D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 77 Citations 25,260 144 World Ranking 2109 National Ranking 41

Research.com Recognitions

Awards & Achievements

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Cell membrane
  • Biochemistry

Jean Gruenberg spends much of his time researching Cell biology, Endosome, Endocytic cycle, Endocytosis and Vesicle. The various areas that Jean Gruenberg examines in his Cell biology study include Membrane and Biochemistry. His Endosome study incorporates themes from Cytoplasm, Lipid bilayer fusion, Late endosome and Membrane transport.

His work carried out in the field of Endocytic cycle brings together such families of science as Biological membrane, GTP', Small GTPase and Cytosol. His Endocytosis research incorporates themes from Cell polarity, Protein targeting and Cell Compartmentation. His Vesicle research is multidisciplinary, relying on both Kinesin, Lysosome, Niemann–Pick disease and Homeostasis.

His most cited work include:

  • rab5 controls early endosome fusion in vitro. (935 citations)
  • Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. (816 citations)
  • A lipid associated with the antiphospholipid syndrome regulates endosome structure and function (672 citations)

What are the main themes of his work throughout his whole career to date?

Jean Gruenberg mainly focuses on Cell biology, Endosome, Endocytic cycle, Endocytosis and Vesicle. His Cell biology research incorporates elements of Membrane, Biochemistry and Membrane transport. His work focuses on many connections between Endosome and other disciplines, such as Lysosome, that overlap with his field of interest in Secretion.

In his research, G protein is intimately related to Rab, which falls under the overarching field of Endocytic cycle. His Endocytosis study combines topics in areas such as Small GTPase, Transmembrane protein, Cholesterol, Intracellular and Internalization. His Vesicle study integrates concerns from other disciplines, such as Golgi apparatus, Vesicular stomatitis virus, Endocytic vesicle and Kinesin.

He most often published in these fields:

  • Cell biology (76.97%)
  • Endosome (65.17%)
  • Endocytic cycle (33.15%)

What were the highlights of his more recent work (between 2010-2020)?

  • Cell biology (76.97%)
  • Endosome (65.17%)
  • Endocytosis (32.58%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Endosome, Endocytosis, Vesicle and ESCRT. His research on Cell biology frequently connects to adjacent areas such as Secretion. Jean Gruenberg combines subjects such as Transport protein, Endocytic cycle and Lysosome with his study of Endosome.

His work deals with themes such as Multivesicular Body, Chloride channel and Signal transduction, MAPK/ERK pathway, which intersect with Endocytic cycle. His Endocytosis course of study focuses on Cholesterol and Phospholipid. His work investigates the relationship between Organelle and topics such as Cell that intersect with problems in Mitochondrial fission and Endoplasmic reticulum.

Between 2010 and 2020, his most popular works were:

  • Endosome maturation, transport and functions. (231 citations)
  • ALIX and the multivesicular endosome: ALIX in Wonderland (185 citations)
  • Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH. (163 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Cell membrane
  • Biochemistry

His primary scientific interests are in Cell biology, Endosome, Endocytosis, Endocytic cycle and ESCRT. His research integrates issues of Biochemistry, Systems biology and Cytosol in his study of Cell biology. His studies deal with areas such as Vesicle, Lysosome, Membrane lipids and Flux as well as Endosome.

Jean Gruenberg studies Late endosome which is a part of Endocytosis. His study in Endocytic cycle is interdisciplinary in nature, drawing from both Signal transducing adaptor protein, Exocytosis, Secretion, LAMP1 and Secretory pathway. Jean Gruenberg combines subjects such as Plasma protein binding and Cell membrane with his study of ESCRT.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

rab5 controls early endosome fusion in vitro.

Jean-Pierre Gorvel;Philippe Chavrier;Marino Zerial;Jean Gruenberg.
Cell (1991)

1286 Citations

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

Harald Alfred Stenmark;Robert G. Parton;Olivia Steele-Mortimer;Anne Lütcke.
The EMBO Journal (1994)

998 Citations

The endocytic pathway: a mosaic of domains

Jean Gruenberg.
Nature Reviews Molecular Cell Biology (2001)

993 Citations

The biogenesis of multivesicular endosomes

Jean Gruenberg;Harald Stenmark.
Nature Reviews Molecular Cell Biology (2004)

822 Citations

A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

T Kobayashi;E Stang;K S Fang;P de Moerloose.
Nature (1998)

795 Citations

Membrane transport in the endocytic pathway

Jean Gruenberg;Frederick R Maxfield.
Current Opinion in Cell Biology (1995)

789 Citations

Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization

Hirotami Matsuo;Julien Chevallier;Nathalie Mayran;Isabelle Le Blanc.
Science (2004)

710 Citations

Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro.

J Gruenberg;G Griffiths;K E Howell.
Journal of Cell Biology (1989)

706 Citations

Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport

Toshihide Kobayashi;Marie-Hélène Beuchat;Margaret Lindsay;Sonia Frias.
Nature Cell Biology (1999)

699 Citations

Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest

Rutilio A. Fratti;Jonathan M. Backer;Jean Gruenberg;Silvia Corvera.
Journal of Cell Biology (2001)

632 Citations

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