David J. Triggle

Research.com Recognitions

• 1985 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.

  G T Bolger;P Gengo;R Klockowski;E Luchowski

  433
  Citations

• Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG.

  Jiesheng Kang;Lin Wang;Xiao-Liang Chen;David J. Triggle

  386
  Citations

• Ca2+ channel ligands: Structure‐function relationships of the 1,4‐dihydropyridines

  David J. Triggle;David A. Langs;Ronald A. Janis

  378
  Citations

• 1,4-DIHYDROPYRIDINES AS CALCIUM CHANNEL LIGANDS AND PRIVILEGED STRUCTURES

  David J. Triggle

  348
  Citations

• Calcium channel antagonists: Clinical uses—Past, present and future

  David J. Triggle

  314
  Citations

• The actions of peppermint oil and menthol on calcium channel dependent processes in intestinal, neuronal and cardiac preparations

  M. Hawthorn;J. Ferrante;E. Luchowski;A. Rutledge

  297
  Citations

• 1,4‐Dihydropyridine Ca2+ channel antagonists and activators: A comparison of binding characteristics with pharmacology

  Ronald A. Janis;David J. Triggle

  266
  Citations

• CRYSTAL STRUCTURES OF CALCIUM CHANNEL ANTAGONISTS: 2,6-DIMETHYL-3,5-DICARBOMETHOXY-4-(2-NITRO-, 3-CYANO-, 4-(DIMETHYLAMINO)-, AND 2,3,4,5,6-PENTAFLUOROPHENYL)-1,4-DIHYDROPYRIDINE

  A. M. Triggle;E. Shefter;D. J. Triggle

  238
  Citations

• High affinity binding of a calcium channel antagonist to smooth and cardiac muscle

  G.T. Bolger;P.J. Gengo;E.M. Luchowski;H. Siegel

  235
  Citations

• The Pharmacology of Physostigmine

  David J. Triggle;John M. Mitchell;Ron Filler

  187
  Citations

• 1,4-Dihydropyridine activators and antagonists: structural and functional distinctions

  David J. Triggle;David Rampe

  172
  Citations

• 1,4-Dihydropyridine antagonist activities at the calcium channel: a quantitative structure-activity relationship approach.

  Robert A. Coburn;Mark Wierzba;Mark J. Suto;Alan J. Solo

  167
  Citations

• γ-Aminobutyric acid action in guinea-pig ileal myenteric plexus

  P.V. Kaplita;D.H. Waters;D.J. Triggle

  160
  Citations

• Chemical pharmacology of the synapse

  D.J. Triggle;C.R. Triggle

  158
  Citations

• Permanently charged chiral 1,4-dihydropyridines : Molecular probes of L-type calcium channels. Synthesis and pharmacological characterization of methyl (ω-trimethylalkylammonium) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate iodide, calcium channel antagonists

  Ravikumar Peri;Seetharamaiyer Padmanabhan;Aleta Rutledge;Satpal Singh

  149
  Citations

• Pharmacological, radioligand binding, and electrophysiological characteristics of FPL 64176, a novel nondihydropyridine Ca2+ channel activator, in cardiac and vascular preparations

  W Zheng;D Rampe;D J Triggle

  144
  Citations

• BAY K 8644, a 1,4-dihydropyridine Ca2+ channel activator: Dissociation of binding and functional effects in brain synaptosomes

  D. Rampe;R.A. Janis;D.J. Triggle

  138
  Citations

• Molecular properties of the slow inward calcium channel. Molecular weight determinations by radiation inactivation and covalent affinity labeling.

  J C Venter;C M Fraser;J S Schaber;C Y Jung

  135
  Citations

• The effects of Ca2+ antagonists on mechanical responses and Ca2+ movements in guinea pig ileal longitudinal smooth muscle

  Lois B. Rosenberger;M. K. Ticku;D. J. Triggle

  132
  Citations

• Characteristics of the binding of [3H] nitrendipine to rabbit ventricular membranes: modification by other Ca++ channel antagonists and by the Ca++ channel agonist bay K 8644

  R A Janis;J G Sarmiento;S C Maurer;G T Bolger

  128
  Citations