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Francisco Silveira Guimarães

Francisco Silveira Guimarães

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Neuroscience
Brazil
2026

D-Index & Metrics

Neuroscience

D-Index
87
Citations
25123
World Ranking
1262
National Ranking
4

Medicine

D-Index
87
Citations
25104
World Ranking
13744
National Ranking
38

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Brazil Leader Award
  • 2025 - Research.com Neuroscience in Brazil Leader Award

Overview

Francisco Silveira Guimarães is affiliated with the Universidade de São Paulo in Brazil. Their research spans multiple domains within medicine and neuroscience, with a significant focus on pharmacology and neuropsychopharmacology. The scientist has contributed extensively to fields such as cellular and molecular neuroscience, psychiatry and mental health, cognitive neuroscience, and biological psychiatry.

The research topics covered by Francisco Silveira Guimarães include:

  • Cannabis and Cannabinoid Research
  • Neuroscience and Neuropharmacology Research
  • Neurotransmitter Receptor Influence on Behavior
  • Tryptophan and Brain Disorders
  • Stress Responses and Cortisol
  • Bipolar Disorder and Treatment
  • Sleep and Wakefulness Research

Recent publications authored or co-authored by Francisco Silveira Guimarães include:

  • Efficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health Care Workers During the COVID-19 Pandemic, 2021, JAMA Network Open
  • Cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-HT1A, but not CB1 and CB2 receptors, 2020, Pharmacological Research
  • Serious adverse effects of cannabidiol (CBD): a review of randomized controlled trials, 2020, Expert Opinion on Drug Metabolism & Toxicology
  • CBD modulates DNA methylation in the prefrontal cortex and hippocampus of mice exposed to forced swim, 2020, Behavioural Brain Research
  • Adverse Effects of Oral Cannabidiol: An Updated Systematic Review of Randomized Controlled Trials (2020-2022), 2022, Pharmaceutics

The scientist frequently collaborates with several co-authors, including:

  • Felipe V. Gomes
  • Antônio Waldo Zuardi
  • Alline C. Campos
  • Jaime E. C. Hallak
  • Elaine Aparecida Del Bel

Francisco Silveira Guimarães often publishes in journals such as:

  • IBRO Neuroscience Reports
  • Neuropharmacology
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • Cannabis and Cannabinoid Research
  • Behavioural Brain Research

The combination of their research includes both clinical and preclinical studies, addressing pharmacological effects and neurobiological mechanisms of cannabinoids, with implications for psychiatric conditions and stress-related disorders. The work broadens understanding of cannabinoid influence on brain function, behavior, and the molecular underpinnings of neuropsychiatric diseases.

Best Publications

  • Role of 5-HT in stress, anxiety, and depression

    Frederico Guilherme Graeff;Francisco Silveira Guimarães;T G C S De Andrade;J F W Deakin

  • Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug.

    A.W. Zuardi;J.A.S. Crippa;J.E.C. Hallak;F.A. Moreira

  • Animal models of anxiety disorders and stress

    Alline C. Campos;Manoela V. Fogaça;Daniele C. Aguiar;Francisco S. Guimarães

  • Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

    Alline Cristina Campos;Fabricio Araújo Moreira;Felipe Villela Gomes;Elaine Aparecida Del Bel

  • Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors

    T. V. Zanelati;C. Biojone;F. A. Moreira;Francisco Silveira Guimarães

  • Cannabidiol, neuroprotection and neuropsychiatric disorders.

    Alline C. Campos;Manoela V. Fogaça;Andreza B. Sonego;Francisco S. Guimarães

  • Effects of ipsapirone and cannabidiol on human experimental anxiety.

    A W Zuardi;R A Cosme;F G Graeff;F S Guimarães

  • Antianxiety effect of cannabidiol in the elevated plus-maze

    Francisco Silveira Guimarães;T M Chiaretti;Frederico Guilherme Graeff;A W Zuardi

  • Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats.

    Alline Cristina Campos;Francisco Silveira Guimarães

  • 5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats.

    Leonardo B.M. Resstel;Rodrigo F. Tavares;Sabrina F.S. Lisboa;Sâmia R.L. Joca

  • Antipsychotic Effect of Cannabidiol

    A. W. Zuardi;S. L. Morais;F. S. Guimarães;R. Mechoulam

  • The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system

    Alline C. Campos;Zaira Ortega;Javier Palazuelos;Manoela V. Fogaça

  • Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age.

    José A. Crippa;José A. Crippa;Francisco S. Guimarães;Francisco S. Guimarães;Alline C. Campos;Alline C. Campos;Antonio W. Zuardi;Antonio W. Zuardi

  • Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life

    Antonio W. Zuardi;Antonio W. Zuardi;Natália P. Rodrigues;Angélica L. Silva;Sandra A. Bernardo

  • A Critical Review of the Antipsychotic Effects of Cannabidiol: 30 Years of a Translational Investigation

    Antonio Waldo Zuardi;José Alexandre de Souza Crippa;José Alexandre de Souza Crippa;Jaime Eduardo Cecílio Hallak;Sagnik Bhattacharyya

  • Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test.

    Ila M Linares;Antonio W Zuardi;Antonio W Zuardi;Luis C Pereira;Regina H Queiroz

  • Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice

    Fabrício A. Moreira;Francisco Silveira Guimarães

  • Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects

    Sâmia Regiane Lourenço Joca;Francisco Silveira Guimarães

  • Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test.

    Fabrício A. Moreira;Daniele C. Aguiar;Francisco Silveira Guimarães

  • The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors

    Felipe V. Gomes;Leonardo Barbosa Moraes Resstel;Francisco Silveira Guimarães

Frequent Co-Authors

Frederico Guilherme Graeff
Frederico Guilherme Graeff Universidade de São Paulo
Fernando M.A. Corrêa
Fernando M.A. Corrêa Universidade de São Paulo
Antonio Waldo Zuardi
Antonio Waldo Zuardi Universidade de São Paulo
José Alexandre de Souza Crippa
José Alexandre de Souza Crippa Universidade de São Paulo
John Francis William Deakin
John Francis William Deakin University of Manchester
Hélio Zangrossi
Hélio Zangrossi Universidade de São Paulo
Eero Castrén
Eero Castrén University of Helsinki
Fernando Q. Cunha
Fernando Q. Cunha Universidade de São Paulo
Reinaldo N. Takahashi
Reinaldo N. Takahashi Universidade Federal de Santa Catarina
Ismael Galve-Roperh
Ismael Galve-Roperh Complutense University of Madrid

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