields;Maria Morel-Espinosa.
The New England Journal of Medicine (2020)
Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia
Mohamed Lamkanfi;Mohamed Lamkanfi;Mohamed Lamkanfi;Anasuya Sarkar;Lieselotte Vande Walle;Lieselotte Vande Walle;Alberto C. Vitari.
Journal of Immunology (2010)
Increased susceptibility to pulmonary emphysema among HIV-seropositive smokers.
Philip T. Diaz;Mark A. King;Eric R. Pacht;Mark D. Wewers.
Annals of Internal Medicine (2000)
Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-κB through the suppression of p65 phosphorylation
Courtney Nicholas;Sanjay Batra;Melissa A. Vargo;Oliver H. Voss.
Journal of Immunology (2007)
Phagocytosis mediated by three distinct Fc gamma receptor classes on human leukocytes.
C. L. Anderson;Li Shen;D. M. Eicher;M. D. Wewers.
Journal of Experimental Medicine (1990)
ATP-stimulated Release of Interleukin (IL)-1β and IL-18 Requires Priming by Lipopolysaccharide and Is Independent of Caspase-1 Cleavage *
Veela B. Mehta;Judith Hart;Mark D. Wewers.
Journal of Biological Chemistry (2001)
Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome.
Mark W. Hall;Mark W. Hall;Nina L. Knatz;Carol Vetterly;Steven Tomarello.
Intensive Care Medicine (2011)
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