Ajit Jadhav mostly deals with High-throughput screening, Biochemistry, Drug discovery, Structure–activity relationship and Small molecule. His biological study spans a wide range of topics, including Biological activity and Enzyme. Ajit Jadhav combines subjects such as Stereochemistry and Drug resistance with his study of Biochemistry.
His Drug discovery research integrates issues from Computational biology, Cell function and Combinatorial Chemistry Techniques. His Structure–activity relationship research includes themes of Mutant, Chaperone, Beta-Lactamase Inhibitors, Molecular model and Glucocerebrosidase. Ajit Jadhav combines subjects such as Molecular biology, Transcription, Gene, FOXM1 and Forkhead Transcription Factors with his study of Small molecule.
His primary scientific interests are in Biochemistry, Small molecule, High-throughput screening, Molecular biology and Pharmacology. Ajit Jadhav regularly links together related areas like Stereochemistry in his Biochemistry studies. His Small molecule study combines topics from a wide range of disciplines, such as Plasma protein binding, Cell biology, Methyltransferase and DNA damage.
His study connects Computational biology and High-throughput screening. His work in Molecular biology covers topics such as Cell culture which are related to areas like Cancer research. His Pharmacology study often links to related topics such as In vivo.
Biochemistry, Cancer research, Cancer, High-throughput screening and Cancer cell are his primary areas of study. His Biochemistry study frequently draws connections between related disciplines such as Pyrazole. His Cancer research study incorporates themes from Cell culture, Blockade, Estrogen receptor and Immunotherapy.
His High-throughput screening research is multidisciplinary, incorporating elements of Fumarase, Metabolic enzymes, Small molecule, Microscale thermophoresis and Malate dehydrogenase. He has included themes like Lactate dehydrogenase, Glycolysis, DNA repair, Cytotoxicity and DNA replication in his Cancer cell study. His Enzyme research incorporates themes from Cancer stem cell, Docking and Drug discovery.
Ajit Jadhav mainly investigates Biochemistry, Cancer research, Drug discovery, Human genome and Enzyme. His work on Small molecule, Protein structure and Cholesterol as part of his general Biochemistry study is frequently connected to Phosphatidylcholine—sterol O-acyltransferase, thereby bridging the divide between different branches of science. His work carried out in the field of Small molecule brings together such families of science as Carcinogenesis, Point mutation, High-throughput screening, Nucleosome and Histone methylation.
His study in Cancer research is interdisciplinary in nature, drawing from both Stimulator of interferon genes, Histone demethylase activity, Demethylase and Immunotherapy. His work deals with themes such as Paclitaxel and Aldehyde dehydrogenase, which intersect with Drug discovery. He has researched Enzyme in several fields, including Cancer stem cell and High-density lipoprotein.
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Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
Mingxun Wang;Jeremy J Carver;Vanessa V Phelan;Laura M Sanchez.
Nature Biotechnology (2016)
Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.
James Inglese;Douglas S. Auld;Ajit Jadhav;Ronald L. Johnson.
Proceedings of the National Academy of Sciences of the United States of America (2006)
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
Lesley A. Mathews Griner;Rajarshi Guha;Paul Shinn;Ryan M. Young.
Proceedings of the National Academy of Sciences of the United States of America (2014)
The NCGC Pharmaceutical Collection: A Comprehensive Resource of Clinically Approved Drugs Enabling Repurposing and Chemical Genomics
Ruili Huang;Noel Southall;Yuhong Wang;Adam Yasgar.
Science Translational Medicine (2011)
A high-throughput screen for aggregation-based inhibition in a large compound library.
Brian Y. Feng;Anton Simeonov;Ajit Jadhav;Kerim Babaoglu.
Journal of Medicinal Chemistry (2007)
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.
Fadi J. Najm;Mayur Madhavan;Anita Zaremba;Elizabeth Shick.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong.
PLOS Pathogens (2016)
Compound cytotoxicity profiling using quantitative high-throughput screening.
Menghang Xia;Ruili Huang;Kristine L. Witt;Noel Southall.
Environmental Health Perspectives (2007)
Fluorescence Spectroscopic Profiling of Compound Libraries
Anton Simeonov;Ajit Jadhav;Craig J. Thomas;Yuhong Wang.
Journal of Medicinal Chemistry (2008)
Unexplored therapeutic opportunities in the human genome.
Tudor I. Oprea;Cristian G. Bologa;Søren Brunak;Allen Campbell.
Nature Reviews Drug Discovery (2018)
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