D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 62 Citations 13,961 359 World Ranking 7006 National Ranking 3249

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

The scientist’s investigation covers issues in Pharmacology, Drug discovery, Drug development, Virology and Internal medicine. His work on Drug repositioning as part of general Pharmacology study is frequently connected to Chemokine receptor CCR5, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His work deals with themes such as High-throughput screening, Flux, Structure–activity relationship, Computational biology and High Throughput Assay, which intersect with Drug discovery.

His studies deal with areas such as Translational science, Equipment failure and Disease as well as Drug development. His Virology study combines topics in areas such as Druggability and Plasmodium falciparum. His Internal medicine research focuses on subjects like Endocrinology, which are linked to Intracellular.

His most cited work include:

  • Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries. (623 citations)
  • High-throughput screening assays for the identification of chemical probes (458 citations)
  • Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen (396 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Molecular biology, Cancer research, Cell biology and Pharmacology. His study involves Enzyme, Small molecule, High-throughput screening, Glucocerebrosidase and Enzyme assay, a branch of Biochemistry. His research investigates the connection between Molecular biology and topics such as Cell culture that intersect with issues in Cell.

His work in Cancer research tackles topics such as Induced pluripotent stem cell which are related to areas like Neural stem cell, Mutation, Disease, Pathophysiology and Lysosomal storage disease. His Drug and Drug repositioning study are his primary interests in Pharmacology. His Drug research focuses on Drug discovery and how it relates to Computational biology.

He most often published in these fields:

  • Biochemistry (13.17%)
  • Molecular biology (12.57%)
  • Cancer research (12.28%)

What were the highlights of his more recent work (between 2018-2021)?

  • Drug (10.78%)
  • Induced pluripotent stem cell (10.78%)
  • Cancer research (12.28%)

In recent papers he was focusing on the following fields of study:

His main research concerns Drug, Induced pluripotent stem cell, Cancer research, Drug repositioning and Drug development. His Drug research is multidisciplinary, incorporating elements of High-throughput screening, Drug resistance, Small molecule and Virology. The various areas that Wei Zheng examines in his Induced pluripotent stem cell study include Cell, Mutation, Molecular biology, Pathophysiology and Disease.

His Cancer research research incorporates themes from Cell culture, Ovarian cancer, In vivo and Exon. Pharmacology covers he research in Drug repositioning. In his study, which falls under the umbrella issue of Drug development, Computational biology is strongly linked to Drug discovery.

Between 2018 and 2021, his most popular works were:

  • Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium. (53 citations)
  • The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators (29 citations)
  • An OpenData portal to share COVID-19 drug repurposing data in real time. (27 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Wei Zheng mainly investigates Drug repositioning, Drug, Drug development, Disease and Pharmacology. Wei Zheng has included themes like Cytopathic effect, Virus and Approved drug in his Drug repositioning study. His Drug research includes themes of Protease and High-throughput screening.

His Drug development research integrates issues from Zika virus and Virology. The concepts of his Disease study are interwoven with issues in Phenotype, Efficacy, Drug discovery and Intensive care medicine. The study incorporates disciplines such as Computational biology and Neuroscience in addition to Drug discovery.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

James Inglese;Douglas S. Auld;Ajit Jadhav;Ronald L. Johnson.
Proceedings of the National Academy of Sciences of the United States of America (2006)

758 Citations

High-throughput screening assays for the identification of chemical probes

James Inglese;Ronald L Johnson;Anton Simeonov;Menghang Xia.
Nature Chemical Biology (2007)

634 Citations

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

Miao Xu;Emily M. Lee;Zhexing Wen;Yichen Cheng.
Nature Medicine (2016)

488 Citations

Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays.

Kelli Solly;Xiaobo Wang;Xiao Xu;Berta Strulovici.
Assay and Drug Development Technologies (2004)

445 Citations

Phenotypic screens as a renewed approach for drug discovery

Wei Zheng;Natasha Thorne;John C. McKew.
Drug Discovery Today (2013)

356 Citations

Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia

Alicia Cole;Zezhou Wang;Etienne Coyaud;Veronique Voisin.
Cancer Cell (2015)

264 Citations

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

Jennifer Kouznetsova;Wei Sun;Carles Martínez-Romero;Gregory Tawa.
Emerging microbes & infections (2014)

240 Citations

Identification and Characterization of Small Molecule Functional Antagonists of the CCR1 Chemokine Receptor

J. Hesselgesser;H. P. Ng;Meina Liang;Wei Zheng.
Journal of Biological Chemistry (1998)

228 Citations

Increased Expression of the Cardiac L-type Calcium Channel in Estrogen Receptor–deficient Mice

Barry D. Johnson;Wei Zheng;Kenneth S. Korach;Todd Scheuer.
The Journal of General Physiology (1997)

221 Citations

Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System.

Yi-Lan Weng;Yi-Lan Weng;Xu Wang;Ran An;Jessica Cassin.
Neuron (2018)

214 Citations

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