What is she best known for?
The fields of study she is best known for:
- Enzyme
- Organic chemistry
- Biochemistry
The scientist’s investigation covers issues in Estrogen receptor, Stereochemistry, Estrogen receptor alpha, Ligand and Biochemistry.
Her Estrogen receptor research incorporates themes from Receptor, Tamoxifen, Nuclear receptor, Estrogen and Binding site.
The various areas that she examines in her Stereochemistry study include Molecule, Binding selectivity, Chemical synthesis, Double bond and Isostructural.
Her work is dedicated to discovering how Estrogen receptor alpha, Estrogen receptor beta are connected with Nuclear receptor coactivator 3 and Endocrinology and other disciplines.
In her study, Estradiol binding, Ligand binding assay, Amino acid, Pharmacophore and Ligand efficiency is strongly linked to Cooperative binding, which falls under the umbrella field of Ligand.
Her Biochemistry study incorporates themes from Promoter and Pyrazine.
Her most cited work include:
- Estrogen receptor-β potency-selective ligands: Structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues (605 citations)
- The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site (518 citations)
- Synthesis and biological evaluation of a novel series of furans: Ligands selective for estrogen receptor α (179 citations)
What are the main themes of her work throughout her whole career to date?
Her primary scientific interests are in Estrogen receptor, Stereochemistry, Receptor, Ligand and Estrogen receptor alpha.
She has researched Estrogen receptor in several fields, including Biochemistry, Estrogen and Cell biology.
Her research integrates issues of Ligand, Structure–activity relationship, Chemical synthesis and Binding site in her study of Stereochemistry.
Her research investigates the link between Chemical synthesis and topics such as Molecular model that cross with problems in Docking.
Kathryn E. Carlson combines subjects such as Endocrinology, Uterus, Estrogen receptor binding, Steric effects and Progesterone receptor with her study of Receptor.
Her Estrogen receptor alpha study combines topics from a wide range of disciplines, such as Antiestrogen, Tamoxifen, Bazedoxifene and Cancer research.
She most often published in these fields:
- Estrogen receptor (68.18%)
- Stereochemistry (40.91%)
- Receptor (26.52%)
What were the highlights of her more recent work (between 2015-2021)?
- Estrogen receptor (68.18%)
- Estrogen receptor alpha (24.24%)
- Cancer research (13.64%)
In recent papers she was focusing on the following fields of study:
Her scientific interests lie mostly in Estrogen receptor, Estrogen receptor alpha, Cancer research, Antiestrogen and Breast cancer.
Her studies deal with areas such as Tamoxifen, Receptor, Ligand and Cell biology as well as Estrogen receptor.
Her study focuses on the intersection of Receptor and fields such as Coactivator with connections in the field of Biochemistry.
Her Estrogen receptor alpha study incorporates themes from Fulvestrant, Stereochemistry, Pharmacology, Binding site and Bazedoxifene.
Her studies in Stereochemistry integrate themes in fields like Protein structure, Reporter gene and Structure–activity relationship.
Her Antiestrogen research focuses on Selective estrogen receptor modulator and how it relates to Potency and Isoliquiritigenin.
Between 2015 and 2021, her most popular works were:
- Activating ESR1 Mutations Differentially Affect the Efficacy of ER Antagonists (153 citations)
- Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation (137 citations)
- Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. (63 citations)
In her most recent research, the most cited papers focused on:
- Enzyme
- Organic chemistry
- Biochemistry
Her primary areas of study are Estrogen receptor alpha, Estrogen receptor, Tamoxifen, Pharmacology and Antiestrogen.
Her Estrogen receptor alpha research integrates issues from Nuclear receptor and Signal transduction, Cell biology.
Her Nuclear receptor study combines topics in areas such as Cell growth and Ligand.
As part of her studies on Estrogen receptor, Kathryn E. Carlson frequently links adjacent subjects like Endocrinology.
Kathryn E. Carlson has included themes like Cancer, Receptor, Fulvestrant, Estrogen Receptor Antagonists and Estrogen in her Pharmacology study.
The concepts of her Antiestrogen study are interwoven with issues in Agonist and Isoliquiritigenin.
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