Kenya Shitara

Overview

Best Publications

• The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity.

  Toyohide Shinkawa;Kazuyasu Nakamura;Naoko Yamane;Emi Shoji-Hosaka

  2593
  Citations

• Establishment of FUT8 knockout Chinese hamster ovary cells: an ideal host cell line for producing completely defucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity.

  Naoko Yamane-Ohnuki;Satoko Kinoshita;Miho Inoue-Urakubo;Machi Kusunoki

  1135
  Citations

• Composition of antibody specifically binding to cd20

  Kenya Shitara;Mikiko Sakurada;Kazuhisa Uchida;Toyohide Shinkawa

  844
  Citations

• Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans

  Asako Sawano;Shinobu Iwai;Yoshiko Sakurai;Mikito Ito

  718
  Citations

• Fucose Depletion from Human IgG1 Oligosaccharide Enhances Binding Enthalpy and Association Rate Between IgG1 and FcγRIIIa

  Akira Okazaki;Emi Shoji-Hosaka;Kazuyasu Nakamura;Masako Wakitani

  655
  Citations

• Method of enhancing of binding activity of antibody composition to Fcgamma receptor IIIa

  Kazuyasu Nakamura;Kenya Shitara

  652
  Citations

• FUSION TNFR2 PROTEIN COMPOSITION

  Shitara Kenya;Hosaka Emi;Natsume Akito;Wakitani Masako

  645
  Citations

• Process for purifying antibody

  Toyohide Shinkawa;Kazuhisa Uchida;Motoo Yamasaki;Emi Hosaka

  622
  Citations

• Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types.

  Yutaka Kanda;Tsuyoshi Yamada;Katsuhiro Mori;Akira Okazaki

  589
  Citations

• Therapeutic agent for patients having human FcgammaRIIIa

  Kazuyasu Nakamura;Kenya Shitara;Shigeki Hatanaka;Rinpei Niwa

  560
  Citations

• Antibody composition-containing medicament

  Rinpei Niwa;Kenya Shitara

  543
  Citations

• Defucosylated chimeric anti-CC chemokine receptor 4 IgG1 with enhanced antibody-dependent cellular cytotoxicity shows potent therapeutic activity to T-cell leukemia and lymphoma

  Rinpei Niwa;Emi Shoji-Hosaka;Mikiko Sakurada;Toyohide Shinkawa

  519
  Citations

• Medicine containing antibody composition

  Kenya Shitara;Rinpei Niwa

  490
  Citations

• Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells.

  Shinichi Kanno;Nobuyuki Oda;Mayumi Abe;Yoshito Terai

  410
  Citations

• IgG subclass-independent improvement of antibody-dependent cellular cytotoxicity by fucose removal from Asn297-linked oligosaccharides.

  Rinpei Niwa;Akito Natsume;Aya Uehara;Masako Wakitani

  373
  Citations

• Structural comparison of fucosylated and nonfucosylated Fc fragments of human immunoglobulin G1.

  Shigeki Matsumiya;Yoshiki Yamaguchi;Jun-ichi Saito;Mayumi Nagano

  343
  Citations

• Engineered Antibodies of IgG1/IgG3 Mixed Isotype with Enhanced Cytotoxic Activities

  Akito Natsume;Mika In;Hiroyuki Takamura;Tomoaki Nakagawa

  335
  Citations

• Nonfucosylated Therapeutic IgG1 Antibody Can Evade the Inhibitory Effect of Serum Immunoglobulin G on Antibody-Dependent Cellular Cytotoxicity through its High Binding to FcγRIIIa

  Shigeru Iida;Hirofumi Misaka;Miho Inoue;Mami Shibata

  309
  Citations

• Non-fucosylated therapeutic antibodies as next-generation therapeutic antibodies

  Mitsuo Satoh;Shigeru Iida;Kenya Shitara

  305
  Citations

• Defucosylated Humanized Anti-CCR4 Monoclonal Antibody KW-0761 as a Novel Immunotherapeutic Agent for Adult T-cell Leukemia/Lymphoma

  Toshihiko Ishii;Takashi Ishida;Atae Utsunomiya;Atsushi Inagaki

  304
  Citations