2020 - Fellow, National Academy of Inventors
2011 - Fellow of the American Association for the Advancement of Science (AAAS)
His primary scientific interests are in Estrogen receptor, Receptor, Internal medicine, Endocrinology and Cell biology. His biological study spans a wide range of topics, including Cell and Estrogen. He combines subjects such as Biological activity, Response element, Transcription factor and Progesterone receptor with his study of Receptor.
His research in Internal medicine intersects with topics in Pharmacology and Mechanism of action. The study incorporates disciplines such as Tamoxifen, Raloxifene and Cancer research in addition to Endocrinology. His Cell biology research incorporates themes from Nuclear receptor, Cellular differentiation, Enzyme-linked receptor and Molecular biology.
His scientific interests lie mostly in Estrogen receptor, Receptor, Internal medicine, Cancer research and Endocrinology. His Estrogen receptor research is multidisciplinary, relying on both Estrogen and Pharmacology. He has included themes like Nuclear receptor, Transcription factor and Signal transduction, Cell biology in his Receptor study.
His Cell biology research incorporates elements of Molecular biology, Steroid hormone, Retinoic acid and Promoter. His work carried out in the field of Cancer research brings together such families of science as Cancer cell, Cancer, Prostate cancer, Androgen receptor and Cell growth. His Endocrinology research integrates issues from Steroid hormone receptor and Progesterone receptor.
Donald P. McDonnell focuses on Cancer research, Breast cancer, Cancer, Estrogen receptor and Internal medicine. His Cancer research research includes elements of Cell growth, Cancer cell, Endocrine therapy and Prostate cancer, Androgen receptor. Donald P. McDonnell has researched Androgen receptor in several fields, including Molecular biology and Transcription factor.
His Estrogen receptor research is multidisciplinary, incorporating elements of Tamoxifen and Pharmacology. The concepts of his Internal medicine study are interwoven with issues in Endocrinology and Oncology. His Endocrinology study combines topics from a wide range of disciplines, such as Receptor, Regulation of gene expression and Progesterone receptor.
Cancer research, Estrogen receptor, Breast cancer, Pharmacology and Cancer are his primary areas of study. His studies deal with areas such as Liver X receptor and Tamoxifen as well as Estrogen receptor. His study in Pharmacology is interdisciplinary in nature, drawing from both Cancer cell, Androgen receptor and Agonist.
His Estrogen receptor alpha study combines topics in areas such as FOXA1, Estrogen receptor beta and AGR2. His research on Endocrinology and Internal medicine is centered around CYP27A1. In his study, Receptor is strongly linked to Nuclear receptor, which falls under the umbrella field of PI3K/AKT/mTOR pathway.
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The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens.
Julie M. Hall;Donald P. McDonnell.
Cloning and expression of full-length cDNA encoding human vitamin D receptor.
A. R. Baker;D. P. McDonnell;M. Hughes;T. M. Crisp.
Proceedings of the National Academy of Sciences of the United States of America (1988)
Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.
E Vegeto;M M Shahbaz;D X Wen;M E Goldman.
Molecular Endocrinology (1993)
Evaluation of Chemicals with Endocrine Modulating Activity in a Yeast-Based Steroid Hormone Receptor Gene Transcription Assay
Kevin W. Gaido;Linda S. Leonard;Stephanie Lovell;Janet C. Gould.
Toxicology and Applied Pharmacology (1997)
Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.
M T Tzukerman;A Esty;D Santiso-Mere;P Danielian.
Molecular Endocrinology (1994)
Connections and Regulation of the Human Estrogen Receptor
Donald P. McDonnell;John D. Norris.
Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.
D P McDonnell;D L Clemm;T Hermann;M E Goldman.
Molecular Endocrinology (1995)
Molecular cloning of complementary DNA encoding the avian receptor for vitamin D.
Donald P. Mcdonnell;David J. Mangelsdorf;J. Wesley Pike;Mark R. Haussler.
27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology
Erik R. Nelson;Suzanne E. Wardell;Jeff S. Jasper;Sunghee Park.
Bisphenol A interacts with the estrogen receptor alpha in a distinct manner from estradiol.
Janet C. Gould;Linda S. Leonard;Susan C. Maness;Brandee L. Wagner.
Molecular and Cellular Endocrinology (1998)
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