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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
38570
World Ranking
2285
National Ranking
65

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award
  • 1994 - Robert L. Noble Prize, Canadian Cancer Society
  • 1991 - Fellow of the Royal Society of Canada Academy of Science
  • 1990 - Canada Gairdner International Award

Overview

Victor Ling is affiliated with the BC Cancer Research Centre in Canada and has contributed extensively to the field of medicine with a focus on hematology, surgery, oncology, genetics, and immunology. Their research has encompassed a range of topics including pediatric hepatobiliary diseases and treatments, acute myeloid leukemia research, drug transport and resistance mechanisms, lymphoma diagnosis and treatment, liver disease diagnosis and treatment, CNS lymphoma diagnosis and treatment, and chronic lymphocytic leukemia research.

The frequent coauthors collaborating with Victor Ling include Mahesh Prahladan, Renxue Wang, Liang Piu Koh, Michelle Richardson, and Andrew Hodson. This collaboration reflects a strong network within the biomedical research community.

The scientist's publications have appeared in multiple venues, with the highest number in:

  • HemaSphere
  • Journal of Clinical and Translational Hepatology
  • Blood
  • Hematological Oncology
  • Journal of Thrombosis and Thrombolysis

Recent papers authored or coauthored by Victor Ling include:

  • An unusual presentation of Idiopathic hypereosinophilic syndrome, 2020, Journal of Thrombosis and Thrombolysis
  • The protective role of hydrophilic tetrahydroxylated bile acids (THBA), 2021, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • Changes in plasma bile acid profiles after partial internal biliary diversion in PFIC2 patients, 2020, Annals of Translational Medicine
  • Neonatal Dubin-Johnson Syndrome and its Differentiation from Biliary Atresia, 2022, Journal of Clinical and Translational Hepatology
  • Poly-hydroxylated bile acids and their prognostic roles in Alagille syndrome, 2023, World Journal of Pediatrics

Victor Ling has been recognized with several awards throughout their career:

  • Robert L. Noble Prize, Canadian Cancer Society, 1994
  • Fellow of the Royal Society of Canada, 1991 (Academy of Science)
  • Canada Gairdner International Award, 1990

Best Publications

  • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants.

    Rudolph L Juliano;V. Ling;V. Ling

  • The biochemistry of P-glycoprotein-mediated multidrug resistance.

    Endicott Ja;Ling

  • Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines.

    Norbert Kartner;John R. Riordan;Victor Ling

  • Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines.

    John R. Riordan;Kathryn Deuchars;Norbert Kartner;Noa Alon

  • Reduced permeability in CHO cells as a mechanism of resistance to colchicine.

    Victor Ling;Larry H. Thompson

  • Mechanism of multidrug resistance.

    Grace Bradley;Peter F. Juranka;Victor Ling

  • Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

    James H. Gerlach;Jane A. Endicott;Peter F. Juranka;Graham Henderson;Graham Henderson

  • A tiling resolution DNA microarray with complete coverage of the human genome.

    Adrian S. Ishkanian;Chad A. Malloff;Spencer K. Watson;Ronald J. DeLeeuw

  • Multidrug resistance: molecular mechanisms and clinical relevance

    Victor Ling

  • P-glycoprotein: multidrug-resistance and a superfamily of membrane-associated transport proteins.

    Peter F. Juranka;Roman L. Zastawny;Victor Ling

  • Positively Cooperative Sites for Drug Transport by P-Glycoprotein with Distinct Drug Specificities

    Adam B. Shapiro;Victor Ling

  • Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood.

    H S Chan;P S Thorner;G Haddad;V Ling

  • P-glycoprotein expression as a predictor of the outcome of therapy for neuroblastoma.

    Helen S.L. Chan;George Haddad;Paul S. Thorner;Gerrit DeBoer

  • The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein

    Kazumitsu Ueda;Marilyn M. Cornwell;Michael M. Gottesman;Ira Pastan

  • Purification of P-glycoprotein from plasma membrane vesicles of Chinese hamster ovary cell mutants with reduced colchicine permeability.

    J R Riordan;V Ling

  • Chemotherapy With Focal Therapy Can Cure Intraocular Retinoblastoma Without Radiotherapy

    Brenda L. Gallie;Andrew Budning;Gerrit DeBoer;Jake J. Thiessen

  • Detection of P-glycoprotein in ovarian cancer: a molecular marker associated with multidrug resistance.

    David R. Bell;James H. Gerlach;Norbert Kartner;Ronald N. Buick

  • Pleiotropic phenotype of colchicine-resistant CHO cells: cross-resistance and collateral sensitivity.

    N. T. Bech-Hansen;J. E. Till;V. Ling

  • Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.

    Adam B. Shapiro;Kelly Fox;Ping Lam;Victor Ling

  • Identification of a sister gene to P-glycoprotein

    Sarah Childs;Richard Lin Yeh;Elias Georges;Victor Ling

Frequent Co-Authors

Richard P. Hill
Richard P. Hill Princess Margaret Cancer Centre
Brenda L. Gallie
Brenda L. Gallie University of Toronto
John R. Riordan
John R. Riordan University of North Carolina at Chapel Hill
Ann F. Chambers
Ann F. Chambers University of Western Ontario
Jane A. Endicott
Jane A. Endicott Newcastle University
Wan L. Lam
Wan L. Lam BC Cancer Research Centre
Stephen Lam
Stephen Lam University of British Columbia
James E. Till
James E. Till Ontario Institute for Cancer Research
Thomas M. Grogan
Thomas M. Grogan Roche (Switzerland)
Marco A. Marra
Marco A. Marra University of British Columbia

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