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Javier Vitorica

Javier Vitorica

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
16766
World Ranking
15384
National Ranking
332

Overview

Javier Vitorica is affiliated with the University of Seville in Spain and specializes in neuroscience and medicine. Their research primarily focuses on neuroinflammation, neurodegeneration mechanisms, and Alzheimer's disease research and treatments. The scientist's work spans several subfields including neurology, physiology, immunology, cellular and molecular neuroscience, and molecular biology.

Research topics covered by Javier Vitorica include:

  • Neuroinflammation and neurodegeneration mechanisms
  • Alzheimer's disease research and treatments
  • Neurological disease mechanisms and treatments
  • Inflammation biomarkers and pathways
  • Galectins and cancer biology
  • Immune cells in cancer
  • Apelin-related biomedical research

Frequent coauthors in their research collaborations are:

  • Antonia Gutiérrez
  • Elisabeth Sánchez-Mejías
  • Marisa Vizuete
  • Sebastián Jiménez
  • Victoria Navarro

Javier Vitorica has published extensively in several prominent venues. The most frequent publication venues include:

  • Alzheimer s & Dementia
  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • IBRO Neuroscience Reports
  • Glia

Some recent papers authored or co-authored by Javier Vitorica are:

  • "Reactive astrocyte nomenclature, definitions, and future directions," 2021, Nature Neuroscience
  • "Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1," 2021, Nature Aging
  • "Transgenic Mouse Models of Alzheimer's Disease: An Integrative Analysis," 2022, International Journal of Molecular Sciences
  • "Amyloid-β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease," 2020, Glia
  • "Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease," 2022, Acta Neuropathologica Communications

Best Publications

  • Neuroinflammation in Alzheimer's disease

    Michael T Heneka;Monica J Carson;Joseph El Khoury;Gary E Landreth

  • Reactive astrocyte nomenclature, definitions, and future directions

    Carole Escartin;Elena Galea;András Lakatos;James P. O’Callaghan

  • Inflammatory Response in the Hippocampus of PS1M146L/APP751SL Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to Classic

    Sebastian Jimenez;David Baglietto-Vargas;Cristina Caballero;Ines Moreno-Gonzalez

  • Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease

    Antonio Boza-Serrano;Rocío Ruiz;Raquel Sánchez-Varo;Juan García-Revilla

  • Differential expression of the short and long forms of the γ2 subunit of the GABAA/benzodiazepine receptors

    Celia P. Miralles;Antonia Gutie´rrez;Zafar U. Khan;Javier Vitorica

  • Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1 × APP transgenic model of Alzheimer's disease

    Blanca Ramos;David Baglietto-Vargas;Juan Carlos del Rio;Ines Moreno-Gonzalez

  • Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus

    Raquel Sanchez-Varo;Laura Trujillo-Estrada;Elisabeth Sanchez-Mejias;Manuel Torres;Manuel Torres

  • Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model *

    Sebastian Jimenez;Manuel Torres;Manuel Torres;Marisa Vizuete;Marisa Vizuete;Raquel Sanchez-Varo

  • Microglia in Alzheimer's Disease: Activated, Dysfunctional or Degenerative.

    Victoria Navarro;Victoria Navarro;Elisabeth Sanchez-Mejias;Sebastian Jimenez;Sebastian Jimenez;Clara Muñoz-Castro;Clara Muñoz-Castro

  • Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease.

    Angela Gomez-Arboledas;Jose C. Davila;Elisabeth Sanchez-Mejias;Victoria Navarro

  • Cellular environment facilitates protein accumulation in aged rat hippocampus

    M. Paz Gavilán;José Vela;Angélica Castaño;Blanca Ramos

  • Localization of the GABAA receptor in the rat brain with a monoclonal antibody to the 57,000 Mr peptide of the GABAA receptor/benzodiazepine receptor/Cl- channel complex.

    AL de Blas;J Vitorica;P Friedrich

  • Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration

    Elisabeth Sanchez-Mejias;Victoria Navarro;Victoria Navarro;Sebastian Jimenez;Sebastian Jimenez;Maria Sanchez-Mico;Maria Sanchez-Mico

  • Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus

    Manuel Torres;Manuel Torres;Sebastian Jimenez;Sebastian Jimenez;Raquel Sanchez-Varo;Victoria Navarro;Victoria Navarro

  • Comparative autoradiographic distribution of central ω (benzodiazepine) modulatory site subtypes with high, intermediate and low affinity for zolpidem and alpidem

    J. Benavides;B. Peny;D. Ruano;J. Vitorica

  • Monoclonal antibodies and conventional antisera to the GABAA receptor/benzodiazepine receptor/Cl- channel complex

    J. Vitorica;Dongeun Park;G. Chin;A. L. De Blas

  • Rat hippocampal GABAergic molecular markers are differentially affected by ageing.

    José Vela;Antonia Gutierrez;Javier Vitorica;Diego Ruano

  • Calretinin Interneurons are Early Targets of Extracellular Amyloid-β Pathology in PS1/AβPP Alzheimer Mice Hippocampus

    David Baglietto-Vargas;Ines Moreno-Gonzalez;Raquel Sanchez-Varo;Sebastian Jimenez;Sebastian Jimenez

  • Involvement of mitochondria in the age-dependent decrease in calcium uptake of rat brain synaptosomes.

    Javier Vitorica;Jorgina Satru´stegui

  • Neuroinfl ammation in Alzheimer's disease

    Michael T Heneka;Monica J Carson;Joseph El Khoury;Gary E Landreth

Frequent Co-Authors

Antonia Gutierrez
Antonia Gutierrez University of Malaga
Jorgina Satrústegui
Jorgina Satrústegui Spanish National Research Council
Angel L. De Blas
Angel L. De Blas University of Connecticut
Tamara García-Barrera
Tamara García-Barrera University of Huelva
José Luis Gómez-Ariza
José Luis Gómez-Ariza University of Huelva
Alexei Verkhratsky
Alexei Verkhratsky University of Manchester
Guy C. Brown
Guy C. Brown University of Cambridge
Elena Galea
Elena Galea Autonomous University of Barcelona
José López-Barneo
José López-Barneo Spanish National Research Council
Richard M. Ransohoff
Richard M. Ransohoff Harvard University

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