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Biology and Biochemistry

D-Index
52
Citations
16682
World Ranking
16456
National Ranking
308

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Lucas Pelkmans is affiliated with the University of Zurich in Switzerland. Their research work spans multiple topics in the fields of biochemistry, genetics, and molecular biology, with a strong focus on molecular biology, biophysics, and cell biology.

The scientist's publication record includes 118 items primarily in biochemistry, genetics, and molecular biology, with notable contributions to subfields such as molecular biology (78 publications), biophysics (23), cell biology (10), cancer research (6), and immunology (6). Main topics covered in their research are:

  • Cell Image Analysis Techniques
  • Single-cell and spatial transcriptomics
  • RNA Research and Splicing
  • Cancer Genomics and Diagnostics
  • Gene Regulatory Network Analysis
  • RNA and protein synthesis mechanisms
  • Nuclear Structure and Function

Pelkmans has published frequently in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory) - 15 publications
  • Zenodo (CERN European Organization for Nuclear Research) - 5 publications
  • Nature Communications - 4 publications
  • Nature Methods - 3 publications
  • Science - 2 publications

Recent papers illustrating their research include:

  • The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support, 2021, Cancer Cell
  • Learning single-cell perturbation responses using neural optimal transport, 2023, Nature Methods
  • Multimodal perception links cellular state to decision-making in single cells, 2022, Science
  • Multimodal spatiotemporal phenotyping of human retinal organoid development, 2023, Nature Biotechnology
  • OME-Zarr: a cloud-optimized bioimaging file format with international community support, 2023, Histochemistry and Cell Biology

The scientist frequently collaborates with other researchers, including Gabriele Gut, Jacobo Sarabia del Castillo, Ximena Bonilla, Kjong-Van Lehmann, and Gunnar Rätsch.

Among their distinctions, Lucas Pelkmans has been recognized as a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER.

    Lucas Pelkmans;Jürgen Kartenbeck;Ari Helenius

  • Endocytosis via caveolae.

    Lucas Pelkmans;Ari Helenius

  • Local Actin Polymerization and Dynamin Recruitment in SV40-Induced Internalization of Caveolae

    Lucas Pelkmans;Daniel Püntener;Ari Helenius

  • Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis.

    Lucas Pelkmans;Eugenio Fava;Hannes Grabner;Michael Hannus

  • Caveolin-Stabilized Membrane Domains as Multifunctional Transport and Sorting Devices in Endocytic Membrane Traffic

    Lucas Pelkmans;Thomas Bürli;Marino Zerial;Ari Helenius

  • Not just a sink: endosomes in control of signal transduction.

    Marta Miaczynska;Lucas Pelkmans;Marino Zerial

  • Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling.

    Frank Wippich;Bernd Bodenmiller;Maria Gustafsson Trajkovska;Stefanie Wanka

  • Clathrin- and caveolin-1–independent endocytosis: entry of simian virus 40 into cells devoid of caveolae

    Eva-Maria Damm;Lucas Pelkmans;Jürgen Kartenbeck;Anna Mezzacasa

  • Population context determines cell-to-cell variability in endocytosis and virus infection

    Berend Snijder;Raphael Sacher;Raphael Sacher;Pauli Rämö;Eva-Maria Damm

  • Insider information: what viruses tell us about endocytosis.

    Lucas Pelkmans;Ari Helenius

  • Multiplexed protein maps link subcellular organization to cellular states.

    Gabriele Gut;Markus D. Herrmann;Lucas Pelkmans

  • Origins of regulated cell-to-cell variability.

    Berend Snijder;Lucas Pelkmans;Lucas Pelkmans

  • Kinase-regulated quantal assemblies and kiss-and-run recycling of caveolae

    Lucas Pelkmans;Marino Zerial

  • Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

    Christine Burkard;Monique H. Verheije;Oliver Wicht;Sander I. van Kasteren

  • Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells.

    Mario Schelhaas;Johan Malmström;Lucas Pelkmans;Johannes Haugstetter

  • Control of Transcript Variability in Single Mammalian Cells.

    Nico Battich;Thomas Stoeger;Lucas Pelkmans

  • Kinase-controlled phase transition of membraneless organelles in mitosis.

    Arpan Kumar Rai;Jia-Xuan Chen;Jia-Xuan Chen;Matthias Selbach;Matthias Selbach;Lucas Pelkmans

  • Assembly and trafficking of caveolar domains in the cell caveolae as stable, cargo-triggered, vesicular transporters

    Akiko Tagawa;Anna Mezzacasa;Arnold Hayer;Andrea Longatti

  • Image-based transcriptomics in thousands of single human cells at single-molecule resolution

    Nico Battich;Thomas Stoeger;Lucas Pelkmans

  • Secrets of caveolae- and lipid raft-mediated endocytosis revealed by mammalian viruses.

    Lucas Pelkmans

Frequent Co-Authors

Ari Helenius
Ari Helenius ETH Zurich
Timo Hyypiä
Timo Hyypiä University of Turku
Marino Zerial
Marino Zerial Max Planck Society
Urs F. Greber
Urs F. Greber University of Zurich
Peter J. M. Rottier
Peter J. M. Rottier Utrecht University
Cornelis A. M. de Haan
Cornelis A. M. de Haan Utrecht University
Jean Gruenberg
Jean Gruenberg University of Geneva
Ali Amara
Ali Amara Université Paris Cité

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