2019 - Member of Academia Europaea
Neuroscience, Astrocyte, Microglia, Astrogliosis and Pathology are her primary areas of study. The concepts of her Neuroscience study are interwoven with issues in Gliogenesis, Angiogenesis, Transcriptome and Apolipoprotein E, Disease. Her Astrocyte study combines topics from a wide range of disciplines, such as Intermediate filament, Alexander disease and Cell biology.
She combines subjects such as Phagocytosis, Gene expression, Phenotype, Neural development and Cell type with her study of Microglia. Her work is dedicated to discovering how Astrogliosis, Subgranular zone are connected with Nestin, Glial fibrillary acidic protein and Gliosis and other disciplines. She interconnects Biomarker, Psychopharmacology and Immune system in the investigation of issues within Pathology.
Her primary scientific interests are in Neuroscience, Cell biology, Microglia, Pathology and Glial fibrillary acidic protein. Her Neuroscience research is multidisciplinary, relying on both Stroke, Disease and Neural stem cell. Her work on Subventricular zone and Proteasome as part of general Cell biology study is frequently linked to Population, therefore connecting diverse disciplines of science.
As a part of the same scientific family, Elly M. Hol mostly works in the field of Microglia, focusing on Gene expression and, on occasion, Downregulation and upregulation. Her work investigates the relationship between Pathology and topics such as Astrogliosis that intersect with problems in Subgranular zone and Dementia. Her Glial fibrillary acidic protein research is multidisciplinary, incorporating elements of Intermediate filament, Molecular biology, Nestin, Vimentin and Gene isoform.
Her primary areas of study are Microglia, Neuroscience, Pathology, Cell biology and Immunology. Her Microglia research is multidisciplinary, incorporating perspectives in Phenotype, Transcriptome, Neuroinflammation, Neurology and Subarachnoid hemorrhage. Astrocyte and Astrogliosis are among the areas of Neuroscience where the researcher is concentrating her efforts.
Elly M. Hol studies Pathology, focusing on Glial fibrillary acidic protein in particular. Elly M. Hol conducted interdisciplinary study in her works that combined Cell biology and Population. As a part of the same scientific study, Elly M. Hol usually deals with the Immunology, concentrating on Apolipoprotein E and frequently concerns with GPNMB, CD11c, Integrin alpha M, Senile plaques and Inflammation.
Her primary areas of investigation include Microglia, Neuroscience, Apolipoprotein E, Pathology and Immunology. The concepts of her Microglia study are interwoven with issues in Gliogenesis, Neural development, Angiogenesis and Cell biology. Her Neuroscience study typically links adjacent topics like Neuropathology.
Her work focuses on many connections between Apolipoprotein E and other disciplines, such as TREM2, that overlap with her field of interest in Cellular differentiation, Dementia and Neuroinflammation. Elly M. Hol has included themes like Biomarker, Temporal cortex and Schizophrenia in her Pathology study. Her Astrocyte research incorporates themes from Oxidative stress, Glutamate receptor, Alexander disease, Stroke and Disease.
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GFAP in Health and Disease
J. Middeldorp;E.M. Hol.
Progress in Neurobiology (2011)
Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.
Rixt F. Riemersma-van der Lek;Dick F. Swaab;Jos Twisk;Elly M. Hol.
Frameshift Mutants of β Amyloid Precursor Protein and Ubiquitin-B in Alzheimer's and Down Patients
Fred W. van Leeuwen;Dominique P. V. de Kleijn;Helma H. van den Hurk;Andrea Neubauer.
Astrocytes: a central element in neurological diseases
Milos Pekny;Milos Pekny;Milos Pekny;Marcela Pekna;Marcela Pekna;Marcela Pekna;Albee Messing;Christian Steinhäuser.
Acta Neuropathologica (2016)
Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system.
Elly M Hol;Elly M Hol;Elly M Hol;Milos Pekny;Milos Pekny;Milos Pekny.
Current Opinion in Cell Biology (2015)
Reactive astrocyte nomenclature, definitions, and future directions
Carole Escartin;Elena Galea;András Lakatos;James P. O’Callaghan.
Nature Neuroscience (2021)
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
Inge R Holtman;Divya D Raj;Jeremy A Miller;Wandert Schaafsma.
Acta neuropathologica communications (2015)
The Indispensable Roles of Microglia and Astrocytes during Brain Development
Kitty Reemst;Stephen C. Noctor;Paul J. Lucassen;Elly M. Hol;Elly M. Hol;Elly M. Hol.
Frontiers in Human Neuroscience (2016)
Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction
Marie Orre;Willem Kamphuis;Lana M Osborn;Lana M Osborn;Anne H P Jansen.
Neurobiology of Aging (2014)
Microglia innately develop within cerebral organoids.
Paul R. Ormel;Renata Vieira de Sá;Emma J. van Bodegraven;Henk Karst.
Nature Communications (2018)
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