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Medicine

D-Index
86
Citations
30337
World Ranking
14020
National Ranking
7113

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Philip W. Shaul is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields including Molecular Biology, Epidemiology, Endocrinology, Diabetes and Metabolism, Surgery, and Immunology.

Their academic output covers various topics, notably:

  • Cholesterol and Lipid Metabolism
  • Estrogen and related hormone effects
  • Adrenal Hormones and Disorders
  • Atherosclerosis and Cardiovascular Diseases
  • Cancer, Lipids, and Metabolism
  • Sepsis Diagnosis and Treatment
  • Hormonal Regulation and Hypertension

Among their recent publications are:

  • Mitochondrial substrate utilization regulates cardiomyocyte cell-cycle progression (2020, Nature Metabolism)
  • Resveratrol intervention attenuates chylomicron secretion via repressing intestinal FXR-induced expression of scavenger receptor SR-B1 (2023, Nature Communications)
  • Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice (2023, Nature Communications)
  • Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis (2020, eLife)
  • Genetic or therapeutic neutralization of ALK1 reduces LDL transcytosis and atherosclerosis in mice (2023, Nature Cardiovascular Research)

Frequent co-authors collaborating with Philip W. Shaul include:

  • Chieko Mineo (29 publications)
  • Anastasia Sacharidou (10 publications)
  • Ling Guo (8 publications)
  • Xiang-An Li (8 publications)
  • Linzhang Huang (7 publications)

Their work appears regularly in well-regarded scientific journals such as:

  • Arteriosclerosis Thrombosis and Vascular Biology (8 publications)
  • Nature Communications (3 publications)
  • Nature Cardiovascular Research (2 publications)
  • Cancers (2 publications)
  • Molecular Metabolism (2 publications)

Philip W. Shaul has also been recognized as a member of the Association of American Physicians, reflecting their engagement with professional medical organizations.

Best Publications

  • HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events

    Anand K Rohatgi;Amit Khera;Jarett D Berry;Edward G. Givens

  • Estrogen receptor α mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen

    Zhong Chen;Ivan S. Yuhanna;Zoya Galcheva-Gargova;Richard H. Karas

  • Demonstration That C-Reactive Protein Decreases eNOS Expression and Bioactivity in Human Aortic Endothelial Cells

    Senthil Kumar Venugopal;Sridevi Devaraj;Ivan Yuhanna;Philip Shaul

  • Inhaled Nitric Oxide and Persistent Pulmonary Hypertension of the Newborn

    Jesse D. Roberts;Jeffrey R. Fineman;Frederick C. Morin;Philip W. Shaul

  • Acylation Targets Endothelial Nitric-oxide Synthase to Plasmalemmal Caveolae

    Philip W. Shaul;Eric J. Smart;Lisa J. Robinson;Zohre German

  • High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase

    Ivan S. Yuhanna;Yan Zhu;Blair E. Cox;Lisa D. Hahner

  • Endothelial and Antithrombotic Actions of HDL

    Chieko Mineo;Hiroshi Deguchi;John H. Griffin;Philip W. Shaul

  • Regulation of Endothelial Nitric Oxide Synthase: Location, Location, Location

    Philip W. Shaul

  • Estrogen modulation of endothelial nitric oxide synthase.

    Ken L. Chambliss;Philip W. Shaul

  • Role of plasmalemmal caveolae in signal transduction

    Philip W. Shaul;Richard G. W. Anderson

  • Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β

    Yan Zhu;Zhao Bian;Ping Lu;Richard H. Karas

  • Estrogen receptor alpha and endothelial nitric oxide synthase are organized into a functional signaling module in caveolae.

    Ken L. Chambliss;Ivan S. Yuhanna;Chieko Mineo;Pingsheng Liu

  • Oxidized Low Density Lipoprotein Displaces Endothelial Nitric-oxide Synthase (eNOS) from Plasmalemmal Caveolae and Impairs eNOS Activation

    Alison Blair;Philip W. Shaul;Ivan S. Yuhanna;Patricia A. Conrad

  • High Density Lipoprotein-induced Endothelial Nitric-oxide Synthase Activation Is Mediated by Akt and MAP Kinases *

    Chieko Mineo;Ivan S. Yuhanna;Michael J. Quon;Philip W. Shaul

  • 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen

    Michihisa Umetani;Hideharu Domoto;Andrew K Gormley;Ivan S Yuhanna

  • Estrogen Upregulates Endothelial Nitric Oxide Synthase Gene Expression in Fetal Pulmonary Artery Endothelium

    Amy N. MacRitchie;Sandy S. Jun;Zhong Chen;Zohre German

  • High Density Lipoprotein Prevents Oxidized Low Density Lipoprotein-induced Inhibition of Endothelial Nitric-oxide Synthase Localization and Activation in Caveolae

    Annette Uittenbogaard;Philip W. Shaul;Ivan S. Yuhanna;Alison Blair

  • Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium.

    Regina L. Lantin-Hermoso;Charles R. Rosenfeld;Ivan S. Yuhanna;Zohre German

  • 27-Hydroxycholesterol Is an Endogenous Selective Estrogen Receptor Modulator

    Carolyn D. DuSell;Michihisa Umetani;Philip W. Shaul;David J. Mangelsdorf

  • Plasma Membrane Estrogen Receptors Are Coupled to Endothelial Nitric-oxide Synthase through Gαi

    Myra H. Wyckoff;Ken L. Chambliss;Chieko Mineo;Ivan S. Yuhanna

Frequent Co-Authors

William Oh
William Oh Icahn School of Medicine at Mount Sinai
John A. Katzenellenbogen
John A. Katzenellenbogen University of Illinois at Urbana-Champaign
Benita S. Katzenellenbogen
Benita S. Katzenellenbogen University of Illinois at Urbana-Champaign
Joachim Herz
Joachim Herz The University of Texas Southwestern Medical Center
Richard G. W. Anderson
Richard G. W. Anderson The University of Texas Southwestern Medical Center
Jane E. Salmon
Jane E. Salmon Hospital for Special Surgery
Barbara S. Stonestreet
Barbara S. Stonestreet Brown University
L. M. Buja
L. M. Buja The University of Texas Health Science Center at Houston
Eric J. Smart
Eric J. Smart University of Kentucky
Kenneth S. Korach
Kenneth S. Korach National Institutes of Health

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