World's Best Scientists 2026 revealed!
Kazumitsu Ueda

Kazumitsu Ueda

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
27614
World Ranking
4703
National Ranking
309

Overview

Kazumitsu Ueda is affiliated with Kyoto University in Japan and has contributed extensively to the fields of medicine, biochemistry, genetics, and molecular biology. Their research spans a variety of subfields including molecular biology, surgery, oncology, pulmonary and respiratory medicine, and genetics.

The main topics covered by their work include drug transport and resistance mechanisms, cholesterol and lipid metabolism, lipid metabolism and biosynthesis, CRISPR and genetic engineering, lipid membrane structure and behavior, trace elements in health, and RNA interference and gene delivery.

Kazumitsu Ueda's frequent co-authors include Noriyuki Kioka, Ryota Futamata, Yasuhisa Kimura, Fumihiko Ogasawara, and Atsushi Kodan. This network of collaborators reflects their involvement within specialized research communities focused on molecular and cellular biology.

The scientist has published in several prominent venues, with the most publications appearing in FEBS Letters and the Journal of Biological Chemistry. Other venues include Nihon Gekakei Rengo Gakkaishi (Journal of Japanese College of Surgeons), The FASEB Journal, and The American Journal of Surgery.

Recent papers authored or co-authored by Kazumitsu Ueda include:

  • Structural and functional diversity calls for a new classification of ABC transporters, 2020, FEBS Letters
  • ABCB1/MDR1/P-gp employs an ATP-dependent twist-and-squeeze mechanism to export hydrophobic drugs, 2020, FEBS Letters
  • ABCA13 dysfunction associated with psychiatric disorders causes impaired cholesterol trafficking, 2020, Journal of Biological Chemistry
  • ABC proteins in evolution, 2020, FEBS Letters
  • In vivo FRET analyses reveal a role of ATP hydrolysis-associated conformational changes in human P-glycoprotein, 2020, Journal of Biological Chemistry

Best Publications

  • Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

    Chang jie Chen;Janice E. Chin;Kazumitsu Ueda;Douglas P. Clark

  • Expression of a multidrug-resistance gene in human tumors and tissues

    A T Fojo;K Ueda;D J Slamon;D G Poplack

  • Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

    Kazumitsu Ueda;Carol Cardarelli;Michael M. Gottesman;Ira Pastan

  • Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

    Khew-Voon Chin;Kazumitsu Ueda;Ira Pastan;Michael M. Gottesman

  • Human P-glycoprotein transports cyclosporin A and FK506.

    T. Saeki;K. Ueda;Yusuke Tanigawara;R. Hori

  • Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone.

    K. Ueda;N. Okamura;M. Hirai;Yusuke Tanigawara

  • Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.

    Y Ohta;Y Tanizawa;H Inoue;T Hosaka

  • A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells.

    Ira Pastan;Michael M. Gottesman;Kazumitsu Ueda;Elizabeth Lovelace

  • The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

    Kazumitsu Ueda;Marilyn M. Cornwell;Michael M. Gottesman;Ira Pastan

  • The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation.

    K. Ueda;D. P. Clark;Chang-Jie Chen;I. B. Roninson

  • Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).

    Yusuke Tanigawara;N. Okamura;M. Hirai;M. Yasuhara

  • Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

    Shigenobu Kishino;Michiki Takeuchi;Si Bum Park;Akiko Hirata

  • Isolation and sequence of the promoter region of the human multidrug-resistance (P-glycoprotein) gene.

    K Ueda;I Pastan;M M Gottesman

  • Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins.

    Chang-Jie Chen;D. Clark;K. Ueda;I. Pastan

  • Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica.

    Nobukazu Shitan;Ingrid Bazin;Kazuyuki Dan;Kazuaki Obata

  • Vinexin, CAP/ponsin, ArgBP2 : a Novel Adaptor Protein Family Regulating Cytoskeletal Organization and Signal Transduction

    Noriyuki Kioka;Kazumitsu Ueda;Teruo Amachi

  • Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1

    Aya Kobayashi;Yasukazu Takanezawa;Takashi Hirata;Yuji Shimizu

  • Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol.

    Shu Lin Liu;Ren Sheng;Jae Hun Jung;Li Wang

  • P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance.

    Noriyuki Kioka;Jun Tsubota;Yoshiyuki Kakehi;Tohru Komano

  • MgADP Antagonism to Mg2+-independent ATP Binding of the Sulfonylurea Receptor SUR1

    Kazumitsu Ueda;Nobuya Inagaki;Susumu Seino

Frequent Co-Authors

Ira Pastan
Ira Pastan Center for Cancer Research
Shinji Yokoyama
Shinji Yokoyama Chubu University
Nobuya Inagaki
Nobuya Inagaki Kyoto University
Michael M. Gottesman
Michael M. Gottesman National Institutes of Health
Fumihiko Sato
Fumihiko Sato Kyoto University
Frances M. Ashcroft
Frances M. Ashcroft University of Oxford
Hiroyuki Arai
Hiroyuki Arai University of Tokyo
Kazufumi Yazaki
Kazufumi Yazaki Kyoto University
Yoshitomo Oka
Yoshitomo Oka Tohoku University
Masayuki Murata
Masayuki Murata Osaka University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Kazumitsu Ueda

Trending Scientists

Recently Published Articles