Ajit Jadhav

Overview

Best Publications

• Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

  Mingxun Wang;Jeremy J Carver;Vanessa V Phelan;Laura M Sanchez

  4441
  Citations

• Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

  James Inglese;Douglas S. Auld;Ajit Jadhav;Ronald L. Johnson

  883
  Citations

• Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.

  Fadi J. Najm;Mayur Madhavan;Anita Zaremba;Elizabeth Shick

  465
  Citations

• The NCGC Pharmaceutical Collection: A Comprehensive Resource of Clinically Approved Drugs Enabling Repurposing and Chemical Genomics

  Ruili Huang;Noel Southall;Yuhong Wang;Adam Yasgar

  440
  Citations

• High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells

  Lesley A. Mathews Griner;Rajarshi Guha;Paul Shinn;Ryan M. Young

  427
  Citations

• Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

  Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong

  425
  Citations

• A high-throughput screen for aggregation-based inhibition in a large compound library.

  Brian Y. Feng;Anton Simeonov;Ajit Jadhav;Kerim Babaoglu

  408
  Citations

• Unexplored therapeutic opportunities in the human genome.

  Tudor I. Oprea;Cristian G. Bologa;Søren Brunak;Allen Campbell

  406
  Citations

• Pharos: Collating protein information to shed light on the druggable genome

  Dac-Trung Nguyen;Stephen L. Mathias;Cristian Bologa;Søren Brunak

  307
  Citations

• The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics.

  Ruili Huang;Ivan Grishagin;Yuhong Wang;Tongan Zhao

  299
  Citations

• Compound cytotoxicity profiling using quantitative high-throughput screening.

  Menghang Xia;Ruili Huang;Kristine L. Witt;Noel Southall

  291
  Citations

• A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

  Qin Liang;Thomas S Dexheimer;Ping Zhang;Andrew S Rosenthal

  282
  Citations

• Fluorescence Spectroscopic Profiling of Compound Libraries

  Anton Simeonov;Ajit Jadhav;Craig J. Thomas;Yuhong Wang

  281
  Citations

• Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors.

  Rafaela S. Ferreira;Anton Simeonov;Ajit Jadhav;Oliv Eidam

  266
  Citations

• Quantitative Analyses of Aggregation, Autofluorescence, and Reactivity Artifacts in a Screen for Inhibitors of a Thiol Protease

  Ajit Jadhav;Rafaela S. Ferreira;Carleen Klumpp;Bryan T. Mott

  263
  Citations

• Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.

  Feng Liu;Xin Chen;Abdellah Allali-Hassani;Amy M. Quinn

  244
  Citations

• Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors.

  Oliver N. F. King;Xuan Shirley Li;Masaaki Sakurai;Akane Kawamura

  241
  Citations

• Selective and Cell-Active Inhibitors of the USP1/ UAF1 Deubiquitinase Complex Reverse Cisplatin Resistance in Non-small Cell Lung Cancer Cells

  Junjun Chen;Thomas S. Dexheimer;Yongxing Ai;Qin Liang

  230
  Citations

• Characterization of chemical libraries for luciferase inhibitory activity.

  Douglas S. Auld;Noel T. Southall;Ajit Jadhav;Ronald L. Johnson

  226
  Citations

• Protein lysine methyltransferase g9a inhibitors: Design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines.

  Feng Liu;Xin Chen;Abdellah Allali-Hassani;Amy M. Quinn

  224
  Citations