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Medicine

D-Index
159
Citations
110183
World Ranking
807
National Ranking
454

Research.com Recognitions

  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Michael A. Caligiuri is affiliated with the City Of Hope National Medical Center in the United States. Their research extensively covers medicine, immunology and microbiology, and biochemistry, genetics, and molecular biology. The main subfields of their work include immunology, oncology, molecular biology, genetics, and infectious diseases.

The scientist focuses on several key topics within their research portfolio. These include immune cell function and interaction, CAR-T cell therapy research, IL-33, ST2, and ILC pathways, virus-based gene therapy research, SARS-CoV-2 and COVID-19 research, T-cell and B-cell immunology, and immunotherapy and immune responses.

Frequent publication venues for their work include:

  • Cancer Research
  • Blood
  • The Journal of Immunology
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)

Key collaborators in their scientific endeavors include Jianhua Yu, Jianying Zhang, Anthony G. Mansour, Guido Marcucci, and Tasha Barr.

Significant recent papers authored or co-authored by Michael A. Caligiuri include:

  • The emerging field of oncolytic virus-based cancer immunotherapy, 2022, Trends in cancer
  • Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses, 2021, Cell Reports Medicine
  • The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity, 2021, The Journal of Experimental Medicine
  • YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8+ T cells, 2023, Nature Immunology
  • An Oncolytic Virus Expressing IL15/IL15Rα Combined with Off-the-Shelf EGFR-CAR NK Cells Targets Glioblastoma, 2021, Cancer Research

The scientist has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2003.

Best Publications

  • Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.

    T. R. Golub;T. R. Golub;D. K. Slonim;P. Tamayo;C. Huard

  • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

    Tsvee Lapidot;Christian Sirard;Josef Vormoor;Barbara Murdoch

  • The biology of human natural killer-cell subsets.

    Megan A Cooper;Todd A Fehniger;Michael A Caligiuri

  • Innate or Adaptive Immunity? The Example of Natural Killer Cells

    Eric Vivier;David H. Raulet;Alessandro Moretta;Michael A. Caligiuri

  • Human natural killer cells

    Michael A. Caligiuri

  • Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset

    Megan A. Cooper;Todd A. Fehniger;Sarah C. Turner;Kenneth S. Chen

  • Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

    Joseph F. Costello;Joseph F. Costello;Michael C. Frühwald;Michael C. Frühwald;Dominic J. Smiraglia;Laura J. Rush

  • MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

    Muller Fabbri;Alessio Paone;Federica Calore;Roberta Galli

  • Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor.

    William E. Carson;Judith G. Giri;Matthew J. Lindemann;Michael L. Linett

  • Interleukin 15: biology and relevance to human disease

    Todd A. Fehniger;Michael A. Caligiuri

  • CD56bright natural killer cells are present in human lymph nodes and are activated by T cell–derived IL-2: a potential new link between adaptive and innate immunity

    Todd A Fehniger;Megan A Cooper;Gerard J Nuovo;Marina Cella

  • Differential Cytokine and Chemokine Gene Expression by Human NK Cells Following Activation with IL-18 or IL-15 in Combination with IL-12: Implications for the Innate Immune Response

    Todd A. Fehniger;Manisha H. Shah;Matthew J. Turner;Jeffrey B. VanDeusen

  • The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody

    Don M. Benson;Courtney E. Bakan;Anjali Mishra;Craig C. Hofmeister

  • IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

    Guido Marcucci;Kati Maharry;Yue-Zhong Wu;Michael D. Radmacher

  • Absence of the Wild-Type Allele Predicts Poor Prognosis in Adult de Novo Acute Myeloid Leukemia with Normal Cytogenetics and the Internal Tandem Duplication of FLT3 A Cancer and Leukemia Group B Study

    Susan P. Whitman;Kellie J. Archer;Lan Feng;Claudia Baldus

  • Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

    Shu Hao Hsu;Bo Wang;Janaiah Kota;Jianhua Yu

  • Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes.

    Jason A. Dubovsky;Kyle A. Beckwith;Gayathri Natarajan;Jennifer A. Woyach

  • Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection.

    Khuong B. Nguyen;Thais P. Salazar-Mather;Marc Y Dalod;Jeffrey B. Van Deusen

  • Obesity, Inflammation, and Cancer

    Tuo Deng;Christopher J. Lyon;Stephen Bergin;Michael A. Caligiuri

  • Natural killer cell receptors: new biology and insights into the graft-versus-leukemia effect.

    Sherif S. Farag;Todd A. Fehniger;Todd A. Fehniger;Loredana Ruggeri;Loredana Ruggeri;Andrea Velardi;Andrea Velardi

Frequent Co-Authors

Guido Marcucci
Guido Marcucci City Of Hope National Medical Center
Jianhua Yu
Jianhua Yu City Of Hope National Medical Center
Clara D. Bloomfield
Clara D. Bloomfield The Ohio State University
Susan P. Whitman
Susan P. Whitman The Ohio State University
John C. Byrd
John C. Byrd University of Pittsburgh Cancer Institute
Krzysztof Mrózek
Krzysztof Mrózek The Ohio State University
Richard A. Larson
Richard A. Larson University of Chicago
Bayard L. Powell
Bayard L. Powell Wake Forest University
Jonathan E. Kolitz
Jonathan E. Kolitz Hofstra University
Shujun Liu
Shujun Liu University of Minnesota

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