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Chemistry

D-Index
115
Citations
51110
World Ranking
632
National Ranking
267

Medicine

D-Index
114
Citations
50438
World Ranking
4714
National Ranking
2555

Research.com Recognitions

  • 1974 - Fellow of Alfred P. Sloan Foundation

Overview

John A. Katzenellenbogen is affiliated with the University of Illinois at Urbana-Champaign in the United States. Their research spans biochemistry, genetics, molecular biology, and medicine, focusing extensively on molecular biology and genetics with significant contributions in oncology and radiology.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields within their work include:

  • Molecular Biology
  • Genetics
  • Oncology
  • Radiology, Nuclear Medicine and Imaging
  • Pulmonary and Respiratory Medicine

Their primary research topics are centered on:

  • Estrogen and related hormone effects
  • FOXO transcription factor regulation
  • PARP inhibition in cancer therapy
  • Medical Imaging Techniques and Applications
  • HER2/EGFR in Cancer Research
  • Metabolism, Diabetes, and Cancer
  • DNA Repair Mechanisms

Frequent co-authors collaborating with John A. Katzenellenbogen include:

  • Benita S. Katzenellenbogen
  • Sung Hoon Kim
  • Yvonne Ziegler
  • Kathryn E. Carlson
  • K.W. Nettles

Publications are often found in key venues such as:

  • Cancer Research
  • Nuclear Medicine and Biology
  • Breast Cancer Research and Treatment
  • Cancers
  • Proceedings of the National Academy of Sciences

Representative recent papers authored or co-authored by John A. Katzenellenbogen include:

  • "Targeting the oncogenic transcription factor FOXM1 to improve outcomes in all subtypes of breast cancer", 2023, Breast Cancer Research
  • "Transcription Regulation and Genome Rewiring Governing Sensitivity and Resistance to FOXM1 Inhibition in Breast Cancer", 2021, Cancers
  • "The quest for improving the management of breast cancer by functional imaging: The discovery and development of 16α-[18F]fluoroestradiol (FES), a PET radiotracer for the estrogen receptor, a historical review", 2020, Nuclear Medicine and Biology
  • "FOXM1 regulates glycolysis and energy production in multiple myeloma", 2022, Oncogene
  • "Association of PET-based estradiol-challenge test for breast cancer progesterone receptors with response to endocrine therapy", 2021, Nature Communications

John A. Katzenellenbogen was awarded the Fellow of Alfred P. Sloan Foundation in 1974.

Best Publications

  • Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture

    Yolande Berthois;John A. Katzenellenbogen;Benita S. Katzenellenbogen

  • Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity.

    S. Kousteni;T. Bellido;L. I. Plotkin;C. A. O'Brien

  • Pyrazole Ligands: Structure−Affinity/Activity Relationships and Estrogen Receptor-α-Selective Agonists

    Shaun R. Stauffer;Christopher J. Coletta;Rosanna Tedesco;Gisele Nishiguchi

  • Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues.

    Marvin J. Meyers;Jun Sun;Kathryn E. Carlson;Gwendolyn A. Marriner

  • The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site

    Gregory M. Anstead;Kathryn E. Carlson;John A. Katzenellenbogen

  • International Union of Pharmacology. LXIV. Estrogen Receptors

    Karin Dahlman-Wright;Vincent Cavailles;Suzanne A. Fuqua;V. Craig Jordan

  • Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential.

    Ilaria Paterni;Carlotta Granchi;John A. Katzenellenbogen;Filippo Minutolo

  • Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones.

    John A. Katzenellenbogen;Bert W. O'Malley;Benita S. Katzenellenbogen

  • Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta.

    Rajeev S Muthyala;Young H Ju;Shubin Sheng;Lee D Williams

  • Breast cancer: PET imaging of estrogen receptors.

    M A Mintun;M J Welch;B A Siegel;C J Mathias

  • Metabolic flare: indicator of hormone responsiveness in advanced breast cancer.

    Joanne E. Mortimer;Farrokh Dehdashti;Barry A. Siegel;Kathryn Trinkaus

  • Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.

    Andrew K. Shiau;Danielle Barstad;James T. Radek;Marvin J. Meyers

  • A NOVEL CONNECTOR LINKAGE APPLICABLE IN PRODRUG DESIGN

    P. L. Carl;P. K. Chakravarty;J. A. Katzenellenbogen

  • Characterization of the Biological Roles of the Estrogen Receptors, ERα and ERβ, in Estrogen Target Tissues in Vivo through the Use of an ERα-Selective Ligand

    Heather A. Harris;John A. Katzenellenbogen;Benita S. Katzenellenbogen

  • Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta.

    Jun Sun;Marvin J. Meyers;Brian E. Fink;Ramji Rajendran

  • New stereospecific synthesis of trisubstituted olefins. Stereospecific synthesis of farnesol

    Elias J. Corey;John A. Katzenellenbogen;Gary H. Posner

  • Studies on the uterine, cytoplasmic estrogen binding protein. Thermal stability and ligand dissociation rate. An assay of empty and filled sites by exchange.

    John A. Katzenellenbogen;Howard J. Johnson;Kathryn E. Carlson

  • An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation.

    Kaoru Saijo;Jana G. Collier;Andrew C. Li;John A. Katzenellenbogen

  • PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor–positive breast cancer

    Ana Bosch;Zhiqiang Li;Anna Bergamaschi;Haley Ellis

  • Estrogen receptor transcription and transactivation Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer

    Benita S Katzenellenbogen;John A Katzenellenbogen

  • Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology.

    Benita S. Katzenellenbogen;Inho Choi;Regis Delage-Mourroux;Tracy R. Ediger

  • Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications

    Jean Francois Arnal;Françoise Lenfant;Raphaël Metivier;Gilles Flouriot

  • Coactivator peptides have a differential stabilizing effect on the binding of estrogens and antiestrogens with the estrogen receptor.

    Arvin C. Gee;Kathryn E. Carlson;Paolo G. V. Martini;Benita S. Katzenellenbogen

Frequent Co-Authors

Benita S. Katzenellenbogen
Benita S. Katzenellenbogen University of Illinois at Urbana-Champaign
Kathryn E. Carlson
Kathryn E. Carlson University of Illinois at Urbana-Champaign
Michael J. Welch
Michael J. Welch Washington University in St. Louis
Geoffrey L. Greene
Geoffrey L. Greene University of Chicago
Michael R. Kilbourn
Michael R. Kilbourn University of Michigan–Ann Arbor
Sarat Chandarlapaty
Sarat Chandarlapaty Memorial Sloan Kettering Cancer Center
Scott R. Wilson
Scott R. Wilson University of Illinois at Urbana-Champaign
Farrokh Dehdashti
Farrokh Dehdashti Washington University in St. Louis
Philip W. Shaul
Philip W. Shaul The University of Texas Southwestern Medical Center
Patrick R. Griffin
Patrick R. Griffin Scripps Research Institute

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