D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 63 Citations 13,775 436 World Ranking 5339 National Ranking 45

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Enzyme
  • Catalysis

Povl Krogsgaard-Larsen mainly focuses on Agonist, Stereochemistry, Receptor, Pharmacology and Biochemistry. His biological study spans a wide range of topics, including Biological activity, GABA receptor, GABAA receptor and Antagonist. His Stereochemistry research includes themes of AMPA receptor, Chemical synthesis and Stereoselectivity.

His research integrates issues of Biophysics and Glutamic acid in his study of Receptor. Povl Krogsgaard-Larsen combines subjects such as Mechanism of action, NMDA receptor, Tiagabine, GABA receptor antagonist and GABA Uptake Inhibitors with his study of Pharmacology. His work in the fields of Biochemistry, such as Nipecotic acid, intersects with other areas such as Calcium-sensing receptor.

His most cited work include:

  • Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations. (441 citations)
  • Ligands for glutamate receptors: design and therapeutic prospects. (418 citations)
  • New class of glutamate agonist structurally related to ibotenic acid (273 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Stereochemistry, Agonist, Receptor, AMPA receptor and Pharmacology. Excitatory postsynaptic potential is closely connected to Amino acid in his research, which is encompassed under the umbrella topic of Stereochemistry. Povl Krogsgaard-Larsen has researched Agonist in several fields, including Biological activity, Chiral column chromatography and GABAA receptor.

His Receptor research is within the category of Biochemistry. His AMPA receptor study integrates concerns from other disciplines, such as Ibotenic acid and Glutamic acid. Many of his studies on Pharmacology involve topics that are commonly interrelated, such as GABA receptor antagonist.

He most often published in these fields:

  • Stereochemistry (40.56%)
  • Agonist (26.84%)
  • Receptor (21.47%)

What were the highlights of his more recent work (between 2001-2018)?

  • Stereochemistry (40.56%)
  • Agonist (26.84%)
  • Receptor (21.47%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Stereochemistry, Agonist, Receptor, Pharmacology and GABAA receptor. His Stereochemistry study integrates concerns from other disciplines, such as Amino acid, Metabotropic glutamate receptor, Ibotenic acid, Chemical synthesis and Binding site. His Stereoselectivity research extends to Agonist, which is thematically connected.

His Receptor study is concerned with the field of Biochemistry as a whole. His Pharmacology research focuses on Tiagabine and how it connects with Transporter. His GABAA receptor study combines topics in areas such as Antagonist and Partial agonist.

Between 2001 and 2018, his most popular works were:

  • Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations. (441 citations)
  • Textbook of drug design and discovery (248 citations)
  • GABAA agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic (112 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Enzyme
  • Catalysis

His primary areas of study are Stereochemistry, Pharmacology, Receptor, Agonist and Biochemistry. Povl Krogsgaard-Larsen works on Stereochemistry which deals in particular with Bicyclic molecule. His studies in Pharmacology integrate themes in fields like GABA transporter, Transporter, Non-competitive inhibition, Tiagabine and Nipecotic acid.

His study in Agonist is interdisciplinary in nature, drawing from both Amino acid and Acetylcholine receptor. His GABAA receptor research includes themes of gamma-Aminobutyric acid and Antagonist. His research in Glutamate receptor intersects with topics in Biological activity and Ibotenic acid.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Neuronal nicotinic acetylcholine receptors: structural revelations, target identifications, and therapeutic inspirations.

Anders A Jensen;Bente Frølund;Tommy Liljefors;Povl Krogsgaard-Larsen.
Journal of Medicinal Chemistry (2005)

656 Citations

Ligands for glutamate receptors: design and therapeutic prospects.

Hans Bräuner-Osborne;Jan Egebjerg;Elsebet Ø. Nielsen;Ulf Madsen.
Journal of Medicinal Chemistry (2000)

635 Citations

New class of glutamate agonist structurally related to ibotenic acid

P. Krogsgaard-Larsen;T. Honoré;J. J. Hansen;D. R. Curtis.
Nature (1980)

400 Citations

Ketobemidone, methadone and pethidine are non-competitive N-methyl-D-aspartate (NMDA) antagonists in the rat cortex and spinal cord

Bjarke Ebert;Steen Andersen;Povl Krogsgaard-Larsen.
Neuroscience Letters (1995)

341 Citations

The Binding of [3H]AMPA, a Structural Analogue of Glutamic Acid, to Rat Brain Membranes

Tage Honoré;Jørn Lauridsen;Povl Krogsgaard-Larsen.
Journal of Neurochemistry (1982)

303 Citations

Textbook of drug design and discovery

Kristian Stromgaard;Povl Krogsgaard-Larsen;Ulf Madsen.
(2016)

273 Citations

GABA uptake inhibitors: relevance to antiepileptic drug research.

Povl Krogsgaard-Larsen;Erik Falch;Orla M. Larsson;Arne Schousboe.
Epilepsy Research (1987)

246 Citations

The agonist-binding domain of the calcium-sensing receptor is located at the amino-terminal domain.

Hans Bräuner-Osborne;Anders A. Jensen;Paul O. Sheppard;Patrick O'Hara.
Journal of Biological Chemistry (1999)

197 Citations

Effects of GABA analogues of restricted conformation on GABA transport in astrocytes and brain cortex slices and on GABA receptor binding.

A. Schousboe;P. Thorbek;L. Hertz;P. Krogsgaard-Larsen.
Journal of Neurochemistry (1979)

182 Citations

Novel Class of Potent 4-Arylalkyl Substituted 3-Isoxazolol GABAA Antagonists: Synthesis, Pharmacology, and Molecular Modeling

Bente Frølund;Anne T. Jørgensen;Lena Tagmose;Tine B. Stensbøl.
Journal of Medicinal Chemistry (2002)

178 Citations

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