World's Best Scientists 2026 revealed!
Hidetoshi Tozaki-Saitoh

Hidetoshi Tozaki-Saitoh

D-Index & Metrics

Neuroscience

D-Index
45
Citations
7101
World Ranking
6954
National Ranking
233

Hidetoshi Tozaki-Saitoh publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Hidetoshi Tozaki-Saitoh sits on this spectrum.

38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientists 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38 publications 887+

This scientist: 90 publications — 12th percentile

12% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

Hidetoshi Tozaki-Saitoh D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Hidetoshi Tozaki-Saitoh sits on this spectrum.

30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30 D-Index 163+

This scientist: 45 D-Index — 29th percentile

29% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

Overview

Hidetoshi Tozaki-Saitoh is affiliated with Kyushu University in Japan and has an extensive publication record primarily in the fields of medicine and neuroscience. Their research focuses notably on pain mechanisms, neuroinflammation, ion channel regulation, and purinergic signaling.

The main fields of study covered by Tozaki-Saitoh include:

  • Medicine
  • Neuroscience

They have contributed to various subfields such as:

  • Physiology
  • Neurology
  • Immunology
  • Molecular Biology
  • Cellular and Molecular Neuroscience

Key research topics addressed by Tozaki-Saitoh encompass:

  • Pain Mechanisms and Treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Ion channel regulation and function
  • Adenosine and Purinergic Signaling
  • Immune Response and Inflammation
  • Exercise and Physiological Responses
  • Neuropeptides and Animal Physiology

The scientist has several recent publications with notable research findings, including:

  • "Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity," 2020, Nature Neuroscience
  • "A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior," 2021, Proceedings of the National Academy of Sciences
  • "Mechanical pain of the lower extremity after compression of the upper spinal cord involves signal transducer and activator of transcription 3-dependent reactive astrocytes and interleukin-6," 2020, Brain Behavior and Immunity
  • "The Role of Microglial Purinergic Receptors in Pain Signaling," 2022, Molecules
  • "Involvement of exchange protein directly activated by cAMP and tumor progression locus 2 in IL-1β production in microglial cells following activation of β-adrenergic receptors," 2020, Journal of Pharmacological Sciences

Frequent co-authors who have collaborated with Tozaki-Saitoh include:

  • Makoto Tsuda
  • K. Koga
  • Ryoichi Tashima
  • Kazuhide Inoue
  • Sachi Shimizu

The scientist's work has been published in venues such as:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Cells
  • Preprints.org
  • Nature Neuroscience
  • Proceedings of the National Academy of Sciences

Best Publications

  • IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

    Takahiro Masuda;Makoto Tsuda;Ryohei Yoshinaga;Hidetoshi Tozaki-Saitoh

  • JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats

    Makoto Tsuda;Yuta Kohro;Takayuki Yano;Tomoko Tsujikawa

  • P2Y12 Receptors in Spinal Microglia Are Required for Neuropathic Pain after Peripheral Nerve Injury

    Hidetoshi Tozaki-Saitoh;Makoto Tsuda;Hiroyuki Miyata;Kazuaki Ueda

  • IFN-γ receptor signaling mediates spinal microglia activation driving neuropathic pain

    Makoto Tsuda;Takahiro Masuda;Junko Kitano;Hiroshi Shimoyama

  • STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch

    Miho Shiratori-Hayashi;Keisuke Koga;Hidetoshi Tozaki-Saitoh;Yuta Kohro

  • Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain.

    Takahiro Masuda;Shosuke Iwamoto;Ryohei Yoshinaga;Hidetoshi Tozaki-Saitoh

  • Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays

    Makoto Tsuda;Kazuya Kuboyama;Tomoyuki Inoue;Kenichiro Nagata

  • P2Y6 receptor-Gα12/13 signalling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis

    Motohiro Nishida;Yoji Sato;Aya Uemura;Yusuke Narita

  • Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex

    Tao Chen;Wataru Taniguchi;Qi Yu Chen;Hidetoshi Tozaki-Saitoh

  • Activation of dorsal horn microglia contributes to diabetes‐induced tactile allodynia via extracellular signal‐regulated protein kinase signaling

    Makoto Tsuda;Hikaru Ueno;Ayako Kataoka;Hidetoshi Tozaki-Saitoh

  • P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways.

    Miho Shiratori;Hidetoshi Tozaki-Saitoh;Mai Yoshitake;Makoto Tsuda

  • Neuronal CCL21 up‐regulates microglia P2X4 expression and initiates neuropathic pain development

    Knut Biber;Knut Biber;Makoto Tsuda;Hidetoshi Tozaki-Saitoh;Keiko Tsukamoto

  • Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain

    Takahiro Masuda;Yui Ozono;Satsuki Mikuriya;Yuta Kohro

  • The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S

    Yoshinori Hayashi;Satoru Koyanagi;Naoki Kusunose;Ryo Okada

  • Antidepressants inhibit P2X4 receptor function: a possible involvement in neuropathic pain relief

    Kenichiro Nagata;Toshiyasu Imai;Tomohiro Yamashita;Makoto Tsuda

  • Pain and purinergic signaling

    Makoto Tsuda;Hidetoshi Tozaki-Saitoh;Kazuhide Inoue

  • P2X4 receptors and neuropathic pain

    Makoto Tsuda;Takahiro Masuda;Hidetoshi Tozaki-Saitoh;Kazuhide Inoue

  • P2Y1 receptor signaling enhances neuroprotection by astrocytes against oxidative stress via IL‐6 release in hippocampal cultures

    Takumi Fujita;Hidetoshi Tozaki-Saitoh;Kazuhide Inoue

  • Microglial regulation of neuropathic pain.

    Makoto Tsuda;Takahiro Masuda;Hidetoshi Tozaki-Saitoh;Kazuhide Inoue

  • A novel P2X4 receptor-selective antagonist produces anti-allodynic effect in a mouse model of herpetic pain

    Yuta Matsumura;Tomohiro Yamashita;Atsushi Sasaki;Eriko Nakata

  • Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT

    Ayako Kataoka;Hidetoshi Tozaki-Saitoh;Yui Koga;Makoto Tsuda

Frequent Co-Authors

Makoto Tsuda
Makoto Tsuda Kyushu University
Kazuhide Inoue
Kazuhide Inoue Kyushu University
Hidemasa Furue
Hidemasa Furue Hyogo College of Medicine
Tomohiko Tamura
Tomohiko Tamura Yokohama City University
Shinichi Kohsaka
Shinichi Kohsaka Keio University
Schuichi Koizumi
Schuichi Koizumi University of Yamanashi
Hendrikus W. G. M. Boddeke
Hendrikus W. G. M. Boddeke University Medical Center Groningen
Motohiro Nishida
Motohiro Nishida Kyushu University
Michael W. Salter
Michael W. Salter University of Toronto
Min Zhuo
Min Zhuo University of Toronto

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