D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 109 Citations 43,738 642 World Ranking 463 National Ranking 224
Medicine D-index 100 Citations 37,365 496 World Ranking 4916 National Ranking 2749

Research.com Recognitions

Awards & Achievements

1974 - Fellow of Alfred P. Sloan Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Organic chemistry
  • Gene

His primary areas of study are Estrogen receptor, Internal medicine, Estrogen receptor alpha, Endocrinology and Stereochemistry. His Estrogen receptor research includes elements of Agonist, Receptor, Biochemistry and Estrogen. The various areas that John A. Katzenellenbogen examines in his Internal medicine study include Standardized uptake value and Oncology.

His Estrogen receptor alpha research incorporates elements of Coactivator, Signal transduction, Regulation of gene expression, Diarylpropionitrile and In vivo. His studies deal with areas such as Inflammation, Nuclear receptor, Androgen receptor and Cell biology as well as Endocrinology. His Stereochemistry study integrates concerns from other disciplines, such as Alkylation, Ligand, Ring, Chemical synthesis and Binding site.

His most cited work include:

  • Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture (1074 citations)
  • Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity. (1057 citations)
  • Pyrazole Ligands: Structure−Affinity/Activity Relationships and Estrogen Receptor-α-Selective Agonists (654 citations)

What are the main themes of his work throughout his whole career to date?

Estrogen receptor, Stereochemistry, Internal medicine, Estrogen and Endocrinology are his primary areas of study. John A. Katzenellenbogen has researched Estrogen receptor in several fields, including Receptor, Biochemistry and Ligand. His Receptor research includes themes of Steroid and Progesterone receptor.

His study in Stereochemistry is interdisciplinary in nature, drawing from both Agonist, Structure–activity relationship, Chemical synthesis and Binding site. His Estrogen research is multidisciplinary, incorporating elements of Antiestrogen and Tamoxifen. As part of one scientific family, John A. Katzenellenbogen deals mainly with the area of Endocrinology, narrowing it down to issues related to the In vivo, and often In vitro.

He most often published in these fields:

  • Estrogen receptor (47.33%)
  • Stereochemistry (30.21%)
  • Internal medicine (22.46%)

What were the highlights of his more recent work (between 2012-2021)?

  • Estrogen receptor (47.33%)
  • Internal medicine (22.46%)
  • Estrogen receptor alpha (18.05%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Estrogen receptor, Internal medicine, Estrogen receptor alpha, Endocrinology and Cancer research. Particularly relevant to Estrogen receptor beta is his body of work in Estrogen receptor. His Estrogen receptor alpha research incorporates themes from Antiestrogen, Receptor, Signal transduction, Regulation of gene expression and In vivo.

His research investigates the link between Endocrinology and topics such as Cell culture that cross with problems in Transgene and Phenotype. The concepts of his Cancer research study are interwoven with issues in Cell growth, Cancer cell, Transcription factor, Breast cancer and Androgen receptor. His study explores the link between Cell biology and topics such as Ligand that cross with problems in Antagonism and Stereochemistry.

Between 2012 and 2021, his most popular works were:

  • PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor–positive breast cancer (243 citations)
  • Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential. (229 citations)
  • Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions (154 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Organic chemistry
  • Gene

John A. Katzenellenbogen mainly investigates Estrogen receptor, Estrogen receptor alpha, Internal medicine, Endocrinology and Cancer research. The study incorporates disciplines such as Estrogen, Pharmacology and Cell growth in addition to Estrogen receptor. His Estrogen receptor alpha research incorporates elements of Tamoxifen, Estrogen receptor beta, Signal transduction, Cell biology and Regulation of gene expression.

His studies in Endocrinology integrate themes in fields like Endometriosis, Lesion, Stromal cell, Angiogenesis and Inflammation. His work deals with themes such as Tumor microenvironment, Cancer cell, Receptor, Cyclin D1 and Breast cancer, which intersect with Cancer research. His Ligand study incorporates themes from Adipose tissue and Stereochemistry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture

Yolande Berthois;John A. Katzenellenbogen;Benita S. Katzenellenbogen.
Proceedings of the National Academy of Sciences of the United States of America (1986)

1569 Citations

Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity.

S. Kousteni;T. Bellido;L. I. Plotkin;C. A. O'Brien.
Cell (2001)

1466 Citations

Pyrazole Ligands: Structure−Affinity/Activity Relationships and Estrogen Receptor-α-Selective Agonists

Shaun R. Stauffer;Christopher J. Coletta;Rosanna Tedesco;Gisele Nishiguchi.
Journal of Medicinal Chemistry (2000)

898 Citations

Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues.

Marvin J. Meyers;Jun Sun;Kathryn E. Carlson;Gwendolyn A. Marriner.
Journal of Medicinal Chemistry (2001)

795 Citations

The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site

Gregory M. Anstead;Kathryn E. Carlson;John A. Katzenellenbogen.
Steroids (1997)

769 Citations

International Union of Pharmacology. LXIV. Estrogen Receptors

Karin Dahlman-Wright;Vincent Cavailles;Suzanne A. Fuqua;V. Craig Jordan.
Pharmacological Reviews (2006)

744 Citations

Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones.

John A. Katzenellenbogen;Bert W. O'Malley;Benita S. Katzenellenbogen.
Molecular Endocrinology (1996)

707 Citations

Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta.

Rajeev S Muthyala;Young H Ju;Shubin Sheng;Lee D Williams.
Bioorganic & Medicinal Chemistry (2004)

555 Citations

Breast cancer: PET imaging of estrogen receptors.

M A Mintun;M J Welch;B A Siegel;C J Mathias.
Radiology (1988)

494 Citations

Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential.

Ilaria Paterni;Carlotta Granchi;John A. Katzenellenbogen;Filippo Minutolo.
Steroids (2014)

475 Citations

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