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Neuroscience

D-Index
36
Citations
4075
World Ranking
9078
National Ranking
504

Overview

Marcello Melone is affiliated with Marche Polytechnic University in Italy and conducts research primarily in the fields of Neuroscience and Medicine. Their work focuses on several subfields, including Cellular and Molecular Neuroscience, Molecular Biology, Pharmacology, Physiology, and Psychiatry and Mental Health.

The research topics covered by Melone include:

  • Neuroscience and Neuropharmacology Research
  • Cholinesterase and Neurodegenerative Diseases
  • Nicotinic Acetylcholine Receptors Study
  • Alzheimer's disease research and treatments
  • Migraine and Headache Studies
  • Photoreceptor and optogenetics research
  • Receptor Mechanisms and Signaling

Marcello Melone has published multiple papers in high-profile venues. Some recent works include:

  • "Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer's Disease," 2021, Progress in Neurobiology
  • "Non-canonical glutamate signaling in a genetic model of migraine with aura," 2020, Neuron
  • "Astrocytes mediate long-lasting synaptic regulation of ventral tegmental area dopamine neurons," 2022, Nature Neuroscience
  • "A Reappraisal of GAT-1 Localization in Neocortex," 2020, Frontiers in Cellular Neuroscience
  • "Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice," 2022, Molecular Neurodegeneration

Their frequent coauthors include:

  • Fiorenzo Conti
  • Maria Rosaria Tropea
  • Daniela Puzzo
  • Arianna Pugliese
  • Domenica Donatella Li Puma

Marcello Melone's research has been published repeatedly in these venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Progress in Neurobiology
  • Nature Neuroscience
  • Alzheimer s & Dementia
  • Neuron

Best Publications

  • GABA transporters in the mammalian cerebral cortex: localization, development and pathological implications.

    Fiorenzo Conti;Andrea Minelli;Marcello Melone

  • EAAC1, a high-affinity glutamate tranporter, is localized to astrocytes and gabaergic neurons besides pyramidal cells in the rat cerebral cortex.

    Fiorenzo Conti;Silvia DeBiasi;Andrea Minelli;Jeffrey D. Rothstein

  • Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortex

    Fiorenzo Conti;Marcello Melone;Silvia de Biasi;Andrea Minelli

  • Expression of NR1 and NR2A/B subunits of the NMDA receptor in cortical astrocytes.

    Fiorenzo Conti;Silvia DeBiasi;Andrea Minelli;Marcello Melone

  • Increased expression of the astrocytic glutamate transporter GLT-1 in the prefrontal cortex of schizophrenics

    Carlos Matute;Marcello Melone;Ainara Vallejo-Illarramendi;Fiorenzo Conti

  • Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2.

    Clizia Capuani;Marcello Melone;Angelita Tottene;Luca Bragina

  • Neuronal, glial, and epithelial localization of γ-aminobutyric acid transporter 2, a high-affinity γ-aminobutyric acid plasma membrane transporter, in the cerebral cortex and neighboring structures

    Fiorenzo Conti;Laura Vitellaro Zuccarello;Paolo Barbaresi;Andrea Minelli

  • Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes.

    Letizia Mariotti;Gabriele Losi;Gabriele Losi;Annamaria Lia;Annamaria Lia;Marcello Melone

  • Neuronal and Glial Localization of NR1 and NR2A/B Subunits of the NMDA Receptor in the Human Cerebral Cortex

    Fiorenzo Conti;Paolo Barbaresi;Marcello Melone;Alessandro Ducati

  • The expression of glutamate transporter GLT-1 in the rat cerebral cortex is down-regulated by the antipsychotic drug clozapine.

    M Melone;L Vitellaro-Zuccarello;A Vallejo-Illarramendi;A Pérez-Samartin

  • Neuronal and glial localization of NMDA receptors in the cerebral cortex

    Fiorenzo Conti;Andrea Minelli;Silvia DeBiasi;Marcello Melone

  • Presynaptic NMDA receptors in the neocortex are both auto- and heteroreceptors

    Silvia DeBiasi;Andrea Minelli;Marcello Melone;Fiorenzo Conti

  • Light microscopic identification and immunocytochemical characterization of glutamatergic synapses in brain sections

    Marcello Melone;Marcello Melone;Alain Burette;Richard J. Weinberg

  • Up-regulation of GLT-1 severely impairs LTD at mossy fibre--CA3 synapses.

    Azar Omrani;Marcello Melone;Michele Bellesi;Victoria Safiulina

  • Localization of the Glutamine Transporter SNAT1 in Rat Cerebral Cortex and Neighboring Structures, With a Note on its Localization in Human Cortex

    Marcello Melone;Fiorinta Quagliano;Paolo Barbaresi;Hélène Varoqui

  • Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer's Disease.

    Livia La Barbera;Francescangelo Vedele;Annalisa Nobili;Paraskevi Krashia

  • Neuromodulatory Action of Picomolar Extracellular Aβ42 Oligomers on Presynaptic and Postsynaptic Mechanisms Underlying Synaptic Function and Memory.

    Walter Gulisano;Marcello Melone;Cristian Ripoli;Maria Rosaria Tropea

  • Synaptic localization of GLT-1a in the rat somatic sensory cortex.

    Marcello Melone;Michele Bellesi;Fiorenzo Conti

  • The glutamine commute: lost in the tube?

    Fiorenzo Conti;Marcello Melone

  • Clozapine reduces GLT-1 expression and glutamate uptake in astrocyte cultures.

    Ainara Vallejo-Illarramendi;Mónica Torres-Ramos;Marcello Melone;Fiorenzo Conti

Frequent Co-Authors

Fiorenzo Conti
Fiorenzo Conti Marche Polytechnic University
Giambattista Bonanno
Giambattista Bonanno University of Genoa
Nicholas C. Brecha
Nicholas C. Brecha University of California, Los Angeles
Daniela Puzzo
Daniela Puzzo University of Catania
Ottavio Arancio
Ottavio Arancio Columbia University
Claudio Grassi
Claudio Grassi Catholic University of the Sacred Heart
Jeffrey D. Rothstein
Jeffrey D. Rothstein Johns Hopkins University
Fabio Benfenati
Fabio Benfenati Italian Institute of Technology
Giorgio Carmignoto
Giorgio Carmignoto National Research Council (CNR)
Giorgio Casari
Giorgio Casari Vita-Salute San Raffaele University

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