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Biology and Biochemistry

D-Index
64
Citations
15785
World Ranking
9599
National Ranking
4239

Overview

Eric B. Dammer is an active researcher affiliated with Emory University in the United States, specializing primarily in medicine and biochemistry, genetics, and molecular biology. Their work spans several subfields including molecular biology, physiology, neurology, biological psychiatry, and spectroscopy.

The research focus of Eric B. Dammer largely covers Alzheimer's disease research and treatments, with additional interests in bioinformatics and genomic networks, neuroinflammation and neurodegeneration mechanisms, tryptophan and brain disorders, metabolomics and mass spectrometry studies, advanced proteomics techniques and applications, as well as S100 proteins and annexins.

The scientist has contributed to numerous publications with some of the most frequent publication venues including bioRxiv (Cold Spring Harbor Laboratory), Alzheimer's & Dementia, Molecular Neurodegeneration, Nature Communications, and Nature Aging.

Recent notable papers by Eric B. Dammer include:

  • Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation, 2020, Nature Medicine
  • Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level, 2022, Nature Neuroscience
  • Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease, 2020, Science Advances
  • Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis, 2021, Nature Genetics
  • Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions, 2020, Scientific Data

Frequent co-authors working with Eric B. Dammer include:

  • Nicholas T. Seyfried
  • Allan I. Levey
  • Duc M. Duong
  • James J. Lah
  • Erik C. B. Johnson

Best Publications

  • Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

    Erik C.B. Johnson;Eric B. Dammer;Duc M. Duong;Lingyan Ping

  • The endosomal-lysosomal system: from acidification and cargo sorting to neurodegeneration.

    Yong Bo Hu;Eric B. Dammer;Ru Jing Ren;Gang Wang

  • The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.

    Minghui Wang;Noam D. Beckmann;Panos Roussos;Erming Wang

  • Identification of neuronal RNA targets of TDP-43-containing Ribonucleoprotein complexes

    Chantelle F. Sephton;Can Cenik;Alper Kucukural;Eric B. Dammer

  • A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease

    Nicholas T. Seyfried;Eric B. Dammer;Vivek Swarup;Divya Nandakumar

  • Evidence for brain glucose dysregulation in Alzheimer's disease

    Yang An;Vijay R. Varma;Sudhir Varma;Ramon Casanova

  • Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.

    S K Sieberts;T M Perumal;M M Carrasquillo;M Allen

  • Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.

    Srikant Rangaraju;Eric B. Dammer;Syed Ali Raza;Priyadharshini Rathakrishnan

  • U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.

    Bing Bai;Chadwick M. Hales;Ping Chung Chen;Yair Gozal

  • Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.

    Ying-Wooi Wan;Ying-Wooi Wan;Rami Al-Ouran;Rami Al-Ouran;Carl G. Mangleburg;Carl G. Mangleburg;Thanneer M. Perumal

  • The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis.

    Felix Willmund;Marta del Alamo;Sebastian Pechmann;Taotao Chen

  • Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer’s disease pathogenesis

    Aliza P. Wingo;Aliza P. Wingo;Yue Liu;Ekaterina S. Gerasimov;Jake Gockley

  • Integrated Proteomics Reveals Brain-Based Cerebrospinal Fluid Biomarkers in Asymptomatic and Symptomatic Alzheimer’s Disease

    Lenora Higginbotham;Lingyan Ping;Eric B. Dammer;Duc M. Duong

  • Polyubiquitin Linkage Profiles in Three Models of Proteolytic Stress Suggest the Etiology of Alzheimer Disease

    Eric B. Dammer;Chan Hyun Na;Ping Xu;Nicholas T. Seyfried

  • Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

    Erik C. B. Johnson;Eric B. Dammer;Duc M. Duong;Luming Yin

  • Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age

    Aliza P. Wingo;Eric B. Dammer;Michael S. Breen;Benjamin A. Logsdon

  • A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.

    Mfon E Umoh;Eric B Dammer;Jingting Dai;Duc M Duong

  • Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.

    Yi-Chen Hsieh;Caiwei Guo;Hari K. Yalamanchili;Measho Abreha

  • Coaggregation of RNA-Binding Proteins in a Model of TDP-43 Proteinopathy with Selective RGG Motif Methylation and a Role for RRM1 Ubiquitination

    Eric B. Dammer;Claudia Fallini;Yair M. Gozal;Duc M. Duong

  • P2-218: DEEP PROTEOMIC NETWORK ANALYSIS OF ALZHEIMER'S DISEASE BRAIN REVEALS ALTERATIONS IN RNA BINDING PROTEINS AND RNA SPLICING ASSOCIATED WITH DISEASE

    Erik C.B. Johnson;Eric B. Dammer;Duc Duong;Luming Yin

Frequent Co-Authors

Nicholas T. Seyfried
Nicholas T. Seyfried Emory University
Duc M. Duong
Duc M. Duong Emory University
James J. Lah
James J. Lah Emory University
Allan I. Levey
Allan I. Levey Emory University
Marla Gearing
Marla Gearing Emory University
Philip L. De Jager
Philip L. De Jager Columbia University
David A. Bennett
David A. Bennett Rush University Medical Center
Joshua M. Shulman
Joshua M. Shulman Baylor College of Medicine
Juan C. Troncoso
Juan C. Troncoso Johns Hopkins University School of Medicine
Vahram Haroutunian
Vahram Haroutunian Icahn School of Medicine at Mount Sinai

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