World's Best Scientists 2026 revealed!
Christa E. Müller

Christa E. Müller

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Chemistry
Germany
2026

D-Index & Metrics

Chemistry

D-Index
99
Citations
30988
World Ranking
1357
National Ranking
104

Research.com Recognitions

  • 2026 - Research.com Chemistry in Germany Leader Award
  • 2025 - Research.com Chemistry in Germany Leader Award
  • 2022 - Research.com Chemistry in Germany Leader Award

Overview

Christa E. Müller is affiliated with the University of Bonn in Germany. Their research primarily focuses on biochemical, genetic, and molecular biology disciplines, with significant contributions also in medicine. Their work bridges fundamental molecular mechanisms and applied biomedical sciences.

Müller's research interests are concentrated in several main topics including:

  • Adenosine and Purinergic Signaling
  • Receptor Mechanisms and Signaling
  • Pharmacological Receptor Mechanisms and Effects
  • Neuropeptides and Animal Physiology
  • Computational Drug Discovery Methods
  • Click Chemistry and Applications
  • SARS-CoV-2 and COVID-19 Research

Their scientific contributions span subfields such as molecular biology, physiology, organic chemistry, cellular and molecular neuroscience, and materials chemistry, reflecting a multidisciplinary approach to molecular and cellular processes.

Some of Müller's recent notable publications include:

  • "Update of P2X receptor properties and their pharmacology: IUPHAR Review 30" (2020), published in British Journal of Pharmacology
  • "Update of P2Y receptor pharmacology: IUPHAR Review 27" (2020), published in British Journal of Pharmacology
  • "Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors" (2021), published in Angewandte Chemie International Edition
  • "Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine" (2022), published in Nature
  • "International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update" (2022), published in Pharmacological Reviews

Throughout their career, Müller has published extensively in several key scientific journals. The most frequent venues for their publications include:

  • Journal of Medicinal Chemistry
  • ACS Pharmacology & Translational Science
  • The Cambridge Structural Database
  • International Journal of Molecular Sciences
  • ACS Medicinal Chemistry Letters

The scientist collaborates regularly with several co-authors, indicating an active engagement in collaborative research projects. Frequent co-authors include:

  • Vigneshwaran Namasivayam
  • Michael Gütschow
  • Katharina Sylvester
  • Jan Voss
  • Craig W. Lindsley

Best Publications

  • International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update

    Bertil B. Fredholm;Adriaan P. IJzerman;Kenneth A. Jacobson;Joel Linden

  • Recent developments in adenosine receptor ligands and their potential as novel drugs

    Christa E. Müller;Kenneth A. Jacobson

  • Structure of the human P2Y12 receptor in complex with an antithrombotic drug

    Kaihua Zhang;Jin Zhang;Zhan-Guo Gao;Dandan Zhang

  • Anthraquinones As Pharmacological Tools and Drugs

    Enas M. Malik;Christa E. Müller

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

    Stephen P.H. Alexander;Arthur Christopoulos;Anthony P. Davenport;Eamonn Kelly

  • Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors.

    Thorsten Gnad;Saskia Scheibler;Ivar von Kügelgen;Camilla Scheele

  • Agonist-bound structure of the human P2Y12 receptor

    Jin Zhang;Kaihua Zhang;Zhan-Guo Gao;Silvia Paoletta

  • The experimental power of FR900359 to study Gq-regulated biological processes

    Ramona Schrage;Anna Lena Schmitz;Evelyn Gaffal;Suvi Annala

  • Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress

    Manuella P. Kaster;Manuella P. Kaster;Nuno J. Machado;Henrique B. Silva;Ana Nunes

  • Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids.

    Paulina Carriba;Oskar Ortiz;Kshitij Patkar;Zuzana Justinova;Zuzana Justinova

  • CD39/ENTPD1 Expression by CD4+Foxp3+ Regulatory T Cells Promotes Hepatic Metastatic Tumor Growth in Mice

    Xiaofeng Sun;Yan Wu;Wenda Gao;Keiichi Enjyoji

  • Medicinal chemistry of adenosine, P2Y and P2X receptors.

    Kenneth A. Jacobson;Christa E. Müller

  • Update of P2X receptor properties and their pharmacology: IUPHAR Review 30

    Peter Illes;Peter Illes;Christa E. Müller;Kenneth A. Jacobson;Thomas Grutter

  • CD39/Ectonucleoside Triphosphate Diphosphohydrolase 1 Provides Myocardial Protection During Cardiac Ischemia/Reperfusion Injury

    David Köhler;Tobias Eckle;Marion Faigle;Almut Grenz

  • Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences

    Patrick A. Randall;Marta Pardo;Marta Pardo;Eric J. Nunes;Laura López Cruz;Laura López Cruz

  • Prodrug approaches for enhancing the bioavailability of drugs with low solubility.

    Christa E. Müller

  • Structure–activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP)

    Anne Pick;Henrik Müller;Ralf Mayer;Britta Haenisch

  • Lignans Isolated from Valerian: Identification and Characterization of a New Olivil Derivative with Partial Agonistic Activity at A1 Adenosine Receptors

    Britta Schumacher;Silke Scholle;Josef Hölzl;Nasser Khudeir

  • Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.

    Marzena Karcz-Kubicha;Katerina Antoniou;Anton Terasmaa;Davide Quarta

  • Crystal Structure of the Human Ecto-5′-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling

    Karen Knapp;Matthias Zebisch;Matthias Zebisch;Jan Pippel;Ali El-Tayeb

  • Update of P2Y receptor pharmacology: IUPHAR Review 27.

    Kenneth A Jacobson;Esmerilda G Delicado;Christian Gachet;Charles Kennedy

  • Multigram-Scale Syntheses, Stability, and Photoreactions of A2A Adenosine Receptor Antagonists with 8-Styrylxanthine Structure: Potential Drugs for Parkinson's Disease

    Jörg Hockemeyer;Joachim C Burbiel;Christa E Müller

Frequent Co-Authors

Mercè Correa
Mercè Correa Jaume I University
Kenneth A. Jacobson
Kenneth A. Jacobson National Institutes of Health
John D. Salamone
John D. Salamone University of Connecticut
Herbert Zimmermann
Herbert Zimmermann Goethe University Frankfurt
Rafael Franco
Rafael Franco University of Barcelona
Gabriele M. König
Gabriele M. König University of Bonn
Sergi Ferré
Sergi Ferré National Institute on Drug Abuse
Evi Kostenis
Evi Kostenis University of Bonn
Jean Sévigny
Jean Sévigny Université Laval
Michael Gütschow
Michael Gütschow University of Bonn

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