World's Best Scientists 2026 revealed!
Serge Rivest

Serge Rivest

D-Index & Metrics

Biology and Biochemistry

D-Index
107
Citations
37937
World Ranking
1113
National Ranking
26

Medicine

D-Index
107
Citations
38050
World Ranking
6308
National Ranking
249

Overview

Serge Rivest is affiliated with Université Laval in Canada and focuses primarily on research areas spanning neuroscience and medicine, with a strong emphasis on neuroinflammation and neurodegeneration mechanisms. Their work encompasses a range of interconnected fields and topics, contributing to the understanding of neurological diseases, particularly Alzheimer's disease.

Their main fields of study include:

  • Neuroscience
  • Medicine

Within these fields, they specialize in several subfields, such as:

  • Neurology
  • Immunology
  • Physiology
  • Molecular Biology
  • Biological Psychiatry

This scientist's research topics highlight specific areas of investigation, including:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Immune cells in cancer
  • Tryptophan and brain disorders
  • Immune Response and Inflammation
  • Circadian rhythm and melatonin
  • Multiple Sclerosis Research Studies

Serge Rivest has collaborated frequently with several co-authors, including:

  • Vincent Pons
  • Nataly Laflamme
  • Paul Préfontaine
  • Majid Ghareghani
  • Baiba Lāce

Their recent publications span important journals and venues, reflecting ongoing contributions to the biomedical research community. Some notable recent papers are:

  • "Alzheimer's disease: microglia targets and their modulation to promote amyloid phagocytosis and mitigate neuroinflammation," 2020, Expert Opinion on Therapeutic Targets
  • "Microglia Purinoceptor P2Y6: An Emerging Therapeutic Target in CNS Diseases," 2020, Cells
  • "Conditional genetic deletion of CSF1 receptor in microglia ameliorates the physiopathology of Alzheimer's disease," 2021, Alzheimer's Research & Therapy
  • "Targeting innate immunity to protect and cure Alzheimer's disease: opportunities and pitfalls," 2021, Molecular Psychiatry
  • "Targeting Systemic Innate Immune Cells as a Therapeutic Avenue for Alzheimer Disease," 2022, Pharmacological Reviews

The publications of Serge Rivest have appeared multiple times in frequently used venues such as:

  • Cells
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Neurotherapeutics

This comprehensive body of work highlights ongoing research into the immune components of neurological diseases and the mechanisms involved in neurodegeneration and inflammation. Their collaborations and publications indicate a continuing focus on elucidating pathways that could lead to therapeutic advances in conditions such as Alzheimer's disease.

Best Publications

  • Bone Marrow-Derived Microglia Play a Critical Role in Restricting Senile Plaque Formation in Alzheimer's Disease

    Alain R. Simard;Denis Soulet;Genevieve Gowing;Jean Pierre Julien

  • Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

    Arthur Liesz;Elisabeth Suri-Payer;Claudia Veltkamp;Henrike Doerr

  • Effect of stress on the activity of the hypothalamic-pituitary-gonadal axis: peripheral and central mechanisms.

    Catherine Rivier;Serge Rivest

  • Regulation of innate immune responses in the brain.

    Serge Rivest

  • Innate immunity: the missing link in neuroprotection and neurodegeneration?

    Minh Dang Nguyen;Jean-Pierre Julien;Serge Rivest

  • Expression and neuropeptidergic characterization of estrogen receptors (ERalpha and ERbeta) throughout the rat brain: anatomical evidence of distinct roles of each subtype.

    Nathalie Laflamme;Rossella E. Nappi;Guy Drolet;Claude Labrie

  • Toll-like Receptor 4: The Missing Link of the Cerebral Innate Immune Response Triggered by Circulating Gram-Negative Bacterial Cell Wall Components

    Nathalie Laflamme;Serge Rivest

  • Inefficient clearance of myelin debris by microglia impairs remyelinating processes

    Antoine Lampron;Antoine Larochelle;Nathalie Laflamme;Paul Préfontaine

  • Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior

    Mary P. Stenzel-Poore;Stephen C. Heinrichs;Serge Rivest;George F. Koob

  • Chemokine Expression by Glial Cells Directs Leukocytes to Sites of Axonal Injury in the CNS

    Alicia A. Babcock;William A. Kuziel;Serge Rivest;Trevor Owens

  • Molecular insights on the cerebral innate immune system.

    Serge Rivest

  • Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain.

    Ji Zhang;Xiang Qun Shi;Stefania Echeverry;Jeffrey S. Mogil

  • Regulation of the Genes Encoding Interleukin‐6, Its Receptor, and gp130 in the Rat Brain in Response to the Immune Activator Lipopolysaccharide and the Proinflammatory Cytokine Interleukin‐1β

    Luc Vallières;Serge Rivest

  • Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia.

    Alain R. Simard;Serge Rivest

  • The HPA – Immune Axis and the Immunomodulatory Actions of Glucocorticoids in the Brain

    Marc-Andre Bellavance;Serge Rivest

  • Neuroprotective role of the innate immune system by microglia.

    I. Glezer;A.R. Simard;S. Rivest

  • The LPS receptor (CD14) links innate immunity with Alzheimer's disease.

    K. Fassbender;S. Walter;S. Kühl;S. Kühl;R. Landmann

  • An Essential Role of Interleukin-1β in Mediating NF-κB Activity and COX-2 Transcription in Cells of the Blood–Brain Barrier in Response to a Systemic and Localized Inflammation But Not During Endotoxemia

    Nathalie Laflamme;Steve Lacroix;Serge Rivest

  • Effects of circulating tumor necrosis factor on the neuronal activity and expression of the genes encoding the tumor necrosis factor receptors (p55 and p75) in the rat brain: a view from the blood-brain barrier.

    S Nadeau;S Rivest

  • How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli.

    Serge Rivest;Steve Lacroix;Luc Vallières;Sylvain Nadeau

Frequent Co-Authors

V. Wee Yong
V. Wee Yong University of Calgary
Denis Richard
Denis Richard Université Laval
Guy Boivin
Guy Boivin Université Laval
Marie-Ève Tremblay
Marie-Ève Tremblay University of Victoria
Guy Drolet
Guy Drolet Université Laval
Martin Olivier
Martin Olivier McGill University
Regine Landmann
Regine Landmann University Hospital of Basel
Marcelo Gottschalk
Marcelo Gottschalk University of Montreal
Peter K. Stys
Peter K. Stys University of Calgary
Katherine A. Siminovitch
Katherine A. Siminovitch Lunenfeld-Tanenbaum Research Institute

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