What is he best known for?
The fields of study he is best known for:
- Gene
- Amino acid
- G protein-coupled receptor
His main research concerns Cell biology, Heterotrimeric G protein, RGS Proteins, G protein-coupled receptor and GTP-Binding Protein alpha Subunits.
Mitosis is the focus of his Cell biology research.
His study in Heterotrimeric G protein focuses on G beta-gamma complex in particular.
His research on G protein-coupled receptor concerns the broader Biochemistry.
His GTP-Binding Protein alpha Subunits research includes themes of Gs alpha subunit, Gi alpha subunit and Thigmotropism.
His studies deal with areas such as G12/G13 alpha subunits and G alpha subunit as well as GTPase-activating protein.
His most cited work include:
- G-protein signaling: back to the future (375 citations)
- The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits. (327 citations)
- A Seven-Transmembrane RGS Protein That Modulates Plant Cell Proliferation (261 citations)
What are the main themes of his work throughout his whole career to date?
Francis S. Willard spends much of his time researching Cell biology, Heterotrimeric G protein, Biochemistry, G protein and G protein-coupled receptor.
His study in Cell biology focuses on RGS Proteins, Signal transduction, GTPase, GTPase-activating protein and Effector.
He works mostly in the field of RGS Proteins, limiting it down to concerns involving G alpha subunit and, occasionally, High-throughput screening.
His work on G beta-gamma complex and GTP-Binding Protein alpha Subunits as part of general Heterotrimeric G protein study is frequently connected to GTP', therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His G protein study combines topics from a wide range of disciplines, such as Guanine nucleotide exchange factor, Nucleotide and Second messenger system.
Francis S. Willard interconnects Cell surface receptor, Biophysics and Drug discovery in the investigation of issues within G protein-coupled receptor.
He most often published in these fields:
- Cell biology (51.46%)
- Heterotrimeric G protein (42.72%)
- Biochemistry (41.75%)
What were the highlights of his more recent work (between 2015-2021)?
- Receptor (23.30%)
- Agonist (9.71%)
- G protein-coupled receptor (28.16%)
In recent papers he was focusing on the following fields of study:
Francis S. Willard mainly investigates Receptor, Agonist, G protein-coupled receptor, Pharmacology and Drug discovery.
His Receptor research is multidisciplinary, incorporating perspectives in Biophysics and Signal transduction.
His G protein-coupled receptor research is multidisciplinary, relying on both Heterotrimeric G protein and G protein.
The Heterotrimeric G protein study combines topics in areas such as Gs alpha subunit, Second messenger system and Gq alpha subunit.
His Classical pharmacology study in the realm of Drug discovery interacts with subjects such as Phenotypic screening.
His Cell biology study frequently draws connections to adjacent fields such as Peptide sequence.
Between 2015 and 2021, his most popular works were:
- Activation of the GLP-1 receptor by a non-peptidic agonist (51 citations)
- Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles (35 citations)
- Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist (27 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Amino acid
- G protein-coupled receptor
His primary areas of investigation include Receptor, Type 2 Diabetes Mellitus, Drug discovery, Functional selectivity and Pharmacology.
Receptor is a subfield of Biochemistry that he studies.
His studies in Type 2 Diabetes Mellitus integrate themes in fields like Metabolic disease, Disease, Molecular Pharmacology and Bioinformatics.
His Drug discovery study integrates concerns from other disciplines, such as Glucagon, Insulin and G protein-coupled receptor.
His research investigates the link between Functional selectivity and topics such as Glucagon-like peptide 1 receptor that cross with problems in Extracellular, Biophysics, Transmembrane domain and Protein structure.
His research in Pharmacology intersects with topics in Diabetes mellitus and Mechanism of action.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
