Koichi Obata

Overview

Best Publications

• Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with aδ/c‐fibers and colocalization with trk receptors

  Kimiko Kobayashi;Tetsuo Fukuoka;Koichi Obata;Hiroki Yamanaka

  1094
  Citations

• TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury

  Koichi Obata;Hirokazu Katsura;Toshiyuki Mizushima;Hiroki Yamanaka

  871
  Citations

• Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain

  Yi Dai;Shenglan Wang;Makoto Tominaga;Satoshi Yamamoto

  597
  Citations

• MAPK activation in nociceptive neurons and pain hypersensitivity

  Koichi Obata;Koichi Noguchi

  492
  Citations

• Role of Mitogen-Activated Protein Kinase Activation in Injured and Intact Primary Afferent Neurons for Mechanical and Heat Hypersensitivity after Spinal Nerve Ligation

  Koichi Obata;Hiroki Yamanaka;Kimiko Kobayashi;Yi Dai

  434
  Citations

• P2Y12 Receptor Upregulation in Activated Microglia Is a Gateway of p38 Signaling and Neuropathic Pain

  Kimiko Kobayashi;Hiroki Yamanaka;Tetsuo Fukuoka;Yi Dai

  379
  Citations

• Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain.

  Shenglan Wang;Yi Dai;Tetsuo Fukuoka;Hiroki Yamanaka

  372
  Citations

• Interleukin-18-Mediated Microglia/Astrocyte Interaction in the Spinal Cord Enhances Neuropathic Pain Processing after Nerve Injury

  Kan Miyoshi;Koichi Obata;Takashi Kondo;Haruki Okamura

  360
  Citations

• Contribution of injured and uninjured dorsal root ganglion neurons to pain behavior and the changes in gene expression following chronic constriction injury of the sciatic nerve in rats.

  Koichi Obata;Hiroki Yamanaka;Tetsuo Fukuoka;Dai Yi

  343
  Citations

• Differential Activation of Extracellular Signal-Regulated Protein Kinase in Primary Afferent Neurons Regulates Brain-Derived Neurotrophic Factor Expression after Peripheral Inflammation and Nerve Injury

  Koichi Obata;Hiroki Yamanaka;Yi Dai;Toshiya Tachibana

  331
  Citations

• BDNF in sensory neurons and chronic pain.

  Koichi Obata;Koichi Noguchi

  312
  Citations

• Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats.

  Hirokazu Katsura;Koichi Obata;Toshiyuki Mizushima;Hiroki Yamanaka

  300
  Citations

• Comparative study of the distribution of the α‐subunits of voltage‐gated sodium channels in normal and axotomized rat dorsal root ganglion neurons

  Tetsuo Fukuoka;Kimiko Kobayashi;Hiroki Yamanaka;Koichi Obata

  207
  Citations

• Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord

  Kimiko Kobayashi;Tetsuo Fukuoka;Hiroki Yamanaka;Yi Dai

  200
  Citations

• Activation of Src-Family Kinases in Spinal Microglia Contributes to Mechanical Hypersensitivity after Nerve Injury

  Hirokazu Katsura;Koichi Obata;Toshiyuki Mizushima;Jun Sakurai

  199
  Citations

• Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats.

  Koichi Obata;Hiroki Yamanaka;Yi Dai;Toshiyuki Mizushima

  198
  Citations

• Expression of neurotrophic factors in the dorsal root ganglion in a rat model of lumbar disc herniation

  Koichi Obata;Hiroaki Tsujino;Hiroki Yamanaka;Dai Yi

  189
  Citations

• Differential expression patterns of mRNAs for P2X receptor subunits in neurochemically characterized dorsal root ganglion neurons in the rat

  Kimiko Kobayashi;Tetsuo Fukuoka;Hiroki Yamanaka;Yi Dai

  174
  Citations

• The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint.

  Daisuke Seino;Atsushi Tokunaga;Toshiya Tachibana;Shinichi Yoshiya

  126
  Citations

• Activation of p38 MAPK in primary afferent neurons by noxious stimulation and its involvement in the development of thermal hyperalgesia.

  Toshiyuki Mizushima;Koichi Obata;Hiroki Yamanaka;Yi Dai

  124
  Citations

• Activation of extracellular signal-regulated protein kinase in the dorsal root ganglion following inflammation near the nerve cell body.

  K Obata;H Yamanaka;Y Dai;T Mizushima

  122
  Citations