Shane A. Liddelow

Overview

Best Publications

• Neurotoxic reactive astrocytes are induced by activated microglia

  Shane A. Liddelow;Kevin A. Guttenplan;Laura E. Clarke;Frederick C. Bennett

  7813
  Citations

• An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

  Ye Zhang;Kenian Chen;Steven A Sloan;Mariko L Bennett

  5393
  Citations

• Reactive Astrocytes: Production, Function, and Therapeutic Potential

  Shane A. Liddelow;Ben A. Barres

  2267
  Citations

• Reactive astrocyte nomenclature, definitions, and future directions

  Carole Escartin;Elena Galea;András Lakatos;James P. O’Callaghan

  2183
  Citations

• New tools for studying microglia in the mouse and human CNS.

  Mariko L. Bennett;F. Chris Bennett;Shane A. Liddelow;Shane A. Liddelow;Bahareh Ajami

  1908
  Citations

• Normal aging induces A1-like astrocyte reactivity

  Laura E. Clarke;Shane A. Liddelow;Chandrani Chakraborty;Alexandra E. Münch

  1276
  Citations

• ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

  Yang Shi;Kaoru Yamada;Shane Antony Liddelow;Shane Antony Liddelow;Scott T. Smith

  1191
  Citations

• Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease

  Seung Pil Yun;Tae In Kam;Nikhil Panicker;Sangmin Kim

  1088
  Citations

• Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation

  Unknown

  681
  Citations

• Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.

  Ilia D. Vainchtein;Gregory Chin;Frances S. Cho;Kevin W. Kelley

  610
  Citations

• Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

  Amit U. Joshi;Paras S. Minhas;Shane A. Liddelow;Shane A. Liddelow;Shane A. Liddelow;Bereketeab Haileselassie

  559
  Citations

• Neurotoxic reactive astrocytes induce cell death via saturated lipids

  Kevin A. Guttenplan;Maya K. Weigel;Priya Prakash;Prageeth R. Wijewardhane

  531
  Citations

• Neuroinflammatory astrocyte subtypes in the mouse brain.

  Philip Hasel;Indigo V L Rose;Jessica S Sadick;Rachel D Kim

  526
  Citations

• Barrier Mechanisms in the Developing Brain

  Norman R. Saunders;Shane A. Liddelow;Katarzyna M. Dziegielewska

  522
  Citations

• Functional roles of reactive astrocytes in neuroinflammation and neurodegeneration

  Unknown

  472
  Citations

• Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease

  Unknown

  468
  Citations

• Solving neurodegeneration: common mechanisms and strategies for new treatments

  Unknown

  357
  Citations

• Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment

  Erin M. Gibson;Surya Nagaraja;Alfonso Ocampo;Lydia T. Tam

  342
  Citations

• Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model

  Kevin A. Guttenplan;Maya K. Weigel;Drew I. Adler;Julien Couthouis

  265
  Citations

• Development of the choroid plexus and blood-CSF barrier.

  Shane A. Liddelow

  239
  Citations

• Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury

  Kevin A. Guttenplan;Benjamin K. Stafford;Rana N. El-Danaf;Drew I. Adler

  199
  Citations

• The blood–CSF barrier explained: when development is not immaturity

  Pia A. Johansson;Katarzyna M. Dziegielewska;Shane A. Liddelow;Norman R. Saunders

  187
  Citations

• Microglia and Astrocytes in Disease: Dynamic Duo or Partners in Crime?

  Shane A. Liddelow;Samuel E. Marsh;Samuel E. Marsh;Samuel E. Marsh;Beth Stevens

  175
  Citations

• PL-03-01: INGE GRUNDKE-IQBAL AWARD FOR ALZHEIMER'S RESEARCH: NEUROTOXIC REACTIVE ASTROCYTES ARE INDUCED BY ACTIVATED MICROGLIA

  Shane A. Liddelow

  0
  Citations