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Neuroscience

D-Index
47
Citations
7352
World Ranking
6495
National Ranking
181

Overview

Mary Chebib is a researcher affiliated with the University of Sydney in Australia, with a body of work primarily spanning biochemistry, genetics, molecular biology, and neuroscience. Their research integrates molecular biology with neuropharmacology, focusing on mechanisms related to epilepsy, ion channel regulation, and neurodevelopmental disorders.

Their recent scholarly contributions include papers published between 2020 and 2022 in various scientific journals:

  • Gain-of-function and loss-of-function GABRB3 variants lead to distinct clinical phenotypes in patients with developmental and epileptic encephalopathies, 2022, Nature Communications
  • Gain-of-function variants in GABRD reveal a novel pathway for neurodevelopmental disorders and epilepsy, 2021, Brain
  • Cannabigerolic acid, a major biosynthetic precursor molecule in cannabis, exhibits divergent effects on seizures in mouse models of epilepsy, 2021, British Journal of Pharmacology
  • Gain-of-function GABRB3 variants identified in vigabatrin-hypersensitive epileptic encephalopathies, 2020, Brain Communications
  • The Z-Drugs Zolpidem, Zaleplon, and Eszopiclone Have Varying Actions on Human GABAA Receptors Containing γ1, γ2, and γ3 Subunits, 2020, Frontiers in Neuroscience

Mary Chebib has collaborated frequently with several other researchers, including Vivian W. Y. Liao, Philip K. Ahring, Rikke S. Møller, Nathan L. Absalom, and Katrine M. Johannesen. These collaborations suggest active engagement across teams focused on neuropharmacology and genetics related to neurological disorders.

Their publications are often featured in journals specializing in neuroscience and pharmacology. The most frequent venues for their work include:

  • Brain
  • British Journal of Pharmacology
  • Annals of Neurology
  • Neuropharmacology
  • Nature Communications

Mary Chebib's research fields and subfields comprise:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Genetics
  • Psychiatry and Mental health
  • Pharmacology

Their main topics of study cover:

  • Neuroscience and Neuropharmacology Research
  • Epilepsy research and treatment
  • Ion channel regulation and function
  • Nicotinic Acetylcholine Receptors Study
  • Genetics and Neurodevelopmental Disorders
  • RNA and protein synthesis mechanisms
  • Mitochondrial Function and Pathology

Best Publications

  • The 'ABC' of GABA receptors: a brief review.

    Mary Chebib;Graham A R Johnston

  • GABA-Activated ligand gated ion channels: medicinal chemistry and molecular biology.

    Mary Chebib;Graham A. R. Johnston

  • Flavonoid modulation of GABAA receptors

    Jane R. Hanrahan;Mary Chebib;Graham A. R. Johnston

  • The Direct Actions of Cannabidiol and 2-arachidonoyl Glycerol at GABA A Receptors

    T. Bakas;P.S. van Nieuwenhuijzen;S.O. Devenish;I.S. McGregor

  • The dietary flavonoids apigenin and (−)-epigallocatechin gallate enhance the positive modulation by diazepam of the activation by GABA of recombinant GABAA receptors

    Erica L. Campbell;Mary Chebib;Graham A.R. Johnston

  • Alpha9 nicotinic acetylcholine receptors and the treatment of pain.

    J. Michael McIntosh;Nathan Absalom;Mary Chebib;Ana Belén Elgoyhen

  • GABAA Receptors and the Diversity in their Structure and Pharmacology.

    Han Chow Chua;Mary Chebib

  • Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions.

    Lyndsey L. Anderson;Nathan L. Absalom;Sarah V. Abelev;Ivan K. Low

  • The Flavonoid Glycosides, Myricitrin, Gossypin and Naringin Exert Anxiolytic Action in Mice

    Sebastian P. Fernandez;Michael Nguyen;Tin Thing Yow;Cindy Chu

  • Modulation of ionotropic GABA receptors by natural products of plant origin.

    Graham A R Johnston;Jane R Hanrahan;Mary Chebib;Rujee K Duke

  • Contrasting Modes of Action of Methylglutamate Derivatives on the Excitatory Amino Acid Transporters, EAAT1 and EAAT2

    Robert J. Vandenberg;Ann D. Mitrovic;Mary Chebib;Vladimir J. Balcar

  • The β‐amyloid protein of Alzheimer’s disease binds to membrane lipids but does not bind to the α7 nicotinic acetylcholine receptor

    David Henry Small;Danuta Maria Maksel;M Kerr;Judy Hoi Pui Ng

  • GABAC Receptors as Drug Targets

    Graham A R Johnston;Mary Chebib;Jane R Hanrahan;Kenneth N Mewett

  • α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB).

    Nathan Absalom;Laura F. Eghorn;Inge S. Villumsen;Nasiara Karim

  • Gain-of-function and loss-of-function GABRB3 variants lead to distinct clinical phenotypes in patients with developmental and epileptic encephalopathies

    Unknown

  • Novel, Potent, and Selective GABAC Antagonists Inhibit Myopia Development and Facilitate Learning and Memory

    Mary Chebib;Tina Hinton;Katrina L. Schmid;Darren Brinkworth

  • Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism.

    Han Chow Chua;Emilie T. H. Christensen;Emilie T. H. Christensen;Kirsten Hoestgaard-Jensen;Leonny Y. Hartiadi

  • Bilobalide, a sesquiterpene trilactone from Ginkgo biloba, is an antagonist at recombinant α1β2γ2L GABAA receptors

    Shelley H Huang;Rujee K Duke;Mary Chebib;Keiko Sasaki

  • Semisynthetic preparation of amentoflavone: A negative modulator at GABAA receptors

    Jane R. Hanrahan;Mary Chebib;Neil L.M. Davucheron;Belinda J. Hall

  • GABAC RECEPTOR ION CHANNELS

    M Chebib

  • Ginkgolides, diterpene trilactones of Ginkgo biloba, as antagonists at recombinant α1β2γ2L GABAA receptors

    Shelley H Huang;Rujee K Duke;Mary Chebib;Keiko Sasaki

  • GABAC receptor antagonists differentiate between human ρ1 and ρ2 receptors expressed in Xenopus oocytes

    Mary Chebib;Kenneth N. Mewett;Graham A.R. Johnston

Frequent Co-Authors

J. Michael McIntosh
J. Michael McIntosh University of Utah
Dusan Losic
Dusan Losic University of Adelaide
Rikke S. Møller
Rikke S. Møller University of Southern Denmark
Eric J. Gowans
Eric J. Gowans University of Adelaide
Jeffrey D. Rothstein
Jeffrey D. Rothstein Johns Hopkins University
Ana Belén Elgoyhen
Ana Belén Elgoyhen University of Buenos Aires
Manju A. Kurian
Manju A. Kurian University College London
Jesper V. Olsen
Jesper V. Olsen University of Copenhagen
Evan E. Eichler
Evan E. Eichler University of Washington
Holger Lerche
Holger Lerche University of Tübingen

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