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Medicine
Israel
2023

D-Index & Metrics

Medicine

D-Index
131
Citations
70320
World Ranking
2383
National Ranking
4

Research.com Recognitions

  • 2023 - Research.com Medicine in Israel Leader Award
  • 2022 - Research.com Medicine in Israel Leader Award

Overview

Raphael Mechoulam was affiliated with the Hebrew University of Jerusalem in Israel. Their research primarily focused on medicine, with extensive work in pharmacology, cellular and molecular neuroscience, molecular biology, physiology, and materials chemistry.

The scientist's main topics of research covered cannabis and cannabinoid research, neurotransmitter receptor influence on behavior, polyamine metabolism and applications, crystallization and solubility studies, X-ray diffraction in crystallography, diet and metabolism studies, and bipolar disorder and treatment.

Raphael Mechoulam published several recent papers, including:

  • Efficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health Care Workers During the COVID-19 Pandemic, 2021, JAMA Network Open
  • Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in schizophrenia: Analyses in patients and in perinatal Δ9-tetrahydrocannabinol-exposed rats, 2020, Pharmacological Research
  • Anti-Biofilm Activity of Cannabidiol against Candida albicans, 2021, Microorganisms
  • Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment, 2020, Biochemical Pharmacology
  • Adherence, Safety, and Effectiveness of Medical Cannabis and Epidemiological Characteristics of the Patient Population: A Prospective Study, 2022, Frontiers in Medicine

The frequent coauthors working alongside Mechoulam included Reem Smoum, Linda A. Parker, Vincenzo Di Marzo, Erin M. Rock, and Ruth Gallily.

Publications appeared most commonly in the following venues:

  • Cannabis and Cannabinoid Research
  • The Cambridge Structural Database
  • Molecules
  • Psychopharmacology
  • Frontiers in Pharmacology

Mechoulam also contributed to scholarly books, with a notable publication titled CBD released by The MIT Press in 2022.

Best Publications

  • ISOLATION AND STRUCTURE OF A BRAIN CONSTITUENT THAT BINDS TO THE CANNABINOID RECEPTOR

    William A. Devane;Lumir Hanuš;Aviva Breuer;Roger G. Pertwee

  • International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors

    A C Howlett;F Barth;T I Bonner;G Cabral

  • Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors.

    Raphael Mechoulam;Shimon Ben-Shabat;Lumir Hanus;Moshe Ligumsky

  • International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

    Roger Guy Pertwee;A. C. Howlett;M. E. Abood;S. P. H. Alexander

  • Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.

    Tiziana Bisogno;Lumír Hanuš;Luciano De Petrocellis;Susanna Tchilibon

  • The Endocannabinoid System and the Brain

    Raphael Mechoulam;Linda A. Parker

  • 2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor

    Lumír Hanuš;Saleh Abu-Lafi;Ester Fride;Aviva Breuer

  • Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

    Angelo A. Izzo;Francesca Borrelli;Raffaele Capasso;Vincenzo Di Marzo

  • An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

    David Panikashvili;Constantina Simeonidou;Shimon Ben-Shabat;Lumír Hanuš

  • The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

    A. M. Malfait;R. Gallily;P. F. Sumariwalla;A. S. Malik

  • Chronic Administration of Cannabidiol to Healthy Volunteers and Epileptic Patients

    Jomar M. Cunha;E.A. Carlini;Aparecido E. Pereira;Oswaldo L. Ramos

  • An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity.

    Shimon Ben-Shabat;Ester Fride;Tzviel Sheskin;Tsippy Tamiri

  • HU-308: A specific agonist for CB2, a peripheral cannabinoid receptor

    L. Hanuš;A. Breuer;S. Tchilibon;S. Shiloah

  • Endocannabinoid signaling at the periphery: 50 years after THC

    Mauro Maccarrone;Itai Bab;Tamás Bíró;Guy A. Cabral

  • Cannabidiol – Recent Advances

    Raphael Mechoulam;Maximilian Peters;Eric Murillo‐Rodriguez;Lumír O. Hanuš

  • Cannabidiol: an overview of some pharmacological aspects.

    Raphael Mechoulam;Linda A. Parker;Ruth Gallily

  • Peripheral cannabinoid receptor, CB2, regulates bone mass

    Orr Ofek;Meliha Karsak;Nathalie Leclerc;Meirav Fogel

  • Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent

    Ester Fride;Raphael Mechoulam

  • The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice.

    P B Smith;D R Compton;S P Welch;R K Razdan

  • Is lipid signaling through cannabinoid 2 receptors part of a protective system

    P. Pacher;R. Mechoulam

Frequent Co-Authors

Esther Shohami
Esther Shohami Hebrew University of Jerusalem
Linda A. Parker
Linda A. Parker University of Guelph
Vincenzo Di Marzo
Vincenzo Di Marzo National Research Council (CNR)
Roger G. Pertwee
Roger G. Pertwee University of Aberdeen
Zvi Vogel
Zvi Vogel Weizmann Institute of Science
Filippo Drago
Filippo Drago University of Catania
Pal Pacher
Pal Pacher National Institutes of Health
Mauro Maccarrone
Mauro Maccarrone University of L'Aquila
Anat Biegon
Anat Biegon Stony Brook University
Javier Fernández-Ruiz
Javier Fernández-Ruiz Complutense University of Madrid

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