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Neuroscience

D-Index
41
Citations
10095
World Ranking
7763
National Ranking
3332

Overview

Alicia A. Walf is affiliated with Rensselaer Polytechnic Institute in the United States. Their research spans several fields within medicine and the neurosciences, with a particular focus on the biochemical and genetic aspects of these disciplines.

Their work primarily centers on the study of hormonal and reproductive systems, with emphasis on estrogen-related effects and the neuroendocrine regulation of stress responses. The research also covers menopausal health impacts, Alzheimer's disease, dementia, cognitive impairment, and olfactory and sensory function studies. These topics reflect the broad application of their research within both clinical and behavioral neuroscience contexts.

Walf's published papers include studies on hormone effects and neurosteroids relevant to cognitive performance and androgen knowledge. Recent publications are:

  • "Progesterone's Effects on Cognitive Performance of Male Mice Are Independent of Progestin Receptors but Relate to Increases in GABAA Activity in the Hippocampus and Cortex" (2021, Frontiers in Endocrinology)
  • "Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role" (2020, Current Sexual Health Reports)

Frequent co-authors collaborating with Walf include:

  • Cheryl A. Frye
  • Vincent F. Lembo
  • Dan DaCosta
  • Vincenzo F. Lembo
  • Larry D. Reid

The primary venues for their scientific publications are

  • Frontiers in Endocrinology
  • Current Sexual Health Reports

Walf works across multiple interconnected fields of study:

  • Medicine
  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology

Within these fields, their research is detailed further into subfield specializations:

  • Genetics
  • Endocrinology, Diabetes and Metabolism
  • Behavioral Neuroscience
  • Physiology
  • Sensory Systems

Their main research topics clearly engage with:

  • Estrogen and related hormone effects
  • Stress Responses and Cortisol
  • Menopause: Health Impacts and Treatments
  • Hormonal and reproductive studies
  • Alzheimer's disease research and treatments
  • Olfactory and Sensory Function Studies
  • Dementia and Cognitive Impairment Research

Best Publications

  • The use of the elevated plus maze as an assay of anxiety-related behavior in rodents

    Alicia A Walf;Cheryl A Frye

  • A review and update of mechanisms of estrogen in the hippocampus and amygdala for anxiety and depression behavior.

    Alicia A Walf;Cheryl A Frye

  • Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous rats.

    Cheryl A. Frye;Alicia A. Walf

  • Estrogens and progestins enhance spatial learning of intact and ovariectomized rats in the object placement task.

    Cheryl A. Frye;Caryn K. Duffy;Alicia A. Walf

  • Ovarian steroids enhance object recognition in naturally cycling and ovariectomized, hormone-primed rats.

    Alicia A. Walf;Madeline E. Rhodes;Cheryl A. Frye

  • ERbeta-selective estrogen receptor modulators produce antianxiety behavior when administered systemically to ovariectomized rats.

    Alicia A Walf;Cheryl A Frye

  • Estrogen and/or progesterone administered systemically or to the amygdala can have anxiety-, fear-, and pain-reducing effects in ovariectomized rats.

    Cheryl A. Frye;Alicia A. Walf

  • Antidepressant effects of ERβ-selective estrogen receptor modulators in the forced swim test

    Alicia A Walf;Madeline E Rhodes;Cheryl A Frye

  • Administration of estrogen receptor beta-specific selective estrogen receptor modulators to the hippocampus decrease anxiety and depressive behavior of ovariectomized rats.

    Alicia A Walf;Cheryl A Frye

  • Proestrous compared to diestrous wildtype, but not estrogen receptor beta knockout, mice have better performance in the spontaneous alternation and object recognition tasks and reduced anxiety-like behavior in the elevated plus and mirror maze

    Alicia A. Walf;Carolyn Koonce;Kevin Manley;Cheryl A. Frye

  • Antianxiety and antidepressive behavior produced by physiological estradiol regimen may be modulated by hypothalamic-pituitary-adrenal axis activity

    Alicia A Walf;Cheryl A Frye

  • Neurosteroidogenesis today: Novel targets for neuroactive steroid synthesis and action and their relevance for translational research.

    P. Porcu;A. M. Barron;C. A. Frye;C. A. Frye;A. A. Walf;A. A. Walf;A. A. Walf

  • Estradiol or diarylpropionitrile administration to wild type, but not estrogen receptor beta knockout, mice enhances performance in the object recognition and object placement tasks.

    Alicia A. Walf;Carolyn J. Koonce;Cheryl A. Frye

  • Chronic estradiol replacement to aged female rats reduces anxiety-like and depression-like behavior and enhances cognitive performance.

    Alicia A. Walf;Jason J. Paris;Cheryl A. Frye

  • Estrogen action: a historic perspective on the implications of considering alternative approaches

    Elwood V. Jensen;Herbert I. Jacobson;Alicia A. Walf;Cheryl A. Frye

  • Progesterone enhances motor, anxiolytic, analgesic, and antidepressive behavior of wild-type mice, but not those deficient in type 1 5α-reductase

    Cheryl A Frye;Alicia A Walf;Madeline E Rhodes;Jacob P Harney

  • Estradiol or Diarylpropionitrile Decrease Anxiety-Like Behavior of Wildtype, but Not Estrogen Receptor Beta Knockout, Mice

    Alicia A Walf;Carolyn J Koonce;Cheryl A Frye

  • Androgens with activity at estrogen receptor beta have anxiolytic and cognitive-enhancing effects in male rats and mice

    Cheryl A. Frye;Carolyn J. Koonce;Kassandra L. Edinger;Danielle M. Osborne

  • Estradiol reduces anxiety- and depression-like behavior of aged female mice

    Alicia A. Walf;Cheryl A. Frye

  • Depression-like behavior of aged male and female mice is ameliorated with administration of testosterone or its metabolites

    Cheryl A. Frye;Alicia A. Walf

  • Progesterone Reduces Pentylenetetrazol-Induced Ictal Activity of Wild-Type Mice But Not Those Deficient in Type I 5α-Reductase

    Cheryl A. Frye;Madeline E. Rhodes;Alicia Walf;Jacob Harney

Frequent Co-Authors

Cheryl A. Frye
Cheryl A. Frye University at Albany, State University of New York
Gérard Tramu
Gérard Tramu University of Bordeaux
Dick F. Swaab
Dick F. Swaab Royal Netherlands Academy of Arts and Sciences
Elly M. Hol
Elly M. Hol Utrecht University
Inge Huitinga
Inge Huitinga Netherlands Institute for Neuroscience
Marco Bortolato
Marco Bortolato University of Florida
Giancarlo Panzica
Giancarlo Panzica University of Turin
Luis M. Garcia-Segura
Luis M. Garcia-Segura Spanish National Research Council
David P. Jarmolowicz
David P. Jarmolowicz University of Kansas
James W. Simpkins
James W. Simpkins West Virginia University

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