World's Best Scientists 2026 revealed!
Donald P. McDonnell

Donald P. McDonnell

D-Index & Metrics

Biology and Biochemistry

D-Index
116
Citations
44715
World Ranking
756
National Ranking
477

Donald P. McDonnell publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Donald P. McDonnell sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 377 publications — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Donald P. McDonnell D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Donald P. McDonnell sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 116 D-Index — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2020 - Fellow, National Academy of Inventors
  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Donald P. McDonnell is affiliated with Duke University in the United States. Their research focuses broadly on biochemistry, genetics, and molecular biology, alongside significant contributions to medicine. Within these domains, their work frequently addresses molecular biology, immunology, genetics, oncology, and pulmonary and respiratory medicine.

Key topics in their research include estrogen and related hormone effects, immune cell function and interaction, prostate cancer treatment and research, cancer-related molecular pathways, immune cells in cancer, advanced breast cancer therapies, and cancer, hypoxia, and metabolism.

McDonnell has published extensively in prominent venues where they have multiple contributions. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Cancer Immunology Research, Clinical Cancer Research, Cancer Research, and UNC Libraries.

Frequent collaborators in McDonnell's research include Ching-yi Chang, Suzanne E. Wardell, Sandeep Artham, John D. Norris, and Binita Chakraborty.

Selected recent publications are as follows:

  • "Dysregulated cholesterol homeostasis results in resistance to ferroptosis increasing tumorigenicity and metastasis in cancer," 2021, Nature Communications
  • "Estrogen Receptor Signaling in the Immune System," 2022, Endocrine Reviews
  • "The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand-activated WT Receptor," 2020, Molecular Cancer Therapeutics
  • "Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice," 2023, Nature Communications
  • "Next-Generation Endocrine Therapies for Breast Cancer," 2021, Journal of Clinical Oncology

McDonnell has been recognized with several awards, including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2011 and a Fellow of the National Academy of Inventors in 2020.

Best Publications

  • The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens.

    Julie M. Hall;Donald P. McDonnell

  • Cloning and expression of full-length cDNA encoding human vitamin D receptor.

    A. R. Baker;D. P. McDonnell;M. Hughes;T. M. Crisp

  • Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

    E Vegeto;M M Shahbaz;D X Wen;M E Goldman

  • Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.

    M T Tzukerman;A Esty;D Santiso-Mere;P Danielian

  • Evaluation of Chemicals with Endocrine Modulating Activity in a Yeast-Based Steroid Hormone Receptor Gene Transcription Assay

    Kevin W. Gaido;Linda S. Leonard;Stephanie Lovell;Janet C. Gould

  • 27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology

    Erik R. Nelson;Suzanne E. Wardell;Jeff S. Jasper;Sunghee Park

  • Connections and Regulation of the Human Estrogen Receptor

    Donald P. McDonnell;John D. Norris

  • Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.

    D P McDonnell;D L Clemm;T Hermann;M E Goldman

  • Molecular cloning of complementary DNA encoding the avian receptor for vitamin D.

    Donald P. Mcdonnell;David J. Mangelsdorf;J. Wesley Pike;Mark R. Haussler

  • Bisphenol A interacts with the estrogen receptor α in a distinct manner from estradiol

    Janet C. Gould;Linda S. Leonard;Susan C. Maness;Brandee L. Wagner

  • Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells

    John P. Chute;Garrett G. Muramoto;John Whitesides;Michael Colvin

  • The Human Estrogen Receptor-α Is a Ubiquitinated Protein Whose Stability Is Affected Differentially by Agonists, Antagonists, and Selective Estrogen Receptor Modulators

    Ashini L. Wijayaratne;Donald P. McDonnell

  • Variant Human Breast Tumor Estrogen Receptor with Constitutive Transcriptional Activity

    Suzanne A. W. Fuqua;Saundra D. Fitzgerald;Gary C. Chamness;Atul K. Tandon

  • Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta

    Lisa A. Paige;Dale J. Christensen;Hanne Grøn;John D. Norris

  • International Union of Pharmacology. LXV. The Pharmacology and Classification of the Nuclear Receptor Superfamily: Glucocorticoid, Mineralocorticoid, Progesterone, and Androgen Receptors

    Nick Z. Lu;Suzanne E. Wardell;Kerry L. Burnstein;Donald Defranco

  • Estrogen levels in childhood determined by an ultrasensitive recombinant cell bioassay.

    Karen Oerter Klein;Jeffrey Baron;Michael J. Colli;Donald P. McDonnell

  • The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells.

    D. X. Wen;You-Feng Xu;D. E. Mais;M. E. Goldman

  • Peptide Antagonists of the Human Estrogen Receptor

    John D. Norris;Lisa A. Paige;Dale J. Christensen;Ching-Yi Chang

  • The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor.

    Elisabetta Vegeto;George F. Allan;William T. Schrader;Ming-Jer Tsai

  • Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β

    Ching Yi Chang;John D. Norris;Hanne Grøn;Lisa A. Paige

Frequent Co-Authors

Bert W. O'Malley
Bert W. O'Malley Baylor College of Medicine
Jeffrey C. Rathmell
Jeffrey C. Rathmell Vanderbilt University Medical Center
J. Wesley Pike
J. Wesley Pike University of Wisconsin–Madison
William T. Schrader
William T. Schrader Baylor College of Medicine
Stephen Safe
Stephen Safe Texas A&M University
Nelson J. Chao
Nelson J. Chao Duke University
Zafar Nawaz
Zafar Nawaz University of Miami
Myles Brown
Myles Brown Harvard University
Ming-Jer Tsai
Ming-Jer Tsai Baylor College of Medicine
Nancy L. Weigel
Nancy L. Weigel Baylor College of Medicine

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