What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Estrogen receptor, Receptor, Internal medicine, Endocrinology and Cell biology.
His biological study spans a wide range of topics, including Cell and Estrogen.
He combines subjects such as Biological activity, Response element, Transcription factor and Progesterone receptor with his study of Receptor.
His research in Internal medicine intersects with topics in Pharmacology and Mechanism of action.
The study incorporates disciplines such as Tamoxifen, Raloxifene and Cancer research in addition to Endocrinology.
His Cell biology research incorporates themes from Nuclear receptor, Cellular differentiation, Enzyme-linked receptor and Molecular biology.
His most cited work include:
- The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens. (955 citations)
- Cloning and expression of full-length cDNA encoding human vitamin D receptor. (825 citations)
- Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. (704 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Estrogen receptor, Receptor, Internal medicine, Cancer research and Endocrinology.
His Estrogen receptor research is multidisciplinary, relying on both Estrogen and Pharmacology.
He has included themes like Nuclear receptor, Transcription factor and Signal transduction, Cell biology in his Receptor study.
His Cell biology research incorporates elements of Molecular biology, Steroid hormone, Retinoic acid and Promoter.
His work carried out in the field of Cancer research brings together such families of science as Cancer cell, Cancer, Prostate cancer, Androgen receptor and Cell growth.
His Endocrinology research integrates issues from Steroid hormone receptor and Progesterone receptor.
He most often published in these fields:
- Estrogen receptor (34.62%)
- Receptor (27.22%)
- Internal medicine (26.04%)
What were the highlights of his more recent work (between 2013-2021)?
- Cancer research (23.37%)
- Breast cancer (14.50%)
- Cancer (11.83%)
In recent papers he was focusing on the following fields of study:
Donald P. McDonnell focuses on Cancer research, Breast cancer, Cancer, Estrogen receptor and Internal medicine.
His Cancer research research includes elements of Cell growth, Cancer cell, Endocrine therapy and Prostate cancer, Androgen receptor.
Donald P. McDonnell has researched Androgen receptor in several fields, including Molecular biology and Transcription factor.
His Estrogen receptor research is multidisciplinary, incorporating elements of Tamoxifen and Pharmacology.
The concepts of his Internal medicine study are interwoven with issues in Endocrinology and Oncology.
His Endocrinology study combines topics from a wide range of disciplines, such as Receptor, Regulation of gene expression and Progesterone receptor.
Between 2013 and 2021, his most popular works were:
- Systematic identification of signaling pathways with potential to confer anticancer drug resistance. (115 citations)
- The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells. (114 citations)
- Oral Selective Estrogen Receptor Downregulators (SERDs), a Breakthrough Endocrine Therapy for Breast Cancer. (98 citations)
In his most recent research, the most cited papers focused on:
Cancer research, Estrogen receptor, Breast cancer, Pharmacology and Cancer are his primary areas of study.
His studies deal with areas such as Liver X receptor and Tamoxifen as well as Estrogen receptor.
His study in Pharmacology is interdisciplinary in nature, drawing from both Cancer cell, Androgen receptor and Agonist.
His Estrogen receptor alpha study combines topics in areas such as FOXA1, Estrogen receptor beta and AGR2.
His research on Endocrinology and Internal medicine is centered around CYP27A1.
In his study, Receptor is strongly linked to Nuclear receptor, which falls under the umbrella field of PI3K/AKT/mTOR pathway.
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