Willem Kamphuis

Best Publications

• Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis

  Inge R Holtman;Divya D Raj;Jeremy A Miller;Wandert Schaafsma

  680
  Citations

• Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction

  Marie Orre;Willem Kamphuis;Lana M Osborn;Lana M Osborn;Anne H P Jansen

  446
  Citations

• GFAP Isoforms in Adult Mouse Brain with a Focus on Neurogenic Astrocytes and Reactive Astrogliosis in Mouse Models of Alzheimer Disease

  Willem Kamphuis;Carlyn Mamber;Martina Moeton;Lieneke Kooijman

  361
  Citations

• Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances

  S.S. Wang;W. Kamphuis;I. Huitinga;J.N. Zhou

  341
  Citations

• Astrogliosis: An integral player in the pathogenesis of Alzheimer's disease.

  Lana M. Osborn;Willem Kamphuis;Wytse J. Wadman;Elly M. Hol

  325
  Citations

• Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice

  Marie Orre;Willem Kamphuis;Lana M. Osborn;Lana M. Osborn;Jeroen Melief

  283
  Citations

• Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease

  Willem Kamphuis;Jinte Middeldorp;Jinte Middeldorp;Lieneke Kooijman;Jacqueline A. Sluijs

  277
  Citations

• Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease

  Zhuoran Yin;Divya Raj;Nasrin Saiepour;Debby Van Dam

  246
  Citations

• Enteric GFAP expression and phosphorylation in Parkinson's disease.

  Thomas Clairembault;Thomas Clairembault;Willem Kamphuis;Laurène Leclair-Visonneau;Laurène Leclair-Visonneau;Malvyne Rolli-Derkinderen;Malvyne Rolli-Derkinderen

  224
  Citations

• Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease.

  Willem Kamphuis;Lieneke Kooijman;Sjoerd Schetters;Marie Orre

  219
  Citations

• Reactive glia show increased immunoproteasome activity in Alzheimer's disease.

  Marie Orre;Willem Kamphuis;Stephanie Dooves;Lieneke Kooijman

  208
  Citations

• GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease

  Willem Kamphuis;Lieneke Kooijman;Lieneke Kooijman;Marie Orre;Omja Oscar Stassen

  176
  Citations

• Differential cell proliferation in the cortex of the APPswePS1dE9 Alzheimer's disease mouse model.

  Willem Kamphuis;Marie Orre;Lieneke Kooijman;Maurice Dahmen

  175
  Citations

• Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer’s disease

  Marlene J Végh;Céline M Heldring;Willem Kamphuis;Sara Hijazi

  156
  Citations

• Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors.

  Alan R Harvey;W Kamphuis;R Eggers;N A Symons

  153
  Citations

• Deep brain stimulation and the role of astrocytes

  V Vedam-Mai;E Y van Battum;W Kamphuis;M G P Feenstra

  153
  Citations

• Circadian expression of clock genes and clock-controlled genes in the rat retina.

  Willem Kamphuis;Cathy Cailotto;Frederike Dijk;Arthur Bergen

  147
  Citations

• Kindling induced changes in parvalbumin immunoreactivity in rat hippocampus and its relation to long-term decrease in GABA-immunoreactivity

  Willem Kamphuis;Evelien Huisman;Wytse J. Wadman;Claus W. Heizmann

  137
  Citations

• Changes in local evoked potentials in the rat hippocampus (CA1) during kindling epileptogenesis.

  Willem Kamphuis;Fernando H. Lopes da Silva;Wytse J. Wadman

  122
  Citations

• Aberrant stress hormone receptor balance in the human prefrontal cortex and hypothalamic paraventricular nucleus of depressed patients

  Xin-Rui Qi;Willem Kamphuis;Shanshan Wang;Qian Wang

  122
  Citations