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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
29629
World Ranking
3280
National Ranking
70

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jean Gruenberg is a researcher affiliated with the University of Geneva in Switzerland. Their main area of expertise lies within Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology and Cell Biology. The scientist's work extends into related subfields including Physiology, Pathology and Forensic Medicine, and Biomaterials.

The researcher's significant topics of interest include Cellular transport and secretion, Lipid Membrane Structure and Behavior, Extracellular vesicles in disease, Calcium signaling and nucleotide metabolism, Biomedical Research and Pathophysiology, Nanoparticle-Based Drug Delivery, and RNA Interference and Gene Delivery.

Recent publications by Jean Gruenberg include:

  • ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes, 2020, The Journal of Cell Biology
  • Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation, 2020, Nature Cell Biology
  • Nanoparticle entry into cells; the cell biology weak link, 2022, Advanced Drug Delivery Reviews
  • Flipper Probes for the Community, 2021, CHIMIA International Journal for Chemistry
  • Calcium storage in multivesicular endo-lysosome, 2023, Physical Biology

Their research has appeared in several journals, including:

  • The Journal of Cell Biology
  • Nature Cell Biology
  • Advanced Drug Delivery Reviews
  • CHIMIA International Journal for Chemistry
  • Physical Biology

Collaborative efforts are notable in their career; frequent co-authors include Vincent Mercier, Aurélien Roux, Jorge Larios, Antoine Goujon, and Stefan Matile. These partnerships have contributed to multiple research projects and publications over time.

Jean Gruenberg has received recognition as a Member of the European Molecular Biology Organization (EMBO), reflecting a level of distinction within the molecular biology community.

Best Publications

  • rab5 controls early endosome fusion in vitro.

    Jean-Pierre Gorvel;Philippe Chavrier;Marino Zerial;Jean Gruenberg

  • Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

    Harald Alfred Stenmark;Robert G. Parton;Olivia Steele-Mortimer;Anne Lütcke

  • The endocytic pathway: a mosaic of domains

    Jean Gruenberg

  • The biogenesis of multivesicular endosomes

    Jean Gruenberg;Harald Stenmark

  • A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

    T Kobayashi;E Stang;K S Fang;P de Moerloose

  • Membrane transport in the endocytic pathway

    Jean Gruenberg;Frederick R Maxfield

  • Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization

    Hirotami Matsuo;Julien Chevallier;Nathalie Mayran;Isabelle Le Blanc

  • Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport

    Toshihide Kobayashi;Marie-Hélène Beuchat;Margaret Lindsay;Sonia Frias

  • Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitro.

    J Gruenberg;G Griffiths;K E Howell

  • Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest

    Rutilio A. Fratti;Jonathan M. Backer;Jean Gruenberg;Silvia Corvera

  • Cytoplasmic dynein-dependent vesicular transport from early to late endosomes.

    F Aniento;N Emans;G Griffiths;J Gruenberg

  • Hypervariable C-terminal domain of rab proteins acts as a targeting signal.

    Philippe Chavrier;Jean-Pierre Gorvel;Ernst Stelzer;Kai Simons

  • An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes.

    F Aniento;F Gu;R G Parton;J Gruenberg

  • Vacuolar ATPase activity is required for endosomal carrier vesicle formation.

    Michael J. Clague;Sylvie Urbé;Fernando Aniento;Jean Gruenberg

  • Membrane traffic in endocytosis: insights from cell-free assays.

    Jean Gruenberg;Kathryn E. Howell

  • Endosome maturation, transport and functions.

    Cameron C Scott;Fabrizio Vacca;Jean Gruenberg

  • Separation and Characterization of Late Endosomal Membrane Domains

    Toshihide Kobayashi;Toshihide Kobayashi;Marie-Hélène Beuchat;Julien Chevallier;Asami Makino

  • Mechanisms of pathogen entry through the endosomal compartments.

    Jean Gruenberg;F. Gisou van der Goot;F. Gisou van der Goot

  • Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase.

    Otilia V. Vieira;Cecilia Bucci;Rene E. Harrison;William S. Trimble

  • Late endosome motility depends on lipids via the small GTPase Rab7.

    Cécile Lebrand;Michela Corti;Holly Goodson;Holly Goodson;Pierre Cosson

Frequent Co-Authors

Robert G. Parton
Robert G. Parton University of Queensland
Toshihide Kobayashi
Toshihide Kobayashi University of Strasbourg
F. Gisou van der Goot
F. Gisou van der Goot École Polytechnique Fédérale de Lausanne
Kathryn E. Howell
Kathryn E. Howell University of Colorado Anschutz Medical Campus
Jean-Pierre Gorvel
Jean-Pierre Gorvel Aix-Marseille University
Gareth Griffiths
Gareth Griffiths University of Oslo
Kai Simons
Kai Simons Lipotype
Lucas Pelkmans
Lucas Pelkmans University of Zurich
Michael J. Clague
Michael J. Clague University of Liverpool
Stefan Matile
Stefan Matile University of Geneva

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