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Neuroscience

D-Index
35
Citations
5365
World Ranking
9178
National Ranking
676

Overview

John Grist is affiliated with King's College London in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience, including subfields such as Molecular Biology and Cellular and Molecular Neuroscience.

The main topics covered in their research include:

  • Retinoids in leukemia and cellular processes
  • Nerve injury and regeneration
  • RNA Interference and Gene Delivery

John Grist has contributed to research published in the journal Frontiers in Molecular Neuroscience. One of their recent papers is titled "C286, an orally available retinoic acid receptor β agonist drug, regulates multiple pathways to achieve spinal cord injury repair," published in 2024 in Frontiers in Molecular Neuroscience.

Frequent collaborators in their research include:

  • Maria B. Goncalves
  • Yue Wu
  • Earl E. Clarke
  • Julien Moehlin
  • Marco Antonio Mendoza-Parra

The research contributions of John Grist demonstrate a focus on molecular mechanisms underlying nerve injury and regeneration, as well as cellular processes involving retinoids. Their work in RNA interference and gene delivery also indicates an engagement with techniques to modulate gene expression relevant to these topics.

Best Publications

  • Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain

    Anna K. Clark;Ping K. Yip;John Grist;Clive Gentry

  • Chondroitinase ABC Promotes Sprouting of Intact and Injured Spinal Systems after Spinal Cord Injury

    AW Barritt;M Davies;F Marchand;R Hartley

  • CCL2 is a key mediator of microglia activation in neuropathic pain states.

    Michael A. Thacker;Michael A. Thacker;Anna K. Clark;Thomas Bishop;John Grist

  • Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma.

    Raffaele Simeoli;Karli Montague;Hefin R. Jones;Laura Castaldi

  • Neuregulin-ErbB Signaling Promotes Microglial Proliferation and Chemotaxis Contributing to Microgliosis and Pain after Peripheral Nerve Injury

    Margarita Calvo;Ning Zhu;Christoforos Tsantoulas;Zhenzhong Ma

  • Gabapentin reverses microglial activation in the spinal cord of streptozotocin‐induced diabetic rats

    Rachel Wodarski;Anna K. Clark;John Grist;Fabien Marchand

  • Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions.

    Sophie Pezet;Fabien Marchand;Richard D'Mello;John Grist

  • Effects of Etanercept and Minocycline in a rat model of spinal cord injury

    Fabien Marchand;Christoforos Tsantoulas;Dalbinder Singh;John Grist

  • Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain

    Elizabeth A. Old;Suchita Nadkarni;John Grist;Clive Gentry

  • HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain

    Franziska Denk;Wenlong Huang;Ben Sidders;Angela Bithell

  • Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord.

    Liang-Fong Wong;Ping K Yip;Anna Battaglia;John Grist

  • Release of BDNF and GABA in the dorsal horn of neuropathic rats.

    Isobel Lever;Joanna Cunningham;John Grist;Ping K. Yip

  • EphB receptors and ephrin-B ligands regulate spinal sensory connectivity and modulate pain processing.

    Anna Aurora Battaglia;Karina Sehayek;John Grist;Stephen B McMahon

  • Conduction failure following spinal cord injury: functional and anatomical changes from acute to chronic stages

    Nicholas D. James;Katalin Bartus;John Grist;David L. H. Bennett

  • Following nerve injury neuregulin-1 drives microglial proliferation and neuropathic pain via the MEK/ERK pathway.

    Margarita Calvo;Ning Zhu;John Grist;Zhenzhong Ma

  • Sensory Neuron Downregulation of the Kv9.1 Potassium Channel Subunit Mediates Neuropathic Pain following Nerve Injury

    Christoforos Tsantoulas;Lan Zhu;Yasin Shaifta;John Grist

  • Neuronal RARβ Signaling Modulates PTEN Activity Directly in Neurons and via Exosome Transfer in Astrocytes to Prevent Glial Scar Formation and Induce Spinal Cord Regeneration

    Maria B. Goncalves;Tony Malmqvist;Earl Clarke;Chantal J. Hubens

  • BDNF modulates sensory neuron synaptic activity by a facilitation of GABA transmission in the dorsal horn.

    Sophie Pezet;Joanna Cunningham;Jaykumar Patel;John Grist

  • Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model

    Anna K. Clark;John Grist;Adam Al-Kashi;Mauro Perretti

  • Neuron-immune mechanisms contribute to pain in early stages of arthritis

    Francisco R. Nieto;Anna K. Clark;John Grist;Gareth J. Hathway

Frequent Co-Authors

Stephen B. McMahon
Stephen B. McMahon King's College London
Marzia Malcangio
Marzia Malcangio King's College London
Ping K. Yip
Ping K. Yip Queen Mary University of London
David L.H. Bennett
David L.H. Bennett University of Oxford
Elizabeth J. Bradbury
Elizabeth J. Bradbury King's College London
Jeffrey A. Loeb
Jeffrey A. Loeb University of Illinois at Chicago
Clive Gentry
Clive Gentry King's College London
Stuart Bevan
Stuart Bevan King's College London
Victoria Chapman
Victoria Chapman University of Nottingham
Antony M. Carr
Antony M. Carr University of Sussex

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