World's Best Scientists 2026 revealed!
Roderick E. Hubbard

Roderick E. Hubbard

D-Index & Metrics

Chemistry

D-Index
64
Citations
23980
World Ranking
7907
National Ranking
454

Biology and Biochemistry

D-Index
64
Citations
24471
World Ranking
9455
National Ranking
720

Overview

Roderick E. Hubbard is affiliated with the University of York in the United Kingdom. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology as the leading subfield. Additional areas of involvement include Materials Chemistry, Computational Theory and Mathematics, Organic Chemistry, and Pharmacology.

The scientist's work covers a variety of topics related to chemical and biological sciences. Key topics are:

  • Computational Drug Discovery Methods
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Chemical Synthesis and Analysis
  • Microbial Natural Products and Biosynthesis
  • Receptor Mechanisms and Signaling
  • Ubiquitin and proteasome pathways

Roderick E. Hubbard has contributed to several recent publications, often collaborating with other researchers. Selected recent papers include:

  • "Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor," 2020, Journal of Medicinal Chemistry
  • "Design and Synthesis of 56 Shape-Diverse 3D Fragments," 2020, Chemistry - A European Journal
  • "Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B," 2021, Journal of Medicinal Chemistry
  • "Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V," 2020, ACS Catalysis
  • "Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors," 2021, Journal of Medicinal Chemistry

The scientist's frequent collaborators include Stephen D. Roughley, Peter O'Brien, Hanna F. Klein, James D. Firth, and James B. Murray.

Publications by Roderick E. Hubbard often appear in specific venues that reflect their research focus. Frequent publication outlets are:

  • The Cambridge Structural Database
  • Journal of Medicinal Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • RSC Medicinal Chemistry
  • Biomolecular NMR Assignments

Best Publications

  • Molecular basis of agonism and antagonism in the oestrogen receptor.

    Andrzej M. Brzozowski;Ashley C. W. Pike;Zbigniew Dauter;Roderick E. Hubbard

  • Hydrogen bonding in globular proteins

    E.N. Baker;R.E. Hubbard

  • Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport.

    Stephen C. Hyde;Paul Emsley;Michael J. Hartshorn;Michael M. Mimmack

  • Structure of the Ligand-Binding Domain of Oestrogen Receptor Beta in the Presence of a Partial Agonist and a Full Antagonist

    Ashley C.W. Pike;Andrzej M. Brzozowski;Roderick E. Hubbard;Tomas Bonn

  • Twenty years on: the impact of fragments on drug discovery.

    Daniel A. Erlanson;Stephen W. Fesik;Roderick E. Hubbard;Wolfgang Jahnke

  • The structure of 2Zn pig insulin crystals at 1.5 A resolution.

    Edward N. Baker;Thomas L. Blundell;John F. Cutfield;Susan M. Cutfield

  • Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses.

    Gabriele S. V. Kuschert;Florence Coulin;Christine A. Power;Amanda E. I. Proudfoot

  • rDock: A Fast, Versatile and Open Source Program for Docking Ligands to Proteins and Nucleic Acids

    Sergio Ruiz-Carmona;Daniel Alvarez-Garcia;Nicolas Foloppe;A. Beatriz Garmendia-Doval

  • NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

    Suzanne A Eccles;Andy Massey;Florence I Raynaud;Swee Y Sharp

  • 4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

    Paul A. Brough;Wynne Aherne;Xavier Barril;Jenifer Borgognoni

  • Hydrogen Bonds in Proteins: Role and Strength

    Roderick E Hubbard;Muhammad Kamran Haider

  • Structural insights into the mode of action of a pure antiestrogen.

    Ashley C.W. Pike;A. Marek Brzozowski;Julia Walton;Roderick E. Hubbard

  • Biophysics in drug discovery: impact, challenges and opportunities

    Jean-Paul Renaud;Chun-wa Chung;U. Helena Danielson;Ursula Egner

  • Heat-stable antifreeze protein from grass

    Chris Sidebottom;Sarah Buckley;Paul Pudney;Sarah Twigg

  • Structure-Activity Relationships in Purine-Based Inhibitor Binding to Hsp90 Isoforms

    Lisa Wright;Xavier Barril;Brian Dymock;Louisa Sheridan

  • HOOK: a program for finding novel molecular architectures that satisfy the chemical and steric requirements of a macromolecule binding site.

    Michael B. Eisen;Don C. Wiley;Don C. Wiley;Martin Karplus;Roderick E. Hubbard

  • Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design.

    Brian W Dymock;Xavier Barril;Paul A Brough;Julie E Cansfield

  • Towards predictive ligand design with free-energy based computational methods?

    Foloppe N;Hubbard R

  • Identification of a glycosaminoglycan binding surface on human interleukin-8.

    Gabriele S. V. Kuschert;Arlene J. Hoogewerf;Amanda E. I. Proudfoot;Chun-wa Chung

  • A structural biologist's view of the oestrogen receptor

    Ashley C.W Pike;Andrzej M Brzozowski;Roderick E Hubbard

Frequent Co-Authors

Xavier Barril
Xavier Barril University of Barcelona
Jan-Åke Gustafsson
Jan-Åke Gustafsson University of Houston
Peter O'Brien
Peter O'Brien University of York
Pawel Herzyk
Pawel Herzyk University of Glasgow
Gideon J. Davies
Gideon J. Davies University of York
Paul Workman
Paul Workman Institute of Cancer Research
Chandra S. Verma
Chandra S. Verma Agency for Science, Technology and Research
Florence I. Raynaud
Florence I. Raynaud Institute of Cancer Research
Guy Dodson
Guy Dodson University of York
Chrisostomos Prodromou
Chrisostomos Prodromou University of Sussex

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in Chemistry and its real-world applications, exploring related fields can open diverse career pathways. One such option is pursuing a master's in forensic psychology online. This degree blends scientific knowledge with criminal investigations, providing opportunities in law enforcement and legal settings.

Careers in forensic science are another promising path for chemistry graduates. These roles often require a strong foundation in chemical analysis to assist in crime scene investigations. Learning more about careers in forensic science can help clarify the skills and education needed for success in this field.

When considering online education options, understanding how much does a criminal justice degree cost is essential. This helps prospective students plan financially for their studies.

For those seeking quicker entry into the workforce, a 2 year criminal justice degree online offers an efficient option to gain relevant knowledge and skills.

Best Scientists Citing Roderick E. Hubbard

Trending Scientists

Recently Published Articles